ID A0A136WGH3_9FIRM Unreviewed; 1128 AA.
AC A0A136WGH3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=ATP-dependent helicase/deoxyribonuclease subunit B {ECO:0000313|EMBL:KXL53540.1};
DE EC=3.1.-.- {ECO:0000313|EMBL:KXL53540.1};
DE EC=3.6.4.12 {ECO:0000313|EMBL:KXL53540.1};
GN Name=addB {ECO:0000313|EMBL:KXL53540.1};
GN ORFNames=CLNEO_07660 {ECO:0000313|EMBL:KXL53540.1};
OS Anaerotignum neopropionicum.
OC Bacteria; Bacillota; Clostridia; Eubacteriales; Lachnospiraceae;
OC Anaerotignum.
OX NCBI_TaxID=36847 {ECO:0000313|EMBL:KXL53540.1, ECO:0000313|Proteomes:UP000070539};
RN [1] {ECO:0000313|EMBL:KXL53540.1, ECO:0000313|Proteomes:UP000070539}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM-3847 {ECO:0000313|EMBL:KXL53540.1,
RC ECO:0000313|Proteomes:UP000070539};
RA Poehlein A., Beck M.H., Bengelsdorf F.R., Daniel R., Duerre P.;
RT "Genome sequence of Clostridium neopropionicum X4, DSM-3847.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXL53540.1}.
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DR EMBL; LRVM01000002; KXL53540.1; -; Genomic_DNA.
DR RefSeq; WP_066084808.1; NZ_LRVM01000002.1.
DR AlphaFoldDB; A0A136WGH3; -.
DR STRING; 36847.CLNEO_07660; -.
DR PATRIC; fig|36847.3.peg.914; -.
DR OrthoDB; 9758506at2; -.
DR Proteomes; UP000070539; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000724; P:double-strand break repair via homologous recombination; IEA:InterPro.
DR Gene3D; 3.90.320.10; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 4.
DR InterPro; IPR049035; ADDB_N.
DR InterPro; IPR014140; DNA_helicase_suAddB.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR011604; PDDEXK-like_dom_sf.
DR InterPro; IPR038726; PDDEXK_AddAB-type.
DR NCBIfam; TIGR02773; addB_Gpos; 1.
DR PANTHER; PTHR30591; RECBCD ENZYME SUBUNIT RECC; 1.
DR PANTHER; PTHR30591:SF1; RECBCD ENZYME SUBUNIT RECC; 1.
DR Pfam; PF21445; ADDB_N; 1.
DR Pfam; PF12705; PDDEXK_1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Helicase {ECO:0000313|EMBL:KXL53540.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KXL53540.1};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000070539}.
FT DOMAIN 5..288
FT /note="ATP-dependent helicase/deoxyribonuclease subunit B
FT N-terminal"
FT /evidence="ECO:0000259|Pfam:PF21445"
FT DOMAIN 759..1102
FT /note="PD-(D/E)XK endonuclease-like"
FT /evidence="ECO:0000259|Pfam:PF12705"
SQ SEQUENCE 1128 AA; 128102 MW; FC08E9D57BB3EFCF CRC64;
MALRFIIGTA GTGKTHLCMD EIIKKQSTGT GRQIFIVPEQ FTSQAERDLI THSPQNAILL
AEVLSFGRLA HGIFSKNGIG QKVPLGDVGK SMALQKVLLD EKENLTFFRN VMNKSGFVDQ
LSLTISEFFQ YYIAPSQLIE KAQAQTLTKG VTQKLTDLAK IYEAYISFTK KDYISADETL
ALLAAQLSTS KLFQDTEIWL DGFYGFTPQE FSVIENLLKL STRVTVTLPM DEKSFTAPFL
LSSAPFYAPY TAKNKLVHLA EESGISVEPP VFLSENHRAQ NEALKSLEKY YFQGYYKKCS
LTQGVQIISC PTKQEEIMFA AGKITSLVRE KGVRYKEIAI VTNAMEVYEK SLRGILREYN
IPCFIDSRRE ISSHPLITMV TALMDCLVYD FRYENVFSYL KSGLTPFSYE ELDALENYVL
AYGIKGYKWQ KEAWEYGRKK EGEEAIREMN CLRQRFMEPF LPFLERKKNA QHPLKEFISM
LIQHLESLGV AETLAMWTEE ATKYGSPAKA EEHRQIWQLL MQVLEKATEI LGDEPMTMAD
AAKILSAGLQ KCTMGVIPPT TDCLVVGDIE RSRLAEIKFL FVLGVNEGIL PSPTQPQGIF
TEAERQLLAE TGMELASGGK QKAFEEQFLI YRGLTRPSKG LFLTYANGET EGKALFPSSI
LDRLCRMDGE LKVQPYSGFR LEEMVPHSAF QLLGEKMREH KKELPMEPLW QDIYSFFATE
PQWEKRLALL RKGFVTTKKQ EKLSPKTLKM LYSEKIFSSV SRLERFAACP FSYFAEYGLK
ATERKLYQLH TPDLGSLFHE VLELFSNKIK TENLAWDTLS QEKTEELIFE AVDLAAPKLG
DQILMDTAAN QYLIRRLKRI SARAAWTLVR HLKSGDFVPA GYEIGFGNHE ALPPIIIQLA
EGNQLVLSGK IDRVDLLDAH GNRYAKIIDY KSGSKAFSFQ DIYYGLQLQL LVYLDAYLKH
YEKTTTPLKP GGVFYFRIMD PNISLSQEMS AEEIEEALYE KMQMSGLILE NDAVIQGLDR
IFIEDVKGKS SAIVPIGYTK KGDPSSSAYL ADETQYEKLL SFVVKQAAEL GNSIQKGIIT
PSPYRKGDQT PCSYCRFKGI CRYDYADEPK WRNLKKIGKK DFWGMIEE
//
