ID A0A137QSP1_9AGAR Unreviewed; 556 AA.
AC A0A137QSP1;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Flap endonuclease 1 {ECO:0000313|EMBL:KXN90295.1};
GN ORFNames=AN958_04328 {ECO:0000313|EMBL:KXN90295.1};
OS Leucoagaricus sp. SymC.cos.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN90295.1, ECO:0000313|Proteomes:UP000070249};
RN [1] {ECO:0000313|EMBL:KXN90295.1, ECO:0000313|Proteomes:UP000070249}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SymC.cos {ECO:0000313|EMBL:KXN90295.1,
RC ECO:0000313|Proteomes:UP000070249};
RA Hu H.;
RT "Leucoagaricus sp. SymC.cos WGS genome.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
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DR EMBL; KQ962050; KXN90295.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A137QSP1; -.
DR STRING; 1714833.A0A137QSP1; -.
DR OrthoDB; 1430882at2759; -.
DR Proteomes; UP000070249; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProt.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 3.40.50.1010; 5'-nuclease; 2.
DR InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR InterPro; IPR008918; HhH2.
DR InterPro; IPR029060; PIN-like_dom_sf.
DR InterPro; IPR006086; XPG-I_dom.
DR InterPro; IPR006084; XPG/Rad2.
DR InterPro; IPR006085; XPG_DNA_repair_N.
DR PANTHER; PTHR11081; FLAP ENDONUCLEASE FAMILY MEMBER; 1.
DR PANTHER; PTHR11081:SF74; XPGN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00867; XPG_I; 1.
DR Pfam; PF00752; XPG_N; 1.
DR PRINTS; PR00853; XPGRADSUPER.
DR SMART; SM00279; HhH2; 1.
DR SMART; SM00484; XPGI; 1.
DR SMART; SM00485; XPGN; 1.
DR SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR SUPFAM; SSF88723; PIN domain-like; 1.
PE 4: Predicted;
KW Endonuclease {ECO:0000313|EMBL:KXN90295.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT DOMAIN 1..100
FT /note="XPG N-terminal"
FT /evidence="ECO:0000259|SMART:SM00485"
FT DOMAIN 352..422
FT /note="XPG-I"
FT /evidence="ECO:0000259|SMART:SM00484"
FT REGION 267..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 556 AA; 61970 MW; 697A63681BBF75FC CRC64;
MGVLGLTPFL QKNYPQIIHK LPNRLKDLAG KRLVIDGTLI TQRLHYAPSP HPFRHVLGWY
HLAREMNENG VSAICIFDGQ KRSKAKAKEV GRRREIKRLD VFRGNLEQLR MKRLEVLKTT
MSSVRSLDDR GRSTIAEMLS RLHPNDGPLV EETPDEILVS REETLVESTH GSQPQVKERP
RQLSCEVSPI PSTPDKIPVV TESAEAPVDS VALEHVSQPQ DSSFLGLQSP PVPGIPVHLP
SAEDLKWTLL SSYRDFRTSI SKIASLPLPK ATTPPAPSPL TSEDEESNTE DDIALTKTQC
ELTLEEDNFV LHAAEDRLDA LKTRSELVSD SYQRRMCVPT RNTYMESKEI LEAMGVLCYE
IEGEYEGEAL ASSLVMKGLA DYVVSEDSDV LVYEAPLIRN ITGRCDPLVL IHGSDVRSVL
ELSRDSYIDF ALLLGTDFSE RIKNVGPSRA HKFIKEYGTI ENVIGSQSKF QPKTSRTDYL
AQVNSARAVF NSLPPLPDRL AVSMLSTEFG VVDTAKVNVI MERCGLGKAL MLDACWDYEA
ALEGNYFDDN PAQILS
//
