ID A0A136MSM0_9BACT Unreviewed; 416 AA.
AC A0A136MSM0;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE RecName: Full=Citrate synthase {ECO:0000256|PIRNR:PIRNR001369};
GN Name=gltA {ECO:0000313|EMBL:KXK36857.1};
GN ORFNames=UZ16_OP3001001326 {ECO:0000313|EMBL:KXK36857.1};
OS Candidatus Hinthialibacteria bacterium OLB16.
OC Bacteria; Candidatus Hinthialibacterota.
OX NCBI_TaxID=1617433 {ECO:0000313|EMBL:KXK36857.1, ECO:0000313|Proteomes:UP000070296};
RN [1] {ECO:0000313|EMBL:KXK36857.1, ECO:0000313|Proteomes:UP000070296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OLB16 {ECO:0000313|EMBL:KXK36857.1};
RA Speth D.R., In T Zandt M., Guerrero Cruz S., Jetten M.S., Dutilh B.E.;
RT "Genome based microbial ecology of anammox granules in a full-scale
RT wastewater treatment system.";
RL Submitted (NOV-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+);
CC Xref=Rhea:RHEA:16845, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16452, ChEBI:CHEBI:16947, ChEBI:CHEBI:57287,
CC ChEBI:CHEBI:57288; EC=2.3.3.16;
CC Evidence={ECO:0000256|ARBA:ARBA00000308};
CC -!- PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle.
CC {ECO:0000256|ARBA:ARBA00005163}.
CC -!- SIMILARITY: Belongs to the citrate synthase family.
CC {ECO:0000256|ARBA:ARBA00010566, ECO:0000256|PIRNR:PIRNR001369,
CC ECO:0000256|RuleBase:RU003406}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK36857.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; LMZT01000064; KXK36857.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A136MSM0; -.
DR STRING; 1617433.UZ16_OP3001001326; -.
DR PATRIC; fig|1617433.3.peg.1430; -.
DR UniPathway; UPA00223; -.
DR Proteomes; UP000070296; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0036440; F:citrate synthase activity; IEA:UniProtKB-EC.
DR GO; GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-UniPathway.
DR CDD; cd06118; citrate_synt_like_1; 1.
DR Gene3D; 1.10.580.10; Citrate Synthase, domain 1; 1.
DR Gene3D; 1.10.230.10; Cytochrome P450-Terp, domain 2; 1.
DR InterPro; IPR011278; 2-MeCitrate/Citrate_synth_II.
DR InterPro; IPR016142; Citrate_synth-like_lrg_a-sub.
DR InterPro; IPR016143; Citrate_synth-like_sm_a-sub.
DR InterPro; IPR002020; Citrate_synthase.
DR InterPro; IPR019810; Citrate_synthase_AS.
DR InterPro; IPR024176; Citrate_synthase_bac-typ.
DR InterPro; IPR036969; Citrate_synthase_sf.
DR NCBIfam; TIGR01800; cit_synth_II; 1.
DR PANTHER; PTHR11739; CITRATE SYNTHASE; 1.
DR PANTHER; PTHR11739:SF4; CITRATE SYNTHASE, PEROXISOMAL; 1.
DR Pfam; PF00285; Citrate_synt; 1.
DR PIRSF; PIRSF001369; Citrate_synth; 1.
DR PRINTS; PR00143; CITRTSNTHASE.
DR SUPFAM; SSF48256; Citrate synthase; 1.
DR PROSITE; PS00480; CITRATE_SYNTHASE; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000313|EMBL:KXK36857.1};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR001369}.
FT ACT_SITE 296
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
FT ACT_SITE 352
FT /evidence="ECO:0000256|PIRSR:PIRSR001369-1"
SQ SEQUENCE 416 AA; 46099 MW; 0F04D587A6558ACB CRC64;
MKKYIEEIVR QAKVRARQES DAEPEPGLIS PVQWPVNCDV KQGLEGAITG QTEIGYVNGP
KGWLIYRGLD CFDLSEHSTF EETSYLLLFG KLPSKTEMDE FMAKLNSYRT LPDEALRLLD
SLPVKSAHPM STLRTIVSAL GMMDPNSDVT TVKAETEVAI KLIAQIVTIT GAIARIRKGE
KPLAPDTSLS LAADLVRMMT GKMPNEEDAR IMDICLILHA DHGMNASTFS AMVVNSSLSD
MYSSIVAGIA SLKGPLHGGA NEAVLADLEE IGSVDNVQAW YSLSKVGKRR VMGFGHRVYK
AYDPRARILH PLAELLSRRD PNVRRLYDTA AELEKWVVGD LGKEKGIFPN VDFYSGIVYT
AMGIEKAMFT PIFAVSRMSG WGARALEYLK NNRIFRPRAV YVGPLHVEYV PIEERS
//
