ID   A0A135TCF3_9PEZI        Unreviewed;       394 AA.
AC   A0A135TCF3;
DT   06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT   06-JUL-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   RecName: Full=nitrilase {ECO:0000256|ARBA:ARBA00039045};
DE            EC=3.5.5.1 {ECO:0000256|ARBA:ARBA00039045};
GN   ORFNames=CSAL01_02005 {ECO:0000313|EMBL:KXH45843.1};
OS   Colletotrichum salicis.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC   Colletotrichum acutatum species complex.
OX   NCBI_TaxID=1209931 {ECO:0000313|EMBL:KXH45843.1, ECO:0000313|Proteomes:UP000070121};
RN   [1] {ECO:0000313|EMBL:KXH45843.1, ECO:0000313|Proteomes:UP000070121}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS 607.94 {ECO:0000313|EMBL:KXH45843.1,
RC   ECO:0000313|Proteomes:UP000070121};
RA   Baroncelli R., Thon M.R.;
RT   "The genome sequence of Colletotrichum salicis CBS 607.94.";
RL   Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a nitrile + 2 H2O = a carboxylate + NH4(+);
CC         Xref=Rhea:RHEA:21724, ChEBI:CHEBI:15377, ChEBI:CHEBI:18379,
CC         ChEBI:CHEBI:28938, ChEBI:CHEBI:29067; EC=3.5.5.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00036406};
CC   -!- SIMILARITY: Belongs to the carbon-nitrogen hydrolase superfamily.
CC       Nitrilase family. {ECO:0000256|ARBA:ARBA00008129}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXH45843.1}.
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DR   EMBL; JFFI01002028; KXH45843.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A135TCF3; -.
DR   STRING; 1209931.A0A135TCF3; -.
DR   OrthoDB; 1361256at2759; -.
DR   Proteomes; UP000070121; Unassembled WGS sequence.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:InterPro.
DR   CDD; cd07564; nitrilases_CHs; 1.
DR   Gene3D; 3.60.110.10; Carbon-nitrogen hydrolase; 1.
DR   InterPro; IPR003010; C-N_Hydrolase.
DR   InterPro; IPR036526; C-N_Hydrolase_sf.
DR   InterPro; IPR044149; Nitrilases_CHs.
DR   PANTHER; PTHR46044:SF1; CN HYDROLASE DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR46044; NITRILASE; 1.
DR   Pfam; PF00795; CN_hydrolase; 1.
DR   SUPFAM; SSF56317; Carbon-nitrogen hydrolase; 1.
DR   PROSITE; PS50263; CN_HYDROLASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000070121}.
FT   DOMAIN          13..303
FT                   /note="CN hydrolase"
FT                   /evidence="ECO:0000259|PROSITE:PS50263"
SQ   SEQUENCE   394 AA;  43207 MW;  BE64616F00EB8CB0 CRC64;
     MNSQVHGDPH EPVKVAVVQA EPCWFDVEAA TQKTCDLIAE AGANSAKLIA FPELWIPGYP
     NFIHAMAAKE TFPYNIKYYR NSIDIESKHM EKIRLAVKNA QIMCVLGISE RHHGSLYMAQ
     TFIGPHGDIL LHRRKFKPTA QEGILFGDAS GDCTTNVVST PIGRVGGLQC FEHLQPLLKY
     NTYFQGEQIH VASWPNLFPP VGKMPFFNTV ESCTMATHTM AVEGATFVLL ASSTQTEKGL
     VANGLIPSQD TDDAKNAPAD TEERPHIAVI GGGFSEIIAP DGRTLVKAPS ATFEGLLYGE
     LDFDKIYMTK SIVDTVGQYS RPDIFTLQGA MSGASATTLS LANSTMPRGC RKCLLTKDFR
     MKAGLGGPKP SKSWLNFHPI WRYNVLLVTE YTAC
//