ID A0A136ISM6_9PEZI Unreviewed; 553 AA.
AC A0A136ISM6;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=Putative alpha/beta fold family hydrolase {ECO:0000313|EMBL:KXJ87806.1};
GN ORFNames=Micbo1qcDRAFT_124295 {ECO:0000313|EMBL:KXJ87806.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ87806.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; KQ964261; KXJ87806.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136ISM6; -.
DR STRING; 196109.A0A136ISM6; -.
DR InParanoid; A0A136ISM6; -.
DR OrthoDB; 203032at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0006082; P:organic acid metabolic process; IEA:UniProt.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR InterPro; IPR002204; 3-OH-isobutyrate_DH-rel_CS.
DR InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR InterPro; IPR013328; 6PGD_dom2.
DR InterPro; IPR006115; 6PGDH_NADP-bd.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR000073; AB_hydrolase_1.
DR InterPro; IPR029154; HIBADH-like_NADP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR PANTHER; PTHR22981; 3-HYDROXYISOBUTYRATE DEHYDROGENASE-RELATED; 1.
DR PANTHER; PTHR22981:SF81; DEHYDROGENASE, PUTATIVE-RELATED; 1.
DR Pfam; PF00561; Abhydrolase_1; 1.
DR Pfam; PF14833; NAD_binding_11; 1.
DR Pfam; PF03446; NAD_binding_2; 2.
DR SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00895; 3_HYDROXYISOBUT_DH; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000313|EMBL:KXJ87806.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501}.
FT DOMAIN 3..30
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 34..141
FT /note="6-phosphogluconate dehydrogenase NADP-binding"
FT /evidence="ECO:0000259|Pfam:PF03446"
FT DOMAIN 147..259
FT /note="3-hydroxyisobutyrate dehydrogenase-like NAD-binding"
FT /evidence="ECO:0000259|Pfam:PF14833"
FT DOMAIN 306..537
FT /note="AB hydrolase-1"
FT /evidence="ECO:0000259|Pfam:PF00561"
SQ SEQUENCE 553 AA; 60018 MW; 44FD929097902878 CRC64;
MSSIGFIGLG TMGYPMALNL ATKMPKVMLY VNDDILITIV PEGSHVRQVY LDEMNGVIAA
NLNNKILIDC STIDTETSAH VAAEIRTQDQ TASFYDAPIS GGSLGAENAT LTFMVGCSEL
DASWPTLDKL LGLMGTSIFA CGAPTLGLTA KLSNNYCSAL IALATAEAMN IGMKAGMDPR
VLATIFSKST AQSTICDKWC PVPGVVPTAP SSHGYKGGFK VQLMKKDFTL AMAAANLVEA
KTYLGGVGLG VYSAAAEDPK CRDLDSRVVF RFIGGNEHWA ESTHSSGQLS HYIIDDFTDP
WKKSDVVLIQ HGFGRTVHHW YHWVPALARR YVVIRRDLRG HGLSTCPKAT DNYDYSLETI
LAEIIDMLDQ LRIDKVHFLG ESTSGMLGEA LAVRFPHRLH SLVICSSPTH LPPPALEFFA
FGHADWPTAC RKLGSRGWAE VLSKEPGTGP TADLGYKAWW LREIAKSSGE GLAGYAEFLS
RLDARPFLKG IKIPVLILAP NDSAVMTVEA MEDVARQIEG SILQVVRAQG HEIYVTGADE
CQEAVLEFWA SLK
//
