ID A0A136HC98_9GAMM Unreviewed; 1001 AA.
AC A0A136HC98;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=Diguanylate cyclase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AXW15_09740 {ECO:0000313|EMBL:KXJ53281.1};
OS Neptuniibacter sp. Phe_28.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Neptuniibacter.
OX NCBI_TaxID=1795871 {ECO:0000313|EMBL:KXJ53281.1, ECO:0000313|Proteomes:UP000070472};
RN [1] {ECO:0000313|Proteomes:UP000070472}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Dombrowski N., Donaho J.A., Gutierrez T., Seitz K.W., Teske A.P.,
RA Baker B.J.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXJ53281.1}.
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DR EMBL; LSMR01000144; KXJ53281.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136HC98; -.
DR Proteomes; UP000070472; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 2.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 2.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 2.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 2.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..35
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 294..314
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 326..396
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 399..451
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 448..494
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 519..573
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 605..738
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 747..1001
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 1001 AA; 112711 MW; 35DEBC13B45FFA11 CRC64;
MKDYKVINPQ SISNWIFAGV LSSILLIGSV LWFSLIQSIT ERTERSVLHA RMIESTVTRT
FEALEISLHS LSDDLKGGEL SPSHLQSLRE KALKILAFAP QLRQIVIVKD SNTLIDTQQS
QPQNINLSIL GLQAPSPHAY SLGLHIGTAL HGRFLPLRDS YPDESIKLEF IPIGFWTRTN
AGEKVLIVAT FNSHYVKRYI TDLQLDDNNQ VYLTDFQGNA LLQTGLYGPN RENVIAHLTT
ILHSGKDEGV STTAYDILPL NITTTRLLTK YPLSVSIVTD FKGSFAVWIE QKRIFLLILG
AAIATLIIGT VYIVRINNSA LEMKEEVHLL SEVVENNPTV IIITNREGQI QYVNNSFEAI
SGYKKDEVLG QTSRMFKSGE MSEQEYAAMS RTLNTGNSWH GELQSKRKDG RFYWERASIS
PLINDHNEIT HFIALKQEIT EEKEFQDKLR LASDVFNTAA EAILITDKNN RIQMVNPSFQ
KITGYSEADV LGKTPSLLKS GKHSPEFYEN IYNQLKTHHL WEGEIWNKRK NGEVYPEWLV
ISSRFDLDGN IEGYVALFSD ITKRKRDQAV ITHQANYDAL TGLPNRNLFE DRLIQSKTLC
DRNKTEAALL FLDLDRFKYV NDTFGHIAGD TLLKLVATRL TACIRKSDTV ARLGGDEFAI
IIPELSSAIL VEKIAKKILS SLTEPFVLDG NHAYISCSIG IVVHTNDNIS LEELIYNADS
AMYKAKTKGR NRYEFFDEAL NAKNRERNLL EKDIYCAIER NEFHLVYQPI WSIDGQHIHS
IEALIRWQHP TRGLISPADF IPITEESGQI IAIGEWVIKE ACKFARKISL EGGTPPSISV
NISSAQFMKG GVVEIIKREL ENNNLKGANL IAEITENLLL SDQEDIYLQL KNIVALGVEL
AIDDFGTGYS SLSYLKKYPI KRLKVDKIFI DEIVTDVDDL ALVSGILSLA NSLSLSTVIE
GVETQAQLAT LKKLGSPMIQ GYLFSRPIKE EQMLELLRNN V
//
