ID A0A136PVP9_9ACTN Unreviewed; 487 AA.
AC A0A136PVP9;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:KXK62482.1};
GN ORFNames=AWW66_07945 {ECO:0000313|EMBL:KXK62482.1};
OS Micromonospora rosaria.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47874 {ECO:0000313|EMBL:KXK62482.1, ECO:0000313|Proteomes:UP000070620};
RN [1] {ECO:0000313|EMBL:KXK62482.1, ECO:0000313|Proteomes:UP000070620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 803 {ECO:0000313|EMBL:KXK62482.1,
RC ECO:0000313|Proteomes:UP000070620};
RA Yang H., He X., Zhu D.;
RT "Whole genome sequence and analysis of Micromonospora rosaria DSM 803,
RT which can produce antibacterial substance rosamicin.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FMN; Xref=ChEBI:CHEBI:58210;
CC Evidence={ECO:0000256|ARBA:ARBA00001917};
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK62482.1}.
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DR EMBL; LRQV01000018; KXK62482.1; -; Genomic_DNA.
DR RefSeq; WP_067361994.1; NZ_LRQV01000018.1.
DR AlphaFoldDB; A0A136PVP9; -.
DR OrthoDB; 3396880at2; -.
DR Proteomes; UP000070620; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR PANTHER; PTHR11780:SF10; NADH DEHYDROGENASE [UBIQUINONE] FLAVOPROTEIN 1, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11780; NADH-UBIQUINONE OXIDOREDUCTASE FLAVOPROTEIN 1 NDUFV1; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13459; Fer4_15; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000070620}.
FT DOMAIN 316..361
FT /note="NADH-ubiquinone oxidoreductase 51kDa subunit iron-
FT sulphur binding"
FT /evidence="ECO:0000259|SMART:SM00928"
SQ SEQUENCE 487 AA; 50346 MW; 772E3B39AC1ACEB7 CRC64;
MRTTVPPVAC VGEPRLTAGF AEFGRLDLYA HEQVHGPIGP MEPANLLGLA EAIQLKGKGG
AGFPLAKKLR AVLESCERQD LSPVVVVNAT EGEPASWKDK VLLTRAPHLI LDGAALAAYA
LDAEEIVIGV ADDDIGRESL TLALEERPMP VDTSIVTVPH RFISGEGGAL VNGINGLPHI
PPGTKKRSSD SGVNGLPTLL SNAETYAQLA VAARLGPYEY AALGTDDEPG TVLLTVTGAA
ARQAVVECAA GTPLREILDL CEVPEGPGIL MGGYHGKWIT SAAADMAEVS RKGLAAVGGT
LGAGIIVPLG KDTCPLGEAA QVVRYLAGES AGQCGPCKMG LPDLARAVDL AVSGSAPVEI
VRAAAGDVKG RGACSHPDGT ARFALSAMEV FADDLRLHTT GEGCGRRVKG VMGLPGAPDG
NPQKLTLDWS RCDGHGLCAH VVPDFIRLDA NGYPAFPPTP VPTWLREGAQ KAVKVCPELA
LRLVKAT
//
