ID A0A135UHZ6_9PEZI Unreviewed; 4372 AA.
AC A0A135UHZ6;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=Dynein heavy chain, cytoplasmic {ECO:0000256|ARBA:ARBA00022197};
DE AltName: Full=Dynein heavy chain, cytosolic {ECO:0000256|ARBA:ARBA00033439};
GN ORFNames=CNYM01_08159 {ECO:0000313|EMBL:KXH60009.1};
OS Colletotrichum nymphaeae SA-01.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1460502 {ECO:0000313|EMBL:KXH60009.1, ECO:0000313|Proteomes:UP000070054};
RN [1] {ECO:0000313|EMBL:KXH60009.1, ECO:0000313|Proteomes:UP000070054}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SA-01 {ECO:0000313|EMBL:KXH60009.1,
RC ECO:0000313|Proteomes:UP000070054};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum nymphaeae SA-01.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Consists of at least two heavy chains and a number of
CC intermediate and light chains. {ECO:0000256|ARBA:ARBA00011655}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH60009.1}.
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DR EMBL; JEMN01000563; KXH60009.1; -; Genomic_DNA.
DR Proteomes; UP000070054; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR CDD; cd00009; AAA; 2.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF314; CYTOPLASMIC DYNEIN 1 HEAVY CHAIN 1; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 1959..2097
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2616..2771
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2958..3124
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 1662..1689
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3206..3297
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3446..3487
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 4372 AA; 495905 MW; DD4F07CD44DE87B3 CRC64;
MEVASTPIPG ANGVTSPTAE SSIDPSRVLD HIALVCQIAL GATNEDLESP GSLLHKHRYS
DTVQRCTRFA TDTPNALYIQ KDILPVSTIQ NGTEDSSSFN PREAEPLTAC IGTANRLSVE
SPSYTYSLTT EISSSPTTVS CLVLLKQRPG PIDPSLPLTS QILLTNLPGP ATLNATAGEQ
GPSTSPFEIL HSYVHNALAP YFDANTRSQI TNGARGRADV DSKTGIPVTK KRWNDLELSL
LHLQQNVEIP EVSLMFHTMV QNALEEADSR HSKPTLDLIP GTVLSDSTFL NSLQNNVNSW
IKSIQVITRM TRDPADSAKD FKFTASQEVN FWLSMESALE GIEGQLRSEG VLLTLEILKH
AKRFQATVSF TADTGLKEAM EKVQKYNQLM RDFPLDELLS ATYLSKVKDA IVQIFGHLNR
KLRICPYPIR RALPLVEAIS GDLDEVLHRL LPGTELVNLD YTEFKAIMKA SDDIFTTWDE
SIKEFTNVAR EVTRRRNEKF IPIKVNPKHA ELQGRLKYVS TFRDNHEQLQ RTIVNVLGPK
ATVSGLTETT NTNGVVVVEE MGDVDAVEEV KQAWEALKNV DLLDVSPEGT ERWAKAENMY
NERTSRVENS IIARLRDRLA TAKNANEMFR VFSKFNALFV RPKIRGAIAE YQNQLMEHVK
QAIHGLHERF KQQYGHSEAH AMAQLRDLPP VSGAIIWARQ IEHQLDNYMK KVEDVLGSEW
AIHAEGQKLQ SESNLFRKKL DTQTIYKAWL DDVQRRQISI SGFLFDIRRQ RSTGNSYELM
VNFDPQVITL FKETRNLMWQ NYAVPHSINN VSKDAKRVYP FAVSLMESVR TFSQTMRQIS
EMGEEAVLVY GYKNDVYALV SRGVPLRWES FVNSHEIFFS TKNNATLPNV SEFGLSKPSE
SKHSLFIREF AAAVSLLQAK TASLASIHAT VEKALIELNT CPYEASAFTS RLETIQTAVD
QLNLEQYVNL PFWVDMMNQK LKEVLLTRLQ DAILAWINAF EDDYLDDGRR KQVTENGEEA
VQEGPTIKRL ILELSMRNQV IYLDPPLEYS RSSWFVQLHE WLGIVCNLKK IKATRYQMTL
TTTTLDEPHF DDLPSDCTDL LSRVYVSVEK KLQEIGSYVD KWLQFQSLWD LQSEQVYEAL
GDQLARWLQL LQEIRKTRQT FDTQEVSRQF GHITIDYDQV QTKVNAKYDQ WQHEILMKFA
SRLGNRMREV HAEIEKARRD LESQGLDASS TAQAVQFITV VQACRRNVKL WAPEIDMFRQ
GQSTLVRQRY QFPNDWLHIE QIDSSWESLT EILEKKSKIV QDQTDALRSK IIAEDKIVND
RIAEVAVQWN DEKPVSGTTQ PDVATATLKT FETRISKLQS DFEMVAKAKE ALDIPTSTDS
SLATILEEVQ DFQSVWSNLS TIWASLNETR EVLWTAVQPR KIRSKIDDLI KSTKEMPSRM
RQYAAFEHVQ TILRSLLKVN TILSDLKSEA IRDRHWTKIY KQIKPGKRYS PVSMTLGDVW
DLNLVATEVI VRDIIAQAQG EMALEEFLKQ VRETWSNYGL ELVNYQNKCR LIRGWDDLFA
KCSENLNSLQ AMKHSPYYKE FEEEASSWED KLNRVHVLFD VWIDVQRQWV YLEGVFTGNA
DIKHLLPVES SRFQNINSEF SAVMKKVYKQ PYVLDVLTIP NVQKSLERLA ELLNKIQKAL
GEYLEKERVS FPRFYFVGDE DLLEMIGNSN DTLRIAKHFK KMFAGLSGLI MDDETIISGF
TSKEGEAVRL KKEISLAKTP KINDWLALLE SGMKNTLAEL LAEAVEQYTP IFESEKIDKE
AMDAFMEAFP SQIVVLATQV VWTTSVEKSL VDGGKSLQSL YELEVQVLRL LADTVLGDLE
VIQRKKCEQL ITECVHQRDA IEKLISLNAT SPTHYWWLLQ MRYVYTPEGD FPNRLQVKMA
NAKLSYGFEY LGVPERLVRT PLTDRCFLTL TQALEQRLGG SPYGPAGTGK TESVKALGLQ
LGRFTLVFCC DDTFDFQAMG RIFLGICQVG AWGCFDEFNR LEERILSAVS QQIQNIQLGL
KKGAEDEKAQ TELVGRQLHV NANTGIFITM NPGYAGRSNL PDNLKKLFRS VAMSKPDKEL
IAEVMLYSQG FNQAKQLSKH TVPFFDQCAA RLSKQAHYDF GLRALKSVLV SSGGLKRARL
VESDGSIGAE EVVEPEIIVQ SIRETIAPKL IKSDVEILGE VEEDCFPGVK YVPANLQALE
EAIRTLADER KLVVNDTWMT KVLQLYQIQK IHHGVMMVGN SGTGKSAAWT LLLDALQKVE
GVEGVQHVID SKVMSKEALY GNLDSTTREW TDGLFTSILR KIVDNLRGED SKRHWIVFDG
DVDPEWVENL NSVLDDNKLL TLPNGERLNL PANVRIMFEV ETLKYATLAT VSRCGMVWFS
EDTVTPMMML EHYLGTLRSK PFEDLDEDSV AAGQSPAKAL AVQSQVADLL NAYLSGEDFL
TAALKEAESY NHIMDFTVAR VLNTLFSLLN KAVRDIIEYN AQHSDFPLDP EQVEAYIAKK
LLLALVWALT GDCPLNDRKA FGDAVGGLAS FGNPPLDGSS SLIDFDVSLP QAEWTPWQNQ
VPTIEVNTHS VTQTDVVIPT LDTVRHEDVL YSWLAEHKPL LLCGPPGSGK TMTLFSALRK
LPNMEVVGLN FSSATTPDLL IKTFEQYCEY KKTLNGVMLS PTQIGRWLVI FCDEINLPAP
DKYGTQRAIS FLRQLVEHNG FWRTSDKSWV TLDRIQFVGA CNPPTDAGRT PLGARFLRHA
PLIMVDYPGE LSLLQIYGTF NSAVLKIIPS LRGYSEPLTQ AMVKLYLESQ KRFTPKIQPH
YVYSPRELTR WVRGIYEAIR PLETLSIEGL VRIWAHEALR LFQDRLVAED ERQWTDDAVR
RIALDLFPTI DDQKALGGPI LFSNWLSKNY VPVDREQLRD FVKARLKTFC EEEVDVPLIL
FNDVLEHVLR IDRVFRQPQG HLILIGVSGS GKTTLSRFVA WMNGLKVFQI KVHGKYSAED
FDDDLRDVLR RCGCKGEKIC FIMDEANVLD SGFLERMNTL LANAEVPGLF EGDEFAALMT
ACKEGAQRQN LHLDSPEELY KWFTQQIVKN LHVVFTMNPP EGGLGSKAAT SPALFNRCVL
NWFGDWSDQA LFQVGHELTQ SMDLDRPNFQ APDTIPVAYR ALSLPPTHRE TIVNSMVYIH
YSLQRFNTKL FKQQGKVTFL TPRHFLDFVA QYVKLYNEKR EDLEEQQRHL NVGLEKLRDT
VDKVRDLRVS LAEKKSQLEK KDAEANEKLQ RMVADQREAE QRKNTSLEIQ VALEKQEAEV
ASRRTVVLED LAKAEPAVEE AKASVSNIKR QHLTEVRSMG NPPQGVRLAL ESVCALLGHK
VNDWRTIQGI IRRDDFIASI VNFDNERQMT KALRTKMRND FLSIPEFTFD KVNRASKACG
PLVQWVEAQV LYSEILDRVG PLRDEVDALE ETALQTKAEA KAVENTINTL ESSIAQYKTE
YAALISETQA IKSEMSKVQF KVDRSVKLLD SLSSERVRWE EGSKSFETQI STLVGDVLVA
AAFLAYGGLY DQTFRKSMMD DWLHQLQLSG VLYKQHNPVT EYLSTADERL SWQENSLPVD
DLCTENAIVL KRFNRYPLII DPSGRVTEFL QKESKDRRLT VTSFLDDSFT KQLESSLRFG
NPILIQDAEY LDPILNHVLN KEYQKTGGRV LIQLGKQQID FSPSFKIYLS TRDPSATFAP
DICSRTTFVN FTVTQSSLQT QSLNDVLKSE RPDVDERRSN LIKLQGEFKI HLRQLEKRLL
QALNESRGNI LDDDNVIETL ETLKTEAAEI SDKMSNTEGV MAEVEEITQQ YSIIARSCST
VFAVLEQLHY LNHFYQFSLQ YFLDIFHSVL HGNKNLANET NHNIRRDIIV KDLFITAFKR
TALGLLQKDR ITLAMLLAQA SPYKMDKTLI DVILDDRVEG KDLSTDKDAK EEAFTRAGRM
SVLKDKLDAV PSADWDKFLT EELAENFVPQ IWDDSTEAFD QALQSLLLVK LFRLDRFVPA
AERFVTLVFG SDTFDVVEDL KETVSQVPAT RPISLVSSPG FDASYKVDNL VERLRVKCTN
IAMGSNEGLA SADKAINNAA QLGNWVLVKN VHLAPTWLQS LEKRMESLNP HSEFRLFLSM
ESSPKIPVNL LRASRVLMYE QPAGVRANMK DSMSSLSTRG AKAPVERTRL YLLLAFLHAV
VQERLRYAPS LGWKGFWEFN DSDYECSAFI IDTWIENAAG TRTNIAPQSI PWEMIRYLVT
ETYGGKIDNE GDFKQLNQLV HSFLTPSAYD VGHKLVEGTE NQEGSLVVPS GTSLSDFMAW
IHKLPEREPP TYLGLPANAE KLLLVGLGRS LIGNLKRVTE LLEEGEQLMV EA
//
