ID A0A136PVR8_9ACTN Unreviewed; 705 AA.
AC A0A136PVR8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=ATP-dependent DNA helicase {ECO:0000313|EMBL:KXK62495.1};
GN ORFNames=AWW66_08045 {ECO:0000313|EMBL:KXK62495.1};
OS Micromonospora rosaria.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Micromonospora.
OX NCBI_TaxID=47874 {ECO:0000313|EMBL:KXK62495.1, ECO:0000313|Proteomes:UP000070620};
RN [1] {ECO:0000313|EMBL:KXK62495.1, ECO:0000313|Proteomes:UP000070620}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 803 {ECO:0000313|EMBL:KXK62495.1,
RC ECO:0000313|Proteomes:UP000070620};
RA Yang H., He X., Zhu D.;
RT "Whole genome sequence and analysis of Micromonospora rosaria DSM 803,
RT which can produce antibacterial substance rosamicin.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXK62495.1}.
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DR EMBL; LRQV01000018; KXK62495.1; -; Genomic_DNA.
DR RefSeq; WP_067362033.1; NZ_LRQV01000018.1.
DR AlphaFoldDB; A0A136PVR8; -.
DR OrthoDB; 3400185at2; -.
DR Proteomes; UP000070620; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-UniRule.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR000212; DNA_helicase_UvrD/REP.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014016; UvrD-like_ATP-bd.
DR InterPro; IPR027785; UvrD-like_helicase_C.
DR PANTHER; PTHR11070:SF45; ATP-DEPENDENT DNA HELICASE UVRD2; 1.
DR PANTHER; PTHR11070; UVRD / RECB / PCRA DNA HELICASE FAMILY MEMBER; 1.
DR Pfam; PF13245; AAA_19; 1.
DR Pfam; PF13538; UvrD_C_2; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51198; UVRD_HELICASE_ATP_BIND; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU00560};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU00560}; Reference proteome {ECO:0000313|Proteomes:UP000070620}.
FT DOMAIN 182..568
FT /note="UvrD-like helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51198"
FT COILED 11..38
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 203..210
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00560"
SQ SEQUENCE 705 AA; 77521 MW; 757EBA0F5C8AA96D CRC64;
MTDHTSLDRE IAVEQRQLDR VYARLAELRR AAARAERDGY RLARVGTFGA LVERDAMVFH
AAQRRHLLDA EHEGLVFGRL DLREGQTLYV GRLGVRDENA ETLVVDWRAP AAEPFYRATP
AAPLGVIRRR TIQSSDERVT RIEDDLLDPS AAPAEMTVVG DGALLASLSK ATGRGMRDIV
ATIQREQDEA IRSPGSGVTI VSGGPGTGKT AVALHRAAYL LYSDRNRYAG GGILVVGPSS
VFVEYVASVL PSLGEESATL RSLGTLFTGL TSTRTDPPDV AAVKGSLRMR RVLERAARDA
VPDGPTELRL LYRGELLRLT RAELDAIRDR ALPRGARRNE VRRAGFDGIF AALWAQARKL
RVGRLPEQRA FEDEIAERPE FREFLKAWWP RLHPRHVLGW LARPERLRGY AGGIFSRAEI
RLLDAAWRTL DTEGLTIADI ALLDELDALL GKPVQPARRT RDPYTLAGGV RELSTHADRQ
RAARAAARQR PEDYREYAHV VVDEAQDVSP MQWRMIGRRG RLASWTVVGD PAQTAWTGDQ
AELSRARDQA LGRRRQHRFT LTTNYRNPAE IFAVAAAEIR RVDPDLPLPT AVRSTGVEPV
RQVVPAAELA AATVAAAEAL LAEVPGTVGV ITPVPRRDEV AGWLGERGGT RLQVVTSLQA
KGMEYDGVVL VAPGEIRADP GSGVRTLYVA LSRATQRLIT LDITG
//
