ID   A0A137QUR0_9AGAR        Unreviewed;       921 AA.
AC   A0A137QUR0;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   13-SEP-2023, entry version 23.
DE   RecName: Full=Suppressor of hairless protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AN958_03089 {ECO:0000313|EMBL:KXN91022.1};
OS   Leucoagaricus sp. SymC.cos.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX   NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN91022.1, ECO:0000313|Proteomes:UP000070249};
RN   [1] {ECO:0000313|EMBL:KXN91022.1, ECO:0000313|Proteomes:UP000070249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SymC.cos {ECO:0000313|EMBL:KXN91022.1,
RC   ECO:0000313|Proteomes:UP000070249};
RA   Hu H.;
RT   "Leucoagaricus sp. SymC.cos WGS genome.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the Su(H) family.
CC       {ECO:0000256|ARBA:ARBA00009704}.
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DR   EMBL; KQ962020; KXN91022.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A137QUR0; -.
DR   STRING; 1714833.A0A137QUR0; -.
DR   OrthoDB; 1384914at2759; -.
DR   Proteomes; UP000070249; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IEA:InterPro.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR   Gene3D; 2.60.40.1450; LAG1, DNA binding domain; 1.
DR   InterPro; IPR015350; Beta-trefoil_DNA-bd_dom.
DR   InterPro; IPR036358; BTD_sf.
DR   InterPro; IPR040159; CLS_fam.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR008967; p53-like_TF_DNA-bd_sf.
DR   InterPro; IPR015351; RBP-J/Cbf11/Cbf12_DNA-bd.
DR   InterPro; IPR037095; RBP-J/Cbf11_DNA-bd_sf.
DR   InterPro; IPR038007; RBP-Jkappa_IPT.
DR   PANTHER; PTHR10665; RECOMBINING BINDING PROTEIN SUPPRESSOR OF HAIRLESS; 1.
DR   PANTHER; PTHR10665:SF0; SUPPRESSOR OF HAIRLESS PROTEIN; 1.
DR   Pfam; PF09270; BTD; 1.
DR   Pfam; PF09271; LAG1-DNAbind; 1.
DR   Pfam; PF20144; TIG_SUH; 1.
DR   SMART; SM01268; BTD; 1.
DR   SMART; SM01267; LAG1_DNAbind; 1.
DR   SUPFAM; SSF110217; DNA-binding protein LAG-1 (CSL); 1.
DR   SUPFAM; SSF49417; p53-like transcription factors; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070249};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          295..447
FT                   /note="RBP-J/Cbf11/Cbf12 DNA binding"
FT                   /evidence="ECO:0000259|SMART:SM01267"
FT   DOMAIN          448..768
FT                   /note="Beta-trefoil DNA-binding"
FT                   /evidence="ECO:0000259|SMART:SM01268"
FT   REGION          1..59
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          115..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          525..547
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          661..764
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        526..547
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        661..697
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        745..763
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   921 AA;  98833 MW;  59E7001D58CC50FB CRC64;
     MSLDFSAKAS QPQHGLYGQP DLDQSFNIPS SENPDTMETT DHSNYDIFPS SASNGSLSSQ
     AYRTNASSSS SLGHGYGGIN SDNIYSHPFN ASVPSFTGSS DNNPYDIMGA GLPSSYNSSS
     SGKVSPLTPS DSVSGFNPPA DFPPSLGVKD FQPNYPDIER RLPGAGYTQT FDEYGINNMN
     SSIGYPSNGL QQYQERLGRF PAEHRYNHSG PVPPHMPPSV PPHATHGVPP FDGMPHYQAD
     PHQDMALRVP TVDETLARMR LHPIMGQSND LQTFIRPYLD QYVRTANRLA FGERTIIVMS
     SKVAQKSYGT EKRFLCPPPT AIMIGNSWWT DVVRRGEDPK LCPPRVVISI SGEPVPQEGS
     IEWTGSSGKA FDVSDPPTGT TYIGRCVGKQ LFISDVDEKK KKVEALVKVT APASDDEPER
     VIGVFPSRPI KVISKPSKKR QSAKNLELCI NHGSTISLFH RLRSQTVSTK YLCVSGSGSS
     FKGSDGAPLM GLDHRSRSTT PSFIARTASW DPFVMYIVDV NKPAGGIDAP PPPPPQPDYP
     SPPPNAIPFT NNGSQIPIYY NQTVVLQCLT SGVVSPVLII RKVDHQTTVV GGGLQEGAKG
     VPDHYCAPGE VCGDPVSQLH KIAFEVYDSA KTMPEPGTPG ATGAFLSCMG EKVNTYRPID
     GRQWNTTANN GSNSPLPGSP ITSTPKSSGS EYFGHQNVDS APASPAAADF AAHVSNDGGR
     VKKPRSSSSA GGVPKPMAKG RRRPSSAGSV SSRRGSGSDA GASSGALWQV DIGETSVWTI
     VGTDQIRYNF YVPPILFDNQ HAPHTGSFPI PSKPVTPFPG VVKYLPPDRA SEAPKSNCPS
     SRAVLAKPNP HASKMLTVYG ENFSKTEPVS VFFGSDPSPY VEVRCTEVLG CLPPENQVPK
     RRPIVLVRGD GIVFPSSVMY P
//