ID   A0A136NMH5_9BACT        Unreviewed;       271 AA.
AC   A0A136NMH5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=3-hydroxyacyl-CoA dehydrogenase nad-binding protein {ECO:0000313|EMBL:KXK47293.1};
GN   ORFNames=UZ05_CHB002002248 {ECO:0000313|EMBL:KXK47293.1};
OS   Chlorobi bacterium OLB5.
OC   Bacteria; Chlorobiota.
OX   NCBI_TaxID=1617412 {ECO:0000313|EMBL:KXK47293.1, ECO:0000313|Proteomes:UP000070057};
RN   [1] {ECO:0000313|EMBL:KXK47293.1, ECO:0000313|Proteomes:UP000070057}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OLB5 {ECO:0000313|EMBL:KXK47293.1};
RA   Speth D.R., In T Zandt M., Guerrero Cruz S., Dutilh B.E., Jetten M.S.;
RT   "Genome based microbial ecology of anammox granules in a full-scale
RT   wastewater treatment system.";
RL   Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXK47293.1}.
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DR   EMBL; LLZO01000265; KXK47293.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A136NMH5; -.
DR   Proteomes; UP000070057; Unassembled WGS sequence.
DR   GO; GO:0070403; F:NAD+ binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0044248; P:cellular catabolic process; IEA:UniProt.
DR   GO; GO:0006631; P:fatty acid metabolic process; IEA:InterPro.
DR   GO; GO:1901575; P:organic substance catabolic process; IEA:UniProt.
DR   Gene3D; 1.10.1040.50; -; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR022694; 3-OHacyl-CoA_DH.
DR   InterPro; IPR006180; 3-OHacyl-CoA_DH_CS.
DR   InterPro; IPR006176; 3-OHacyl-CoA_DH_NAD-bd.
DR   InterPro; IPR006108; 3HC_DH_C.
DR   InterPro; IPR008927; 6-PGluconate_DH-like_C_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR48075; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   PANTHER; PTHR48075:SF5; 3-HYDROXYACYL-COA DEHYDROGENASE FAMILY PROTEIN; 1.
DR   Pfam; PF00725; 3HCDH; 1.
DR   Pfam; PF02737; 3HCDH_N; 1.
DR   PIRSF; PIRSF000105; HCDH; 1.
DR   SUPFAM; SSF48179; 6-phosphogluconate dehydrogenase C-terminal domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR   PROSITE; PS00067; 3HCDH; 1.
PE   4: Predicted;
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002}.
FT   DOMAIN          1..172
FT                   /note="3-hydroxyacyl-CoA dehydrogenase NAD binding"
FT                   /evidence="ECO:0000259|Pfam:PF02737"
FT   DOMAIN          175..271
FT                   /note="3-hydroxyacyl-CoA dehydrogenase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00725"
FT   SITE            128
FT                   /note="Important for catalytic activity"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000105-1"
SQ   SEQUENCE   271 AA;  29665 MW;  B6507C005F68EB94 CRC64;
     MGSGIAAASA ISGFSTFLYD LFPESVDKAF SAIKKGWQKL EEKGKLNADK RNAAEGNLQK
     AAELEGLADC DIIIEAAVEN IELKKDLYKK LDKISKPEAI LATNTSSFSI TSISTAVKNN
     PGRVIGMHFF NPANIMKLVE VIKGEFTSED TVIAVAELCK KMGKVPVLCK DTPAFIVNRV
     ARAFYGESLK ILGEESLDPA LIDTIMKEEG SFAMGPFELM DLIGIDVNLS VTKSVYEAFF
     YDQKYKPSPI QQKMVDSGLL GRKTGQGFYK Y
//