ID   A0A136PRP3_9ACTN        Unreviewed;       520 AA.
AC   A0A136PRP3;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Aminopeptidase {ECO:0000313|EMBL:KXK60994.1};
GN   ORFNames=AWW66_16010 {ECO:0000313|EMBL:KXK60994.1};
OS   Micromonospora rosaria.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=47874 {ECO:0000313|EMBL:KXK60994.1, ECO:0000313|Proteomes:UP000070620};
RN   [1] {ECO:0000313|EMBL:KXK60994.1, ECO:0000313|Proteomes:UP000070620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 803 {ECO:0000313|EMBL:KXK60994.1,
RC   ECO:0000313|Proteomes:UP000070620};
RA   Yang H., He X., Zhu D.;
RT   "Whole genome sequence and analysis of Micromonospora rosaria DSM 803,
RT   which can produce antibacterial substance rosamicin.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M28 family. M28A subfamily.
CC       {ECO:0000256|ARBA:ARBA00005957}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXK60994.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; LRQV01000053; KXK60994.1; -; Genomic_DNA.
DR   RefSeq; WP_067366488.1; NZ_LRQV01000053.1.
DR   AlphaFoldDB; A0A136PRP3; -.
DR   OrthoDB; 345880at2; -.
DR   Proteomes; UP000070620; Unassembled WGS sequence.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0008235; F:metalloexopeptidase activity; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:InterPro.
DR   CDD; cd03876; M28_SGAP_like; 1.
DR   Gene3D; 2.60.120.200; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR045175; M28_fam.
DR   InterPro; IPR041756; M28_SGAP-like.
DR   InterPro; IPR007484; Peptidase_M28.
DR   PANTHER; PTHR12147; METALLOPEPTIDASE M28 FAMILY MEMBER; 1.
DR   PANTHER; PTHR12147:SF55; PEPTIDE HYDROLASE; 1.
DR   Pfam; PF04389; Peptidase_M28; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000313|EMBL:KXK60994.1};
KW   Hydrolase {ECO:0000313|EMBL:KXK60994.1};
KW   Protease {ECO:0000313|EMBL:KXK60994.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070620};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           25..520
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5039683072"
FT   DOMAIN          112..330
FT                   /note="Peptidase M28"
FT                   /evidence="ECO:0000259|Pfam:PF04389"
SQ   SEQUENCE   520 AA;  52337 MW;  012D6F73CE42E85A CRC64;
     MRSRTPWIAV LASAAVTLAT ATGAAPAPRS APAPAPTALA APTVLAAPDI PVANVQAHLN
     QFLSIATANG GNRAHGRPGY LASVNYVKGR LDAAGYTTTV QSFTYNGATG YNLIADWPGG
     DPNAVVMTGA HLDSATAGPG INDNGTGSAA ILEVALAVAR TGFSPDKHLR FAWWGAEELG
     LRGSRHYVTA LPAAERTKIK AYLNFDMVGS PNPGYFVYDG DNSDGVGAGP GPAGSAQIEQ
     TLQAYFTSIG VPTRGTDFDG RSDYGPFISA GIPAGGTFTG AEGTKTSAQV ALWGGTAGAA
     FDPCYHRACD NLGNVNATAL DRNTDAIAYT VWALAGAAPP PGTTVHTDGF ETATGWTVNP
     AGTDTATSGR WERGVPAATS SGGVSTQLAA ATGSYALVTG AAAGAAAGDN DLDGGVSTIQ
     SGPITLPATG TLTLSLAAYL AHLTNATSAD YLRVRVVGTS TVTALNLTGA AVNRAAAWQT
     TSTDITALRG QTVRIVVDAA DAGTASLVEA AVDDVRIVQS
//