ID A0A135V1S2_9PEZI Unreviewed; 611 AA.
AC A0A135V1S2;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Beta-hexosaminidase {ECO:0000256|PIRNR:PIRNR001093};
DE EC=3.2.1.52 {ECO:0000256|PIRNR:PIRNR001093};
GN ORFNames=CSAL01_04419 {ECO:0000313|EMBL:KXH66581.1};
OS Colletotrichum salicis.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Glomerellales; Glomerellaceae; Colletotrichum;
OC Colletotrichum acutatum species complex.
OX NCBI_TaxID=1209931 {ECO:0000313|EMBL:KXH66581.1, ECO:0000313|Proteomes:UP000070121};
RN [1] {ECO:0000313|EMBL:KXH66581.1, ECO:0000313|Proteomes:UP000070121}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 607.94 {ECO:0000313|EMBL:KXH66581.1,
RC ECO:0000313|Proteomes:UP000070121};
RA Baroncelli R., Thon M.R.;
RT "The genome sequence of Colletotrichum salicis CBS 607.94.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Hydrolysis of terminal non-reducing N-acetyl-D-hexosamine
CC residues in N-acetyl-beta-D-hexosaminides.; EC=3.2.1.52;
CC Evidence={ECO:0000256|ARBA:ARBA00001231,
CC ECO:0000256|PIRNR:PIRNR001093};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 20 family.
CC {ECO:0000256|ARBA:ARBA00006285, ECO:0000256|PIRNR:PIRNR001093}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXH66581.1}.
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DR EMBL; JFFI01000641; KXH66581.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A135V1S2; -.
DR STRING; 1209931.A0A135V1S2; -.
DR OrthoDB; 178991at2759; -.
DR Proteomes; UP000070121; Unassembled WGS sequence.
DR GO; GO:0004563; F:beta-N-acetylhexosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0102148; F:N-acetyl-beta-D-galactosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 3.30.379.10; Chitobiase/beta-hexosaminidase domain 2-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR025705; Beta_hexosaminidase_sua/sub.
DR InterPro; IPR015883; Glyco_hydro_20_cat.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR029018; Hex-like_dom2.
DR InterPro; IPR029019; HEX_eukaryotic_N.
DR PANTHER; PTHR22600; BETA-HEXOSAMINIDASE; 1.
DR PANTHER; PTHR22600:SF56; BETA-HEXOSAMINIDASE; 1.
DR Pfam; PF00728; Glyco_hydro_20; 1.
DR Pfam; PF14845; Glycohydro_20b2; 1.
DR PIRSF; PIRSF001093; B-hxosamndse_ab_euk; 1.
DR PRINTS; PR00738; GLHYDRLASE20.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF55545; beta-N-acetylhexosaminidase-like domain; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PIRNR:PIRNR001093};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PIRNR:PIRNR001093};
KW Reference proteome {ECO:0000313|Proteomes:UP000070121};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..611
FT /note="Beta-hexosaminidase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5007805708"
FT DOMAIN 21..194
FT /note="Beta-hexosaminidase eukaryotic type N-terminal"
FT /evidence="ECO:0000259|Pfam:PF14845"
FT DOMAIN 219..558
FT /note="Glycoside hydrolase family 20 catalytic"
FT /evidence="ECO:0000259|Pfam:PF00728"
FT ACT_SITE 380
FT /note="Proton donor"
FT /evidence="ECO:0000256|PIRSR:PIRSR001093-1"
SQ SEQUENCE 611 AA; 68186 MW; 6C264AA8BCCB48BB CRC64;
MLPSLLLVSL SLAMGQVSAG IWPAPKKLST GKSVLFISQT LEITYNGGSV RWRPSSASTS
TSHDETQNTE NFFNVQLPYI YGYNPASGST FNSKDIVQGG VSRAMAAIFQ QNFVPWKYHP
KNSDFEPDVY AADKKAVKSL QITQTGEDKP STFKPVAGEV DESYALNITE DGSATLVAKS
SIGVLRGLET FVQLFYQHTS GTSWYTTLAP VSIEDSPEYS HRGIMIDTAR NFFPVEDVLR
VIDAMSWNKL NRLHIHITDS QSWPLDIPAM PDLAAKGAYR KGLSYSPEDL AKIQEYAVHR
GIEPVIEIDM PGHIGSVSFA YPELIVAYNE KPYTWWCVEP PCGAFKMNDT RVDDFLDKLF
DDLLPRVGPY TAYFHTGGDE LNKNDSMLDE GIRSNSSEVL QPLLQKFMDK NHARIRKHGL
IPLVWEEMPL EWNITLGDDV VIQSWLGGDS VKKLTSNGHK VIDSNYNYWY SDCGRGHWMN
FDNGAAFEAF FPFNDWCSPA KGWRLMYSHD PRANLTEAEA KLVLGGEVAA WSESIDPVSI
DGILWPRASA AGEVLWSGRR DASGQNRSQY DAAPRLAEFR ERMVARGVRS EPVQMPFCTQ
GDAGECGYPM V
//
