ID A0A137QLK3_9AGAR Unreviewed; 583 AA.
AC A0A137QLK3;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DNA polymerase alpha subunit B {ECO:0000256|ARBA:ARBA00018596, ECO:0000256|PIRNR:PIRNR018300};
GN ORFNames=AN958_07577 {ECO:0000313|EMBL:KXN88118.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN88118.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN88118.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN88118.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Accessory subunit of the DNA polymerase alpha complex (also
CC known as the alpha DNA polymerase-primase complex) which plays an
CC essential role in the initiation of DNA synthesis.
CC {ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR018300}.
CC -!- SIMILARITY: Belongs to the DNA polymerase alpha subunit B family.
CC {ECO:0000256|ARBA:ARBA00007299, ECO:0000256|PIRNR:PIRNR018300}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ962167; KXN88118.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137QLK3; -.
DR STRING; 1714833.A0A137QLK3; -.
DR OrthoDB; 49016at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR Gene3D; 3.60.21.60; -; 2.
DR InterPro; IPR007185; DNA_pol_a/d/e_bsu.
DR InterPro; IPR016722; DNA_pol_alpha_bsu.
DR InterPro; IPR013627; Pol_alpha_B_N.
DR PANTHER; PTHR23061; DNA POLYMERASE 2 ALPHA 70 KDA SUBUNIT; 1.
DR PANTHER; PTHR23061:SF12; DNA POLYMERASE ALPHA SUBUNIT B; 1.
DR Pfam; PF04042; DNA_pol_E_B; 1.
DR Pfam; PF08418; Pol_alpha_B_N; 2.
DR PIRSF; PIRSF018300; DNA_pol_alph_2; 2.
PE 3: Inferred from homology;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|PIRNR:PIRNR018300}; Nucleus {ECO:0000256|PIRNR:PIRNR018300};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT DOMAIN 22..87
FT /note="DNA polymerase alpha subunit B N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08418"
FT DOMAIN 149..191
FT /note="DNA polymerase alpha subunit B N-terminal"
FT /evidence="ECO:0000259|Pfam:PF08418"
FT DOMAIN 310..538
FT /note="DNA polymerase alpha/delta/epsilon subunit B"
FT /evidence="ECO:0000259|Pfam:PF04042"
SQ SEQUENCE 583 AA; 64162 MW; 73A52287D1724E71 CRC64;
MVTYTAKDVT NHIGSLIGDD KTVIEECLAI CNNFNISPED LRWKLEAANF KTSATHSEIA
SVTLDTIVVL KAQMQRDLTR ERKVQPKTTV IPNVNRARRN IHLPGMEPAT GAPAVMGKAV
AQVKQEDILV VGQSRVVFSG PSQDEAAKKQ RAYRYMFEKQ IERSEQLDEM IEDAAELIRK
HYKIEEIGDP GTTTDDDIVI VGRIFQDVEV ETSKLTESSV FLESSRMLSG GSRIALKFDS
QLVIRNNIRG ARGLGLFPGA IAAVQGRNGG GGYFLVKEIF TLPVPPRTTS PPVANTMKVD
PVDSNSFSLA IACGPFTADS DLTYVPLANL IETLQKGKPS ALLLIGPFID AAHPSIKIGD
LDVTVVDLFR RRIYKPLKTF LDASPGSIAI LLPGVRDLVI QHAVYPQSEL SPDWTQNDPR
IYLVPNPARF KINDISFGAC SVDVLFHLRR EEFMKAGREV DPVDPVHEDD VGTDAMAGLC
RHLLQQRNFY PIFPSPQELA HEVNLDISHS NSLKLVDEAS SSPPDVLILP SKLKQFVKTV
HATTAVNPSF LSKGTYVLMK VAEGTGTSSV KQRLDCEIAR LEK
//
