ID   A0A136PSG5_9ACTN        Unreviewed;       929 AA.
AC   A0A136PSG5;
DT   08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT   08-JUN-2016, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=LuxR family transcriptional regulator {ECO:0000313|EMBL:KXK61411.1};
GN   ORFNames=AWW66_13825 {ECO:0000313|EMBL:KXK61411.1};
OS   Micromonospora rosaria.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Micromonospora.
OX   NCBI_TaxID=47874 {ECO:0000313|EMBL:KXK61411.1, ECO:0000313|Proteomes:UP000070620};
RN   [1] {ECO:0000313|EMBL:KXK61411.1, ECO:0000313|Proteomes:UP000070620}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 803 {ECO:0000313|EMBL:KXK61411.1,
RC   ECO:0000313|Proteomes:UP000070620};
RA   Yang H., He X., Zhu D.;
RT   "Whole genome sequence and analysis of Micromonospora rosaria DSM 803,
RT   which can produce antibacterial substance rosamicin.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXK61411.1}.
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DR   EMBL; LRQV01000042; KXK61411.1; -; Genomic_DNA.
DR   RefSeq; WP_067365347.1; NZ_LRQV01000042.1.
DR   AlphaFoldDB; A0A136PSG5; -.
DR   OrthoDB; 134933at2; -.
DR   Proteomes; UP000070620; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd06170; LuxR_C_like; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR   PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF00196; GerE; 1.
DR   PRINTS; PR00038; HTHLUXR.
DR   SMART; SM00421; HTH_LUXR; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS00622; HTH_LUXR_1; 1.
DR   PROSITE; PS50043; HTH_LUXR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070620}.
FT   DOMAIN          844..910
FT                   /note="HTH luxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50043"
FT   REGION          906..929
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   929 AA;  96382 MW;  116E7B5A9F62E3E5 CRC64;
     MSGATVGRQP EIDRVRHALG EGRPVLVEGP AGIGKTALHR AVLAGVADDG WTVLGCAPTE
     TEAALPFAAL ADVLSPLADL VPDLPVPQRT AVTGVLLSGE VTDPVDERTV GVATRALLDA
     AARARPDTRL LVAVDDAPWL DAPSERALRF ALRRLGSRVG VLATARADPP GADPAPLGLA
     HAGVLRVALG PLGVGPLHHV LRAEVGATLP RPLLVRIARD AGGNPLLAIE LARAVLRLPQ
     LPAPGADLPA GPSLRHLVAD RLAALPPPTR RAIRLAALCG TPTLADLARC DVPATALDAA
     EEAGLVAVAE QRITFTHPVY AAAVRAGIPP GVRRGLHQVL AGTVTDPDER ARHLAACATA
     PDPDAAERIA AAAARHRARG AAEAAAGLYD TAARLTPRTD PDGYAHRRLA AAGCRFDSGD
     YPAAALAADR AAAELTGTGR AEALLLRSVV AWCAEDLSTS LSAADLALSA APAGSPVAGR
     VHAHLALYRD APDPARRHAE QAVALLAASP ADRAVHAAAL LLLFFNEVRA GLPARTDLLE
     RALRLEGDEP SWLAGTVPAV WWKGVDEHDR SRERLRWMLD RAVARGDEPS QHELLTHLGE
     TELFAGRWPA AAAHLTAARE LGEQSGVEPV GADWLAGLLA AAQGRLAEAN RTAEAGLRRA
     DELADGWRRR IHQQLAGFAA LCGGAYAVAA GHYGALAATV DGMGLAEPLA QRFEADWLEA
     CVGAGDLGTA EAALERLAAR HRRLPRPWTT LGLARSRVLL AGARGRDPGD ALADLVAARA
     AVPAGVVPLE RAWCLLVAGV AYRRVRRRRE ARAALTTAAL EFDALGAAGL AARSRAEAAR
     LGGRPPAPRE LTGTELAVAR LAAAGRTNRV IADTLFISPK TVEANLARIY RKLGVASRAE
     LGAAMAREPG PVPAAGPRTV PAGGPGGDR
//