ID A0A137QNR5_9AGAR Unreviewed; 699 AA.
AC A0A137QNR5;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Calcium-binding mitochondrial carrier protein {ECO:0000313|EMBL:KXN88836.1};
GN ORFNames=AN958_06705 {ECO:0000313|EMBL:KXN88836.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN88836.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN88836.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN88836.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Homodimer (via N-terminus). {ECO:0000256|ARBA:ARBA00038674}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}. Mitochondrion
CC inner membrane {ECO:0000256|ARBA:ARBA00004448}; Multi-pass membrane
CC protein {ECO:0000256|ARBA:ARBA00004448}.
CC -!- SIMILARITY: Belongs to the mitochondrial carrier (TC 2.A.29) family.
CC {ECO:0000256|ARBA:ARBA00006375}.
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DR EMBL; KQ962127; KXN88836.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137QNR5; -.
DR STRING; 1714833.A0A137QNR5; -.
DR OrthoDB; 1220009at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0043490; P:malate-aspartate shuttle; IEA:UniProt.
DR CDD; cd00051; EFh; 2.
DR Gene3D; 1.10.238.10; EF-hand; 2.
DR Gene3D; 1.50.40.10; Mitochondrial carrier domain; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR002067; Mit_carrier.
DR InterPro; IPR018108; Mitochondrial_sb/sol_carrier.
DR InterPro; IPR023395; Mt_carrier_dom_sf.
DR PANTHER; PTHR45678:SF9; CALCIUM-BINDING MITOCHONDRIAL CARRIER PROTEIN ARALAR1; 1.
DR PANTHER; PTHR45678; MITOCHONDRIAL 2-OXODICARBOXYLATE CARRIER 1-RELATED; 1.
DR Pfam; PF13405; EF-hand_6; 1.
DR Pfam; PF13499; EF-hand_7; 1.
DR Pfam; PF13833; EF-hand_8; 1.
DR Pfam; PF00153; Mito_carr; 3.
DR PRINTS; PR00926; MITOCARRIER.
DR SMART; SM00054; EFh; 2.
DR SUPFAM; SSF47473; EF-hand; 2.
DR SUPFAM; SSF103506; Mitochondrial carrier; 1.
DR PROSITE; PS00018; EF_HAND_1; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
DR PROSITE; PS50920; SOLCAR; 3.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Mitochondrion inner membrane {ECO:0000256|ARBA:ARBA00022792};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|PROSITE-
KW ProRule:PRU00282}; Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 113..148
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT DOMAIN 185..220
FT /note="EF-hand"
FT /evidence="ECO:0000259|PROSITE:PS50222"
FT REPEAT 351..441
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 450..537
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REPEAT 548..636
FT /note="Solcar"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00282"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 699 AA; 77702 MW; AE7B4865181E7DE3 CRC64;
MASDSPVLPT THADAPDGKS SPLSSAFKTV RAAVSVPESE LKRWRRAFEA NAKVVNGGRF
LDSESFVNAI APKGDLTKID KAQFAVLFRV ADTSRRGLVS WEDFTVFETL LKRPDADYWI
AFQFFDVDDS GYITFDEFKT VFSANIGPDA IPFDFDCDWV KLYLGKKDGA HVLGYNEFTQ
LMKGLQGERV RQAFKHLDKD QDGYITPEQF KRIILEIAGH KLSDAVIDRL PTLCTLTPGQ
RISYSEVIAF HNVIREMDMV ERIIREATAK SKDGRIDQSD FLNHSASSSR YSLFTPMEAS
IIFHFAGRGS ANQRLALLDF AQLLDPRWKV PHAEIEAHIP PTKASFLNQV LQSTYSFVQG
GIAGAFGATI VYPIDMVKTR MQNQRSTVVG QLLYKNSIDC ARKIFRNEGF LGFYRGLGPQ
LVGVAPEKAI KLTVNDLIRS RAMDPETGRI KVFWELVAGG MAGGCQVVFT NPLEIVKIRL
QVQGEAAKLE GIKPRGALHI IRQLGILGLY KGATACLLRD IPFSAIYFPV YSHLKTDVFH
EGYNGKKLSF VETLTAAAIA GMPAAYLTTP ADVVKTRLQV EAKKGQTHYK GLRDTFVKIY
HEEGFRALFK GGPARVIRSS PQFGFTLLGY ETLKTLFPYP WQDAPPQVST ALTSRKDELA
QIRARNALKI LLDVHGDFGR RANTSGAPLS LSHPRLSSS
//
