ID A0A136JI60_9PEZI Unreviewed; 2043 AA.
AC A0A136JI60;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=SH3 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=Micbo1qcDRAFT_129833 {ECO:0000313|EMBL:KXJ96831.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ96831.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC ProRule:PRU00983}.
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DR EMBL; KQ964245; KXJ96831.1; -; Genomic_DNA.
DR STRING; 196109.A0A136JI60; -.
DR InParanoid; A0A136JI60; -.
DR OrthoDB; 8258at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd08679; C2_DOCK180_related; 1.
DR CDD; cd11684; DHR2_DOCK; 1.
DR Gene3D; 1.25.40.410; -; 1.
DR Gene3D; 2.60.40.150; C2 domain; 1.
DR Gene3D; 1.20.1270.350; Dedicator of cytokinesis N-terminal subdomain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR027007; C2_DOCK-type_domain.
DR InterPro; IPR035892; C2_domain_sf.
DR InterPro; IPR026791; DOCK.
DR InterPro; IPR043161; DOCK_C_lobe_A.
DR InterPro; IPR032376; DOCK_N.
DR InterPro; IPR042455; DOCK_N_sub1.
DR InterPro; IPR027357; DOCKER_dom.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR PANTHER; PTHR45653:SF10; MYOBLAST CITY, ISOFORM B; 1.
DR Pfam; PF14429; DOCK-C2; 1.
DR Pfam; PF16172; DOCK_N; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS51650; C2_DOCK; 1.
DR PROSITE; PS51651; DOCKER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 3: Inferred from homology;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 7..87
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 586..765
FT /note="C2 DOCK-type"
FT /evidence="ECO:0000259|PROSITE:PS51650"
FT DOMAIN 1414..1836
FT /note="DOCKER"
FT /evidence="ECO:0000259|PROSITE:PS51651"
FT REGION 92..158
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 375..471
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1748..1779
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1837..1866
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1896..2017
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 375..419
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 431..446
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 448..471
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1758..1777
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1838..1866
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1922..1937
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1965..1980
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2043 AA; 226927 MW; 3122DF4A58485050 CRC64;
MPWQPLPRIA FAVATYPFAP LGEHDLPLEI GDDLYIIEET PNGQWLRGYL LAPPSLTAGL
TSVKGQTLEA RVFSGIFPRS CVEIRELLGE ADDISSSDDD EADSDERASS AGDHGEPRFG
TTDDALRTKP APQRVPGEPK PAAPVPMLRI GDESPTSASE PLIDEIASCL REWHSTNFHE
LLLSRQYGSL DKVSQIIQAL DLARRQFLHN VLTTHEYDAL REKTVWNLVR GNKLCGGEVI
VRDPKQRGRV LTGEDSVVEI TKLQSVMSLL DEPPVVHAET TALHHLMVDI KSFAGSSNEP
TTLLLSLVSR SIGGTVTTLS ESYVIEIPAG GLMGNNSRDG QLRTLFMDLT SGDIGDAPSA
DSELFLVVKV RAPQQISTGK PSSRSGSFSQ PATPFSKEKP PPSSGTKASR RSLMWGSTRS
AFSRAGGKLD ALSEQPEERP QTDRVESRDG QVPPSTAGSR GPRPSSDGTQ VTHMSVDKLV
GMGVLKINSI MQQPDEVEHV VTIWSATSQS SFDTQHDEDC DILVKSLLDS KSGHYEKSRR
AERLQVHLKP FNYPDPDALI KATPTLLSGI SKTPKMGFPG APTKPRSDIY ITLHQAHLGR
QNLLSRFGGS ATALPSSMHG NNLTVTLEVR SQSGERIENC IYSASNAEAV STWRSFAAER
SERWNQCLRL ALSPDEVMTS HVMVTMTDLP NQPFAVGYLP LWEQHAFVND GVHSLLLYKL
DENTRTAQPG PTGQGGYLTV PWGPRIDSSE VTGPLATLRI ESYLCSTRFS QDRVILGLLK
WKDVPKDEIP GLLRQVTFVP EIEIVKLLNE VLDALFGVLV DNQENDEYED LVFAALVRVL
DIIHDRRFNL GPLVDHYAEN KFNYPFATAC LVRSLTRLLS KPTEPETARK LRATLKVVRY
ILKFVTHARD QQKAKEAGIG IVNGNPGFTR HLQNIFKALD SMMRSTAPVL VGSQTLAVQH
FHTWLPELTG LLTTEEILHI AIDFIDSCAL VKGKLILYKL VLIINYAKLA LFSQPEQRSA
LCANTIRWIA PHWGQTLEVT EQWKDQVRLC CSIVASQADH LGPEVPDYIP KITDSFRAIQ
AAGVQSKNKL SLLFPASYPF PAKNMGGDAV RFDESLIELS AVLSALSSSP AGLQLELTED
DLASVLKNTL QVHMSILQGE AFPSSWLSVH IFHHKSTMKT LQYLASIMLE QFLPHPDDAE
SFDTELWKMF FTTLLKLVGS ECLALETFPE QKRRAVWKIA GDVREHGAEL LRRTWEAIGW
ETSSDERSRY GLSKMGGYQV QYVPSLVGPI VELCLSVHEG LRRMAVEVLQ TMIVSEWTLS
DDLSVIQTEM IDCLDRFFKD KAMTESILQK LFVQELLDRF EPLSHIEDDA MYAGLRDLIA
TVDEFLDLLV AVHSGEVTGQ ASNLINRLRL MEFLRDMQKE EIFIRYVHQL AHLQAEARNH
TEAGLALKLH AELYEWDPTR NTRSLHDPDM PEQSHFERKE RIYFDMIKHF EDGEAWSSAL
AAYKELQAQY ENNVFDFAKL ARAERAIATI YETLAKSERL VPKYFKVVYK GLGFPTTLRD
KAFICEGSPN ERTTAFTDRM QGQYQAAQII TSGDVDSDTE GQFLVVSSVS PHRDLGHPVF
QRARVQQPIR DYLLSAHPQM FSVSSKRNTT GPVATHHAEK TVYTTAESFP TILRRSEIVD
IETVQLGAKE TGLERIVRKT QEMTAVEKRL DDGDEEVAQL FIDAIRISVT ADSDSSVVGY
RELLPKPQHK SKELGNLDSD DDDSDDDGSD EGEVELDEQE NAIKMALVDH AIMLKRCLSS
FARSSNPVLR KAYQDLHMHY ESTFAPEIAV FTPAAAPRDL QNTPSPTWQR SPRLTDSPPR
GQLSSSVSKG IVEEAASVQP INLRQRGAAR LSFLGGKRKE SHSSAGGGDV SGSPQLNGDS
DAGHGGDHHK TKDHGHRMSF FNTTSGENIH TPNHQHHREQ SNGFSHHRTS PSASTTQDRG
LKSRDIIDVV EKGIDAQGNS HSSEGQHGEG GLMKKASIRK RFSTLKLGTK KSKNALMGDV
REE
//
