ID A0A135LRS6_PENPA Unreviewed; 1224 AA.
AC A0A135LRS6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=PX-associated, sorting nexin 13 {ECO:0000313|EMBL:KXG51641.1};
GN ORFNames=PGRI_090340 {ECO:0000313|EMBL:KXG51641.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG51641.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG51641.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG51641.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- SIMILARITY: Belongs to the sorting nexin family.
CC {ECO:0000256|ARBA:ARBA00010883}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG51641.1}.
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DR EMBL; LHQR01000029; KXG51641.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LRS6; -.
DR STRING; 5078.A0A135LRS6; -.
DR OMA; AMYVVEV; -.
DR OrthoDB; 5392990at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043226; C:organelle; IEA:UniProt.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR CDD; cd06876; PX_MDM1p; 1.
DR Gene3D; 3.30.1520.10; Phox-like domain; 1.
DR Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR InterPro; IPR003114; Phox_assoc.
DR InterPro; IPR001683; PX_dom.
DR InterPro; IPR036871; PX_dom_sf.
DR InterPro; IPR016137; RGS.
DR InterPro; IPR036305; RGS_sf.
DR InterPro; IPR044926; RGS_subdomain_2.
DR InterPro; IPR013937; Sorting_nexin_C.
DR PANTHER; PTHR22775; SORTING NEXIN; 1.
DR PANTHER; PTHR22775:SF3; SORTING NEXIN-13; 1.
DR Pfam; PF08628; Nexin_C; 1.
DR Pfam; PF00787; PX; 1.
DR Pfam; PF02194; PXA; 1.
DR Pfam; PF00615; RGS; 1.
DR SMART; SM00312; PX; 1.
DR SMART; SM00313; PXA; 1.
DR SMART; SM00315; RGS; 1.
DR SUPFAM; SSF64268; PX domain; 1.
DR SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR PROSITE; PS50195; PX; 1.
DR PROSITE; PS51207; PXA; 1.
DR PROSITE; PS50132; RGS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070168};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 7..26
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 32..55
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 99..288
FT /note="PXA"
FT /evidence="ECO:0000259|PROSITE:PS51207"
FT DOMAIN 414..551
FT /note="RGS"
FT /evidence="ECO:0000259|PROSITE:PS50132"
FT DOMAIN 862..980
FT /note="PX"
FT /evidence="ECO:0000259|PROSITE:PS50195"
FT REGION 300..320
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 565..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 688..725
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 763..782
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 614..639
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 640..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1224 AA; 137497 MW; 67B87D9C306557AA CRC64;
MALSRRDLVL AGVGVFIAWG LVVRWLPILR YLGYAVTLGA VLSSVGLLGL VTLTIRHQNG
KINTKNVSVA FIKPNQWRKE VLNVRRGTRY RPRPLYPQSF VVSEGLDELL SFIIRDFVSS
WYHSISPNPI FANEVDRTIR VALENLRDRL VAEDMISLIV SRIFPIVTSH LKEFDIAERS
VRGRNLSRNV TESGELNLAI ANKYREGRLH PAVATAASDQ KAVQQEYLRK LAVGLLPQLF
PENVLNSRIV SVLIREIISC AVLTPIVTSL SDPDTWNQLM EAYGRTALQD RKTVRKLRAA
LDQHASPAPK SKRGQPFPRL SATDSERAFE RFVRAIRKCN NLSDARRFRA LVSSQLKQES
VVEGQDQVYL KRLETGKRVL DQKVAKLAKT GEDSHVPPAL DLRPEIPYRM HESSLVDVMH
SASGLSYFME FMDRQKLMSL VQFWIVVDGL RNPLEDDFGD EEAPTSLAWK PADRNDLALI
SESYLSKPEL KVSEESRRAV KTFLSAGKRA TPEQYRKARM VVLTTQSAIL EHLQETYYPK
FKESDLYWKY LASDEASAAQ ATVRQSSPIS VTFETPERRP LPPLLSRTTS QPGLRPSKDL
RRAAVSSSSD LRGTGKLFDD DDSPRRSIDS ERSTNLFDDD YDTDNLATST HSLGKDSHNG
ENDASQSQSQ VLETMEAALN DIITNEPKNG RIEDLKGDAA GLFGPERPVL SSRSSSEIPQ
VDNRNERTKK SIASLGLVDH ASRLGVFDDD LFPDQQKFIE DEYEEPDGED EKDPADEVHE
AAPGDLGLTE AIEALSVDID KLAAQDSVVQ ALTRKAELTN NTAELRILRK SKASIQREMH
RKEMQRQQYI LQESDNSLFG RSTVSIKSIV VGKDEDDGRE FAMYVIEVRR NAGEQMPAAS
WVVARRYSEF HDLHQKLRQR YPSVRHLEFP RRRVVMKLQK EFLDKRRLAL EAYLQKLLLL
PEVCRSRDLR AFLSQRAILP RKDNARDNEG ETKDLVTRIY NSVADGMDDF LGNFGVLDQL
STAGQNLISA ATQQANTTTV PDSSLVAEDA VTAAEAEAEL NAFEDRELEP FIKPICDLFL
EAFELNRGNN WLRGRAVVVV LHQLLGGTIE RKVRDGARSL VQDDSLLKYL SLARDTLWPG
GVLRKAPPRS VADRLNSRAE ATVVLATLIP DLAGNVVGRA NAQAAARRIF ATLNNQHLNT
HLVFTILDEI VLVLFGSSGR SREK
//
