ID A0A136JIA7_9PEZI Unreviewed; 811 AA.
AC A0A136JIA7;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Carnitine O-acetyltransferase, variant 2 {ECO:0000313|EMBL:KXJ96881.1};
GN ORFNames=Micbo1qcDRAFT_142636 {ECO:0000313|EMBL:KXJ96881.1};
OS Microdochium bolleyi.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Xylariomycetidae; Xylariales; Microdochiaceae; Microdochium.
OX NCBI_TaxID=196109 {ECO:0000313|EMBL:KXJ96881.1, ECO:0000313|Proteomes:UP000070501};
RN [1] {ECO:0000313|Proteomes:UP000070501}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=J235TASD1 {ECO:0000313|Proteomes:UP000070501};
RG DOE Joint Genome Institute;
RA David A.S., May G., Haridas S., Lim J., Wang M., Labutti K., Lipzen A.,
RA Barry K., Grigoriev I.V.;
RT "Draft genome sequence of Microdochium bolleyi, a fungal endophyte of
RT beachgrass.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the carnitine/choline acetyltransferase family.
CC {ECO:0000256|ARBA:ARBA00005232}.
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DR EMBL; KQ964245; KXJ96881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136JIA7; -.
DR STRING; 196109.A0A136JIA7; -.
DR InParanoid; A0A136JIA7; -.
DR OrthoDB; 1429709at2759; -.
DR Proteomes; UP000070501; Unassembled WGS sequence.
DR GO; GO:0016746; F:acyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 2.
DR Gene3D; 1.10.275.20; Choline/Carnitine o-acyltransferase; 1.
DR Gene3D; 3.30.559.70; Choline/Carnitine o-acyltransferase, domain 2; 1.
DR InterPro; IPR000542; Carn_acyl_trans.
DR InterPro; IPR042572; Carn_acyl_trans_N.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR039551; Cho/carn_acyl_trans.
DR InterPro; IPR042231; Cho/carn_acyl_trans_2.
DR PANTHER; PTHR22589; CARNITINE O-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR22589:SF29; MITOCHONDRIAL CARNITINE O-ACETYLTRANSFERASE-RELATED; 1.
DR Pfam; PF00755; Carn_acyltransf; 1.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 2.
DR PROSITE; PS00440; ACYLTRANSF_C_2; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315};
KW Fatty acid metabolism {ECO:0000256|ARBA:ARBA00022832};
KW Lipid metabolism {ECO:0000256|ARBA:ARBA00023098};
KW Reference proteome {ECO:0000313|Proteomes:UP000070501};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:KXJ96881.1};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 21..657
FT /note="Choline/carnitine acyltransferase"
FT /evidence="ECO:0000259|Pfam:PF00755"
FT REGION 542..592
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 675..710
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 725..746
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..577
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..692
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 725..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT ACT_SITE 327
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600542-1"
SQ SEQUENCE 811 AA; 89426 MW; 82A12FA8A2037A48 CRC64;
MAEASRPAGI TFAGQDQLPR LPIPSLDKTC HKYLAALKPL QDPREHAETT LAVHEFLHHD
GPQLQAKLLE YAKDKVSYIE QFWYDSYLNF DNPVVLNLNP FFLLEDDPTP ARNNQVTRAA
SLVVSALEFV RAVRREELPP DMLKGKPLDM YQYSRLFGTA RVPSSHGCQI EQDPDSKHVV
VICHGQFYWF DVLDDNSDLI MTEKDISINL QTIVNDAAQT PIQEAAKGAL GVLSTENRKI
WSQMRDTLTR EEGSNNADCL GIIDSALFVL CLDYTEPLTA AALCQNMLCG TNDVQKGVQI
GTCINRWYDK LQIIVCKNGS AGINFEHTGV DGHTVLRFAS DVYTDTILRF ARTINGQAPS
LWKTTSPDPS KRDPESFGDV TTSPHKLEWD MIPELNVAVR FAETRLADLI GQTEFECLDF
SGYGKNFITS SGFSPDAFVQ MAFQAAYYGL YGRVECTYEP AMTKMFLHGR TEAVRSVTEA
SVEFIQNFWG DNPEEQKVAA LRKACQQHVD NTRESAKAEG CDRHLYALYT IWQKAMEEFH
SSTTVTPADE SSSDSGPDDI ARDPAVESEE RNRAGSNSSR SREPPLMPRV FSDGGWEKLN
QTILSTSNCG NPSLRQFGFG PTSGDGFGIG YIIKDEGINV CVSSKHRQTK RFLDTLESYL
LEIQRVLRVI NRRTSANSKQ SRAREIDDPR DAVGKSIGAS AGAPPRGLKA RGRMISSGLE
NLRALTRPSQ SDLKSQASEE GPATTDDGLG GYGFFDAGML LHALKARSAT SAAGGTAIDG
GGGPQVLGNS SAAAHVRRRG DIGKKLRLVE Y
//
