ID A0A136LPX9_9CHLR Unreviewed; 676 AA.
AC A0A136LPX9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=Chloride channel protein {ECO:0000313|EMBL:KXK23647.1};
GN ORFNames=UZ15_CFX003000596 {ECO:0000313|EMBL:KXK23647.1};
OS Chloroflexi bacterium OLB15.
OC Bacteria; Chloroflexota.
OX NCBI_TaxID=1617416 {ECO:0000313|EMBL:KXK23647.1, ECO:0000313|Proteomes:UP000070332};
RN [1] {ECO:0000313|EMBL:KXK23647.1, ECO:0000313|Proteomes:UP000070332}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLB15 {ECO:0000313|EMBL:KXK23647.1};
RA Speth D.R., In T Zandt M., Guerrero Cruz S., Jetten M.S., Dutilh B.E.;
RT "Genome based microbial ecology of anammox granules in a full-scale
RT wastewater treatment system.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK23647.1}.
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DR EMBL; LMZS01000028; KXK23647.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136LPX9; -.
DR STRING; 1617416.UZ15_CFX003000596; -.
DR Proteomes; UP000070332; Unassembled WGS sequence.
DR GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR CDD; cd02205; CBS_pair_SF; 1.
DR CDD; cd00400; Voltage_gated_ClC; 1.
DR Gene3D; 3.10.580.10; CBS-domain; 1.
DR Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR Gene3D; 3.30.70.1450; Regulator of K+ conductance, C-terminal domain; 1.
DR InterPro; IPR000644; CBS_dom.
DR InterPro; IPR046342; CBS_dom_sf.
DR InterPro; IPR014743; Cl-channel_core.
DR InterPro; IPR001807; Cl-channel_volt-gated.
DR InterPro; IPR006037; RCK_C.
DR InterPro; IPR036721; RCK_C_sf.
DR PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR Pfam; PF00571; CBS; 2.
DR Pfam; PF02080; TrkA_C; 1.
DR Pfam; PF00654; Voltage_CLC; 1.
DR PRINTS; PR00762; CLCHANNEL.
DR SMART; SM00116; CBS; 2.
DR SUPFAM; SSF54631; CBS-domain pair; 1.
DR SUPFAM; SSF81340; Clc chloride channel; 1.
DR SUPFAM; SSF116726; TrkA C-terminal domain-like; 1.
DR PROSITE; PS51371; CBS; 2.
DR PROSITE; PS51202; RCK_C; 1.
PE 4: Predicted;
KW CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 27..45
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 65..88
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 204..222
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..259
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 280..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 343..363
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..399
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 406..423
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 461..520
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 525..582
FT /note="CBS"
FT /evidence="ECO:0000259|PROSITE:PS51371"
FT DOMAIN 590..672
FT /note="RCK C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51202"
SQ SEQUENCE 676 AA; 72450 MW; 91ADA98B9C578851 CRC64;
MQKIFSRQSG SWFDAFTAPL RAEKNRLVAL AIAVGVVTAL GVWLFREAII FFRQLFFGVL
VDQLLSPIVG VLAVVISLAL GGFIVGWIMQ HCIGEERHHG VGGVIEAVAL AGGRLRYKRM
PFKALASAIS NGAGASVGPE DPSVQIGGNI GSWLGQLARQ SEEHVAILVA AGSAAAISAA
FKAPFAGVFF AVEAILNNSM EARSLSVVVL AAVMSFATTQ AIEPGYDMGP FAFSLSGALE
ILAFAPLGLL IALSAVLFLR HSRWQHRLWH RVKLSRPVKT ALVGVVVGVV GIFLPEVLGQ
GHDIVDHVLM GDLQFSILML VVIGLVKIIV TGISLGGGFV GGLFAPSIFI GTMLGSAYGH
VIAALPGINS ADPRAYGIAG MAAMVAAVIR APITAILLVF ELTNDFTLIV PLMLVTIVCL
MVAERFEPFG VYVFGLRAKG VFLPEGREVD LMQGVLVEDV MQRPAPTIQP TAELRELRDK
LRAYESGALC VVDEAGNLRG IVTLVDLQKA YEAQAEPGTT VGQIASQGVI TITPGEPAWR
AIRLMNRNDI RQLPVIDFDT GKLLGVVGRR EIIQAYQTAT TRRMQDQQTA ERIRLNTLTG
GLSKEYRVSA HSAVNNKHVR EVNWPVNSIV ASIERDGRIL IPHGETVLQG NDVLTIVAAR
TVEENLKALI ERDAAQ
//
