ID A0A136J9E3_9PEZI Unreviewed; 589 AA.
AC A0A136J9E3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Major facilitator superfamily domain-containing protein {ECO:0000313|EMBL:KXJ93780.1};
GN ORFNames=Micbo1qcDRAFT_201733 {ECO:0000313|EMBL:KXJ93780.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ93780.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. Sugar
CC transporter (TC 2.A.1.1) family. {ECO:0000256|ARBA:ARBA00010992}.
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DR EMBL; KQ964247; KXJ93780.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136J9E3; -.
DR STRING; 196109.A0A136J9E3; -.
DR InParanoid; A0A136J9E3; -.
DR OrthoDB; 1056225at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 2.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR005828; MFS_sugar_transport-like.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR23511; SYNAPTIC VESICLE GLYCOPROTEIN 2; 1.
DR PANTHER; PTHR23511:SF5; TRANSPORTER, PUTATIVE (AFU_ORTHOLOGUE AFUA_2G03500)-RELATED; 1.
DR Pfam; PF00083; Sugar_tr; 2.
DR SUPFAM; SSF103473; MFS general substrate transporter; 1.
DR PROSITE; PS50850; MFS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 53..82
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 118..139
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 159..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 193..218
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 396..416
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 489..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 519..538
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 53..541
FT /note="Major facilitator superfamily (MFS) profile"
FT /evidence="ECO:0000259|PROSITE:PS50850"
FT REGION 568..589
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 575..589
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 589 AA; 64342 MW; 207E774961DFB289 CRC64;
MALLSAIMLA IHKLLKYWEP LRLEGDIGQV RNRQRREARV LQILEGIGFS WRIYFVAFFG
FLASSWSLIA INITMPALIY VYDLQDQFGL HLDIATLVGT VLGMIIFGIV ADQVGRSALY
GFELLIVLAA IGGAAFSSQG YTSPVSNTHH SMDMNAALIW WRFALGLGIG AEYPMSAVIA
AEFTSTAWRG TMLAAIFIAQ PVGRLLAYGL SMAIIAGYTG RTAEPTDAEM KITADSVWRL
VLGLAGAPAV FAVALRFFIP ETPRFYSAVK RDHRKAIEVA LRLGSASTRS ADTESLDSDE
LDEQLVPNQP RASWRTSAWA YLFGTSQGWK RLFAITLQWL LLDVCFCGTG LDSPSTLAAL
WLDKAGIEPA HIWNEDPGHP NADIYSVLAA NSRRTLLTTS IAALLGSVCA IPLVGFVSRK
SLYVITSAVL AMMFAANAIA IHKTYAQPSH VASIVFYALT QFLFNVGPNT LTFVIAVEIF
PTEFRGTCYG IAAAGGKVGA IIIRPIVAQM GEKNDKNLPV LLGIFAIIMA IMAILAWIEP
FGIGFPLIQQ LEKDEQWSRR LNNLSLEEIS PWPPSEDEEE RQQAEAAAG
//
