ID A0A137PHI4_CONC2 Unreviewed; 475 AA.
AC A0A137PHI4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE SubName: Full=SecY protein {ECO:0000313|EMBL:KXN74440.1};
GN ORFNames=CONCODRAFT_2449 {ECO:0000313|EMBL:KXN74440.1};
OS Conidiobolus coronatus (strain ATCC 28846 / CBS 209.66 / NRRL 28638)
OS (Delacroixia coronata).
OC Eukaryota; Fungi; Fungi incertae sedis; Zoopagomycota;
OC Entomophthoromycotina; Entomophthoromycetes; Entomophthorales;
OC Ancylistaceae; Conidiobolus.
OX NCBI_TaxID=796925 {ECO:0000313|EMBL:KXN74440.1, ECO:0000313|Proteomes:UP000070444};
RN [1] {ECO:0000313|EMBL:KXN74440.1, ECO:0000313|Proteomes:UP000070444}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NRRL 28638 {ECO:0000313|EMBL:KXN74440.1,
RC ECO:0000313|Proteomes:UP000070444};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the SecY/SEC61-alpha family.
CC {ECO:0000256|ARBA:ARBA00005751, ECO:0000256|RuleBase:RU004349}.
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DR EMBL; KQ964423; KXN74440.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137PHI4; -.
DR STRING; 796925.A0A137PHI4; -.
DR EnsemblFungi; KXN74440; KXN74440; CONCODRAFT_2449.
DR OMA; MMRQMFG; -.
DR OrthoDB; 166798at2759; -.
DR Proteomes; UP000070444; Unassembled WGS sequence.
DR GO; GO:0000324; C:fungal-type vacuole; IEA:EnsemblFungi.
DR GO; GO:0005784; C:Sec61 translocon complex; IEA:EnsemblFungi.
DR GO; GO:1904680; F:peptide transmembrane transporter activity; IEA:EnsemblFungi.
DR GO; GO:0015450; F:protein-transporting ATPase activity; IEA:EnsemblFungi.
DR GO; GO:0005048; F:signal sequence binding; IEA:EnsemblFungi.
DR GO; GO:0070843; P:misfolded protein transport; IEA:EnsemblFungi.
DR GO; GO:0031204; P:post-translational protein targeting to membrane, translocation; IEA:EnsemblFungi.
DR GO; GO:0044743; P:protein transmembrane import into intracellular organelle; IEA:EnsemblFungi.
DR GO; GO:0030970; P:retrograde protein transport, ER to cytosol; IEA:EnsemblFungi.
DR GO; GO:0006616; P:SRP-dependent cotranslational protein targeting to membrane, translocation; IEA:EnsemblFungi.
DR GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IEA:EnsemblFungi.
DR Gene3D; 1.10.3370.10; SecY subunit domain; 1.
DR InterPro; IPR002208; SecY/SEC61-alpha.
DR InterPro; IPR030659; SecY_CS.
DR InterPro; IPR023201; SecY_dom_sf.
DR InterPro; IPR019561; Translocon_Sec61/SecY_plug_dom.
DR NCBIfam; TIGR00967; 3a0501s007; 1.
DR PANTHER; PTHR10906:SF1; DSEC61ALPHA; 1.
DR PANTHER; PTHR10906; SECY/SEC61-ALPHA FAMILY MEMBER; 1.
DR Pfam; PF10559; Plug_translocon; 1.
DR Pfam; PF00344; SecY; 1.
DR PIRSF; PIRSF004557; SecY; 1.
DR SUPFAM; SSF103491; Preprotein translocase SecY subunit; 1.
DR PROSITE; PS00755; SECY_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000070444};
KW Translocation {ECO:0000256|ARBA:ARBA00023010};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 40..74
FT /note="Translocon Sec61/SecY plug"
FT /evidence="ECO:0000259|Pfam:PF10559"
SQ SEQUENCE 475 AA; 52535 MW; A207A19B65A2D134 CRC64;
MTFRALHLMR PFVAFIPEVA SPDRKIPFNQ KILWTAITLF IFLVCSQIPL YGIMSSDSSD
PLYWMRVILA SNRGTLMELG ITPIITSGMI LQMLSGANLL EVDYSVREDR ALFGAAQKLF
AIILTLGQAI VSVVSGTFGP ASNLGLGVCL LLIFQLSMAG LIVILLDELL QKGYGLGSGI
NLFIATNICE NIIWKAFSPN TFNIGKGAQF EGAVIALFHL LFTRKNKFAA LYEAFFRSNL
PNITNLLATA FIFALVIYLQ GFRIEIPVKS ARMRGSRGSF PIKLFYTSNM PIMLQSALTS
NLYMVSQMLY TRFPDNFFVR MFGVWEIKEG THQLFAIQGL AYYLSPPSSI ADVFKDPIHF
VIYVVFMLGA CALFSRTWIE VSGSSPRDVA KQLKDQQTVI AGHRDTSMYK VLKRVIPQAA
TVGGLLIGLL SVVADLMGAI GSGTGILLAV TIIYQYFEMF VREQQEAGGM PGMMQ
//
