ID A0A135T6Q2_9PEZI Unreviewed; 673 AA.
AC A0A135T6Q2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Major facilitator superfamily (MFS) profile domain-containing protein {ECO:0000259|PROSITE:PS50850};
GN ORFNames=CSAL01_03978 {ECO:0000313|EMBL:KXH43816.1};
OS Colletotrichum salicis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1209931 {ECO:0000313|EMBL:KXH43816.1, ECO:0000313|Proteomes:UP000070121};
RN [1] {ECO:0000313|EMBL:KXH43816.1, ECO:0000313|Proteomes:UP000070121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 607.94 {ECO:0000313|EMBL:KXH43816.1,
RC ECO:0000313|Proteomes:UP000070121};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum salicis CBS 607.94.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily.
CC Monocarboxylate porter (TC 2.A.1.13) family.
CC {ECO:0000256|ARBA:ARBA00006727}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH43816.1}.
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DR EMBL; JFFI01002089; KXH43816.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135T6Q2; -.
DR OrthoDB; 1969303at2759; -.
DR Proteomes; UP000070121; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 3.90.210.10; Heat-Labile Enterotoxin, subunit A; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR001144; Enterotoxin_A.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR11360; MONOCARBOXYLATE TRANSPORTER; 1.
DR PANTHER; PTHR11360:SF321; MONOCARBOXYLATE TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G12710)-RELATED; 1.
DR Pfam; PF01375; Enterotoxin_a; 1.
DR Pfam; PF07690; MFS_1; 1.
DR PRINTS; PR00771; ENTEROTOXINA.
DR SUPFAM; SSF56399; ADP-ribosylation; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070121};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Toxin {ECO:0000256|ARBA:ARBA00022656};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Virulence {ECO:0000256|ARBA:ARBA00023026}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..673
FT /note="Major facilitator superfamily (MFS) profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007803310"
FT TRANSMEM 233..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..298
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..328
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 367..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 564..589
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 601..621
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 633..654
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..659
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
SQ SEQUENCE 673 AA; 72837 MW; 9F5B48C9874F7567 CRC64;
MARQQPLVLG PTLIAFWAFL CNSLDLHRAD SRPYATIQAS KGFLPKGQST FGVAAPDTSL
WNHVNGASTG FSKDEDGYVS TTSDRNLAET WVNRFLGGNG FVYRIHSAPN MIDCQGTLQK
YNPYPQEAEF AALGGIKDNQ IIGWTPVRGG VKGKEELNPF YQGNIYSNMG TGGSQYKLAA
FPPNHPAWGE APWSQFSSCT RRRSARDLFQ IEKRACSASK SNVDYAKEYL DRYIIVVLAA
FMISFMTGGL QFGFGIYQAH YETMALEDDT PLTSATAARL DLIGTLAISM MTICAPVVVA
WSKIIVPQKV MCAGGLLVGV ANVLASFGRE LWHYQITQGF LMGVGSCLSF VLSMVVVPTW
FDKHRALAMD IVSAGSSVGG LVWAPVLVAC IEKLGYRNTL RMTGTLGAVV VCVCGAMLTW
TPAMAARIRS EKMTTSRLKK MFKVPLPPGK TVKQRKFIAQ SFSMFCQSAA YYTPAFFFAS
YAKTLGYSDS DGANLTAVNN ACNAVGKIAI GLVADRIGRL NALFLMTVIC AAVTIGSWVS
SIAIGMSHED SGYPGFVTQG RSLLVSFTVL YGIFASAYVS LFPPALIGLF GMELMPQITG
IMYMIMGVAS MIGTPVAGAL VRGHGEIKES GDYMGMGIMV GTLMAAAEIF VAWMRLEATA
DRAQGGRKWV WKL
//
