ID A0A137PGB1_CONC2 Unreviewed; 342 AA.
AC A0A137PGB1;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=Glycoside hydrolase family 18 protein {ECO:0000313|EMBL:KXN74015.1};
DE Flags: Fragment;
GN ORFNames=CONCODRAFT_30499 {ECO:0000313|EMBL:KXN74015.1};
OS Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)
OS (Delacroixia coronata).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Entomophthoromycetes; Entomophthorales;
OC Ancylistaceae; Conidiobolus.
OX NCBI_TaxID=796925 {ECO:0000313|EMBL:KXN74015.1, ECO:0000313|Proteomes:UP000070444};
RN [1] {ECO:0000313|EMBL:KXN74015.1, ECO:0000313|Proteomes:UP000070444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 28638 {ECO:0000313|EMBL:KXN74015.1,
RC ECO:0000313|Proteomes:UP000070444};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC Evidence={ECO:0000256|ARBA:ARBA00000822};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC {ECO:0000256|RuleBase:RU004453}.
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DR EMBL; KQ964428; KXN74015.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137PGB1; -.
DR STRING; 796925.A0A137PGB1; -.
DR EnsemblFungi; KXN74015; KXN74015; CONCODRAFT_30499.
DR OMA; HIEIMGY; -.
DR OrthoDB; 3203764at2759; -.
DR Proteomes; UP000070444; Unassembled WGS sequence.
DR GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.10.50.10; -; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR InterPro; IPR011583; Chitinase_II.
DR InterPro; IPR029070; Chitinase_insertion_sf.
DR InterPro; IPR001223; Glyco_hydro18_cat.
DR InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR PANTHER; PTHR11177; CHITINASE; 1.
DR PANTHER; PTHR11177:SF406; GH18 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00704; Glyco_hydro_18; 1.
DR SMART; SM00636; Glyco_18; 1.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR PROSITE; PS01095; GH18_1; 1.
DR PROSITE; PS51910; GH18_2; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326};
KW Reference proteome {ECO:0000313|Proteomes:UP000070444}.
FT DOMAIN 1..342
FT /note="GH18"
FT /evidence="ECO:0000259|PROSITE:PS51910"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KXN74015.1"
FT NON_TER 342
FT /evidence="ECO:0000313|EMBL:KXN74015.1"
SQ SEQUENCE 342 AA; 38114 MW; 7B05CA317EED4857 CRC64;
VGYWTDWTID EYPTSAVPWD LLTHVNYAFA LFTDKDWKPK IDSPQSLKEL VAKSKPTGTK
ILISIGGWTG SGYFSPMVAN AANRATFIKN TVDFVNEYKL DGVDFDWEYP GREGNEGNQV
SPQDTANYLI FLKELKAALP SNILITAAVR VQPFDGPGGN PLKDVSQFAP YFDLINIMAY
DINGPWGSPT GPVGGLDFEK GKGTPFSVRQ STTDWSKAGI PKDKLVVGVP FYGYQLGVST
DMSQSDSQYA TITNPNLPSY AYKELFSNNI LSSPLEANTN NGWIRKFDKI TKTPWLFNKN
NKIFVAYDDP LSLAYKTDYV RCNGYRGAML WALNNDYNSL LL
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