ID A0A135LZL4_PENPA Unreviewed; 666 AA.
AC A0A135LZL4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Terpene cyclase/mutase family member {ECO:0000256|RuleBase:RU362003};
DE EC=5.4.99.- {ECO:0000256|RuleBase:RU362003};
GN ORFNames=PGRI_075460 {ECO:0000313|EMBL:KXG54402.1};
OS Penicillium patulum (Penicillium griseofulvum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes;
OC Eurotiomycetidae; Eurotiales; Aspergillaceae; Penicillium.
OX NCBI_TaxID=5078 {ECO:0000313|EMBL:KXG54402.1, ECO:0000313|Proteomes:UP000070168};
RN [1] {ECO:0000313|EMBL:KXG54402.1, ECO:0000313|Proteomes:UP000070168}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PG3 {ECO:0000313|EMBL:KXG54402.1,
RC ECO:0000313|Proteomes:UP000070168};
RX PubMed=26729047; DOI=10.1186/s12864-015-2347-x;
RA Banani H., Marcet-Houben M., Ballester A.R., Abbruscato P.,
RA Gonzalez-Candelas L., Gabaldon T., Spadaro D.;
RT "Genome sequencing and secondary metabolism of the postharvest pathogen
RT Penicillium griseofulvum.";
RL BMC Genomics 17:19-19(2016).
CC -!- SIMILARITY: Belongs to the terpene cyclase/mutase family.
CC {ECO:0000256|RuleBase:RU362003}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXG54402.1}.
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DR EMBL; LHQR01000013; KXG54402.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135LZL4; -.
DR STRING; 5078.A0A135LZL4; -.
DR OMA; FAWEDEK; -.
DR OrthoDB; 2785544at2759; -.
DR Proteomes; UP000070168; Unassembled WGS sequence.
DR GO; GO:0005811; C:lipid droplet; IEA:InterPro.
DR GO; GO:0016866; F:intramolecular transferase activity; IEA:InterPro.
DR GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR GO; GO:0016104; P:triterpenoid biosynthetic process; IEA:InterPro.
DR CDD; cd02892; SQCY_1; 1.
DR Gene3D; 1.50.10.20; -; 2.
DR InterPro; IPR006400; Hopene-cyclase.
DR InterPro; IPR032696; SQ_cyclase_C.
DR InterPro; IPR032697; SQ_cyclase_N.
DR InterPro; IPR018333; Squalene_cyclase.
DR InterPro; IPR008930; Terpenoid_cyclase/PrenylTrfase.
DR NCBIfam; TIGR01507; hopene_cyclase; 1.
DR NCBIfam; TIGR01787; squalene_cyclas; 1.
DR PANTHER; PTHR11764; TERPENE CYCLASE/MUTASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11764:SF82; TERPENE CYCLASE_MUTASE FAMILY MEMBER; 1.
DR Pfam; PF13243; SQHop_cyclase_C; 1.
DR Pfam; PF13249; SQHop_cyclase_N; 1.
DR SFLD; SFLDG01016; Prenyltransferase_Like_2; 1.
DR SUPFAM; SSF48239; Terpenoid cyclases/Protein prenyltransferases; 2.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU362003};
KW Reference proteome {ECO:0000313|Proteomes:UP000070168};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transferase {ECO:0000313|EMBL:KXG54402.1}.
FT DOMAIN 21..319
FT /note="Squalene cyclase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13249"
FT DOMAIN 328..659
FT /note="Squalene cyclase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13243"
SQ SEQUENCE 666 AA; 74181 MW; 38A65D08770ED182 CRC64;
MNLQNESDGS SLVSQVEHAL KLSTDYALGL VHPDGHWYGE MNANVTVTAE YIFLRQAFGL
DLKADAIAYC RYLLSQQNSD GSWGLAPEHP GDVSTSTEAY LALKILGTSP HIPAMRRARA
FVLEAGGIAR VRVFTRIFLA TFGLFPWDAV PELPVELMLL PSICPINIYT FASWARGTIA
PLLIICHHRP VYSLPNGKSA TNDYLDELWL DCTSKSVPYG QPLWDLLSQR EFAGSAFGVL
DKILYQLNGL RSIPLVRAYA RKQCIKWILE RQEKTGDWAG IFPPMHASMY AFTLEGYKLN
DDPVQLGFQA LEQFAWEDEK GKRIQACVSP VWDTALMTIG FCDAMSPNQQ AIDKALKWIR
ARQLLEPRGD WRVYRPQLAP GGFSFEYENS WYPDVDDTAA IILAQVKDDS GSIGSDSVIA
AATWILGMQN PDGGWAAFDV ENDKLFLNKI PFSDMDSLCD TSCADITGRI LEAFGLMMKC
SSGKADAGLM LLPLRAACAR GVQYLVSTQK PNGSWFGRWG CNYIYGTSHA LCGLAYFGDE
SRVRVIVKPA LQWLKSRQND DGGWGESVLS YKLPDEEKQA STPSQTAWAL MGLLSHLPVT
DDAIESGIQY LVSSQKPEKG IGSSWPQVVY TGTGFPNHFY LGYDYYRHYF PMMALGRYLQ
GTQRLH
//
