ID A0A137P6E9_CONC2 Unreviewed; 1873 AA.
AC A0A137P6E9;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=SEC7 domain-containing protein {ECO:0000259|PROSITE:PS50190};
GN ORFNames=CONCODRAFT_17574 {ECO:0000313|EMBL:KXN70491.1};
OS Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)
OS (Delacroixia coronata).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Entomophthoromycetes; Entomophthorales;
OC Ancylistaceae; Conidiobolus.
OX NCBI_TaxID=796925 {ECO:0000313|EMBL:KXN70491.1, ECO:0000313|Proteomes:UP000070444};
RN [1] {ECO:0000313|EMBL:KXN70491.1, ECO:0000313|Proteomes:UP000070444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 28638 {ECO:0000313|EMBL:KXN70491.1,
RC ECO:0000313|Proteomes:UP000070444};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
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DR EMBL; KQ964500; KXN70491.1; -; Genomic_DNA.
DR STRING; 796925.A0A137P6E9; -.
DR EnsemblFungi; KXN70491; KXN70491; CONCODRAFT_17574.
DR OMA; XVKNKMT; -.
DR OrthoDB; 204547at2759; -.
DR Proteomes; UP000070444; Unassembled WGS sequence.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProt.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
DR CDD; cd00171; Sec7; 1.
DR Gene3D; 1.10.220.20; -; 1.
DR Gene3D; 1.10.1000.11; Arf Nucleotide-binding Site Opener,domain 2; 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR032629; DCB_dom.
DR InterPro; IPR015403; Mon2/Sec7/BIG1-like_HDS.
DR InterPro; IPR032691; Mon2/Sec7/BIG1-like_HUS.
DR InterPro; IPR046455; Sec7/BIG1-like_C.
DR InterPro; IPR023394; Sec7_C_sf.
DR InterPro; IPR000904; Sec7_dom.
DR InterPro; IPR035999; Sec7_dom_sf.
DR PANTHER; PTHR10663; GUANYL-NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR10663:SF375; LD29171P; 1.
DR Pfam; PF20252; BIG2_C; 1.
DR Pfam; PF16213; DCB; 1.
DR Pfam; PF01369; Sec7; 1.
DR Pfam; PF09324; Sec7-like_HDS; 1.
DR Pfam; PF12783; Sec7-like_HUS; 1.
DR SMART; SM00222; Sec7; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF48425; Sec7 domain; 1.
DR PROSITE; PS50190; SEC7; 1.
PE 4: Predicted;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000070444};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 627..814
FT /note="SEC7"
FT /evidence="ECO:0000259|PROSITE:PS50190"
FT REGION 278..309
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 597..626
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1826..1846
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 278..292
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..309
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1873 AA; 211962 MW; E2E1FF61B676306B CRC64;
MNFEITNQTI EKLQSEAKAK KENELVTLCS KALEDLTQVK SRLVGGKALP PPPSAMEEND
GRDDIIVTDT VSEEFIGDRY YKVFQLGIST KMPIKIQQVT LDALHKLIAH NLLNGNESWE
YNDSLFSNTI LSTRSTMVFD NGLINFDQYF KATEVNDLLE LHRVWPWNSD VPSTSSPVPK
TKKGYKLIDD LVYSVCRCYN GPKTDESIQI QVAQVLITLY ASPCTSIHTV SLLHIIMTLL
NMAIYSTKPS TLNVAKATMI QIVNLAVSRL EECHLRQSSK QSTSSVDVNH SNDEKTPQNE
EVSEAKTSNS LSDEEFTKLE ILKLDVLILL QFLCHFSMGN DKLSSDSQVS TALDARCRSY
SLELILSTLN NSGSCFKSDE RFQTILKRNL CISLSKNGIF AEATIFELSL SIFIVLFSEF
RALLKNEIEL LFKEIYIRLL TMSNSTYYQK SLILQAFMKI CDNSQAIVDM YVNYDCHLGS
SSVFEAMVST LSKISQGRPT KAMQNTQNKG IFNKGDKTEE LDKVEENWLR LRGLRCLVTL
IQSLVGWSQM SQSSELPITP VAQSHSRASS EVIDGASDQL KDQRGPIVVN KHHLQHVSIS
DSSPRQLFSP HLLNRPSSTQ SEDDPQQLLE LSNKKQIWVQ GVEKFNQNPK KGIKFLREQG
FVGETSEEVA SFLLSKDELS KPSIGEFLGD PDQFNINVMH EFVNQIDFEG LEFVNALRKF
LQLFRLPGES QKIDRIMEKF ADRYCETNPN VFNNADAAYV LAFSVIMLNT DQHSNQVRNK
MDKVMFIRNN QGIDNGKNLP QEFLEAIFDD IGENEIIMES ERFDDNSSKG DSKAAYQKEA
SYLQKKLLSL FQGIPLRESD QIFLSATQSD HVKPMFGVAW YSIIAALSRI FEEVNEEDNN
EWSGMKDKNP IPEPIRLCLE GFSGAIRITS IYSMDVERNA FVSAMVKFTS LSDIPSIQVK
HVACIHSLLT LAHAYGEYLE DSWDLILDVV SRLDQLKLLS DPAVVKSRKA SISSISQQSN
ISNESTEQVS IEGQTMSLPA KDIRLSLNLN TDLTHLQQLK VVPDIGPQLK SLSHQNTLVV
IDQIFSKSVQ FGASSILSFY RALCNVSLKE MEELPPANPR SFSLQKIVEI TYYNMDRMRL
EWSQIWKVLR PYFNTVGCHR NFNLASIAVD SLRQLGMKFL ERKELNHFHT QQEFMKPFEH
IVKYSSSSGI HDLVLQSLTQ MVQSKADCLK SGWKSLFTVL NYITKRQPSI SVLSSSWKLC
RYVLTTYIEH IDTSFVDGIN CLVAFVINPV SQDIRVEALQ LFKQISDIQL DGFNQELNSD
GSEFFNEDKL FLKWFPILSG LSKIVIDCPH PQLKSKALNQ LFDTVKQCAD KFSKEFWKAL
LRSIVAPIFD DLRSTPSLSD SSSATTTTWS EAIENLVSLF RDHYDSLHSN LDYTDYMFDT
LASMLLLHRN EKLTKQSLTL FQILVLENGY RFNEDMWRTV TRCLSSFFDQ TTPESLFQLV
PAVSPKTVDL NSHPIAQLTA NELNEQSDIS STAQASEIDL NNAPFSSNSE STHAMLDEDN
EIQSPSAPKT TNNIDVPNEL FKCSVHLTLL QSLKTILVTP RPESDSSESQ QLPLVMLMPR
HISQIWLGLL QKSALFAQKF NEFDELRTHL WRSGYVTHLP HLIRQETSAK GTFIQLGFQV
YGQFGDDYTS SSMGSNDKDD DNVLPTSFFI ELNEECYSIL NKFEGMLREL PTNPSRSRDL
SNWSHLVSLI LTEISNIPWQ SSDDLKVEQL RRCLPQYHTL AVNLINTDIV DVRLGVQKFL
RRFGDKILNV LLQGSMTAKE LGLKSVSKPS TPVANGGRKF DLNDPSSLIS QPPLDIDIPE
SDIPSDINSI SLN
//
