ID A0A136MRR1_9BACT Unreviewed; 1396 AA.
AC A0A136MRR1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=UZ16_OP3001001500 {ECO:0000313|EMBL:KXK36527.1};
OS Candidatus Hinthialibacteria bacterium OLB16.
OC Bacteria; Candidatus Hinthialibacterota.
OX NCBI_TaxID=1617433 {ECO:0000313|EMBL:KXK36527.1, ECO:0000313|Proteomes:UP000070296};
RN [1] {ECO:0000313|EMBL:KXK36527.1, ECO:0000313|Proteomes:UP000070296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLB16 {ECO:0000313|EMBL:KXK36527.1};
RA Speth D.R., In T Zandt M., Guerrero Cruz S., Jetten M.S., Dutilh B.E.;
RT "Genome based microbial ecology of anammox granules in a full-scale
RT wastewater treatment system.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK36527.1}.
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DR EMBL; LMZT01000071; KXK36527.1; -; Genomic_DNA.
DR STRING; 1617433.UZ16_OP3001001500; -.
DR PATRIC; fig|1617433.3.peg.1620; -.
DR Proteomes; UP000070296; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.40.50.2300; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 4.
DR InterPro; IPR011006; CheY-like_superfamily.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR007895; MASE1.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013655; PAS_fold_3.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR001789; Sig_transdc_resp-reg_receiver.
DR NCBIfam; TIGR00229; sensory_box; 4.
DR PANTHER; PTHR43065:SF10; PEROXIDE STRESS-ACTIVATED HISTIDINE KINASE MAK3; 1.
DR PANTHER; PTHR43065; SENSOR HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF05231; MASE1; 1.
DR Pfam; PF08447; PAS_3; 2.
DR Pfam; PF13426; PAS_9; 2.
DR Pfam; PF00072; Response_reg; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00086; PAC; 4.
DR SMART; SM00091; PAS; 1.
DR SMART; SM00448; REC; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF52172; CheY-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 4.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50113; PAC; 4.
DR PROSITE; PS50112; PAS; 1.
DR PROSITE; PS50110; RESPONSE_REGULATORY; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553, ECO:0000256|PROSITE-
KW ProRule:PRU00169};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 42..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 88..111
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 123..144
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 156..184
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 196..215
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 251..273
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 395..447
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 529..581
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 663..715
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 718..785
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 788..840
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 1030..1255
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT DOMAIN 1277..1393
FT /note="Response regulatory"
FT /evidence="ECO:0000259|PROSITE:PS50110"
FT MOD_RES 1328
FT /note="4-aspartylphosphate"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00169"
SQ SEQUENCE 1396 AA; 155911 MW; A7C078887E03FBDF CRC64;
MRIHASTMNP FLRFILVVIS SFAGYLACSR ISLMLLTQPE NISAFWPPVG ILFGLLMVIP
RLHWAGILTG SFCGNVVANM LIGKSFPISF IFSIGDLGFA YLFSELAVRY LGRPVTLNSL
REIFHILGLG GFGISTGCAT WGALTLWLNQ PVESFWLLWA CWWSADIMGI LIFTPVCLAL
IPGGYREIRS MNRARILEGC ALLAVFSLLV LGIFGNRYES TRILGPLPFT FVPVLLISAI
RFGVRGAALT TSAFGISSVI FTVNGFGPFA SIFHSASEAI FRLQAFLAIS NVSTLVVAGS
IAERKKSLDD LARTERLYRK AIEIAGAVPY FGLYGKKDFE FVGEGIDKLT GIPASRFDHQ
KLADITLEIH PLGELNGKNA DDAIETVREH HEIPWHADYR IQLPDGDIRW LANSAVQVLD
GKGNAIGSLG ILQDITERKK SEQAIARSEE LYRSAIDGAG AVPYYRDYKT DARGEILSSR
YSFMGKGIER ITGYTPEEFT LELFEEILTD EIRYNPASAP GQSEIQPQFR AEYALRHKNG
SICWVSDAAV DIHNEQGHFI ASLGILQDIT LRRQAEEEIR KTDLLYRSAI EGADAVPYYL
NHRTVAYDFL GDGILNLTGF SSKEFTPEVF QTLILDRVFH AEMRGLTREQ AMHRMRTEIG
SCWRADYRIK TRHGEERWIS DSAVQVLDDK KNVIGSLGIL MDITDRRKSE DSIRIRDRAL
SFALNGIMIT DASVPENPIM FVNPAFTKIT GYQLEDMAGK TPYFLYEHGD HQEGLDIIRR
AFTEGTAAEA VSPINRKDGQ TIWGDIFIAP VRNDMDQVTH FICIQNDITD RMRIEKDQKV
LIDGLRSIVG IADELLDCPD EDTITRMAVE LGRERLGMER LAFHRMENET LFGTYGTDAQ
GNTIDEKSYK KQFDRKWFEA LKIETGSNYQ WYYIDGGHYS WNNGEMDQIG SGWVVMTPVA
SSQKWQGVFF NDTALSGKPY DPTRQELLAV YASLFSNIIE RRRSEEARSK LEAQVHHTQK
LESLGVLAGG IAHDFNNLLM GVLGNASLAL MELPPESPAR ESVNHIEKAA MRAAELARQM
LAYSGKGRFV IQKINLSKLV EEMTHLLQVS ISKKVFLRYN FADNLPAIEG DATQIRQVIM
NLITNASDAI GDKSGVITIT TGLIETDSTY LESTYLKDDL PGGYYVFLEV SDTGCGMDEE
TRARIFDPFF TTKFTGRGLG LAAVLGIVRG HKGTVKVYSE AGRGTTFKIL LPCCDSQEDT
QENHVESTRK DWVGTGTILI VDDEESVRYI SKRILESHGF KVLTANDGRE GVKAYEAQKE
AIDLVLLDMT MPHMDGEEAF RELRLINPDV HVILTSGYTE QEATARFTGK GLAGFIQKPF
LPSSLLEIVR NKLSTS
//
