ID   A0A137QWN8_9AGAR        Unreviewed;       777 AA.
AC   A0A137QWN8;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=AP complex subunit beta {ECO:0000256|PIRNR:PIRNR002291};
GN   ORFNames=AN958_12478 {ECO:0000313|EMBL:KXN91626.1};
OS   Leucoagaricus sp. SymC.cos.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX   NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN91626.1, ECO:0000313|Proteomes:UP000070249};
RN   [1] {ECO:0000313|EMBL:KXN91626.1, ECO:0000313|Proteomes:UP000070249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SymC.cos {ECO:0000313|EMBL:KXN91626.1,
RC   ECO:0000313|Proteomes:UP000070249};
RA   Hu H.;
RT   "Leucoagaricus sp. SymC.cos WGS genome.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Adaptins are components of the adaptor complexes which link
CC       clathrin to receptors in coated vesicles. Clathrin-associated protein
CC       complexes are believed to interact with the cytoplasmic tails of
CC       membrane proteins, leading to their selection and concentration.
CC       {ECO:0000256|PIRNR:PIRNR002291}.
CC   -!- SIMILARITY: Belongs to the adaptor complexes large subunit family.
CC       {ECO:0000256|ARBA:ARBA00006613, ECO:0000256|PIRNR:PIRNR002291}.
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DR   EMBL; KQ961965; KXN91626.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A137QWN8; -.
DR   STRING; 1714833.A0A137QWN8; -.
DR   OrthoDB; 7857at2759; -.
DR   Proteomes; UP000070249; Unassembled WGS sequence.
DR   GO; GO:0030117; C:membrane coat; IEA:InterPro.
DR   GO; GO:0030276; F:clathrin binding; IEA:InterPro.
DR   GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR   GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR026739; AP_beta.
DR   InterPro; IPR016342; AP_complex_bsu_1_2_4.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR002553; Clathrin/coatomer_adapt-like_N.
DR   PANTHER; PTHR11134; ADAPTOR COMPLEX SUBUNIT BETA FAMILY MEMBER; 1.
DR   PANTHER; PTHR11134:SF1; AP-3 COMPLEX SUBUNIT BETA; 1.
DR   Pfam; PF01602; Adaptin_N; 1.
DR   PIRSF; PIRSF002291; AP_complex_beta; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Membrane {ECO:0000256|PIRNR:PIRNR002291};
KW   Protein transport {ECO:0000256|PIRNR:PIRNR002291};
KW   Reference proteome {ECO:0000313|Proteomes:UP000070249};
KW   Transport {ECO:0000256|PIRNR:PIRNR002291}.
FT   DOMAIN          53..582
FT                   /note="Clathrin/coatomer adaptor adaptin-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01602"
FT   REGION          676..777
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        676..712
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        724..748
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        749..777
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   777 AA;  86072 MW;  A0749817595F0CF9 CRC64;
     MSGQQYLNTF TENATRLGMR LQESFSEHTR DLAIGRGVSA AYMDSLDDRG KNIRKQLDSN
     SDREKLDAMK RLIALISKGR NVSEYFAQVV KNVASQNLEI RKLVYIYLLR YAEQEPDLAL
     LSINTFQKDL TDSNPLIRAM ALRVLSGIRV PMIGNIVVLA IKKCAADVSP YVRKTAGLAI
     SRCYELDSGH LSSLIQIITS MLKERSPLAI GSVAVAFDAV CPTRLDLLHP QYRRLCRMLA
     DVDEWGQVDL MNLLLRYART MLPRPTKDEL DPDVKLLLTS VEPVLLSCNP ASVMAAVRVI
     YYAGPPGYLE RVVQPLLKLL HKSREVERVV LVYLLIIVQK ASELFAPHHS RFLLRTDDAL
     EVKRVKIQLL LKILNSENYG TLLREFIDYS DDTDDGIVSD SVLAIGHCAS AIPEATQQCL
     AALITMIQSG NDSVTGPAVM VLKTLVQTQL ASMTSIMGDS PYQAPLSIIA RLARKIDDIK
     NAPARACVIW LVGQYAASEE PCPGPEGIAK WAPDVLRKTA KTFGQEVELV KLQIITLAAK
     LFVLSPEDRT LNLLSQYVFS LARYDNSYDV RDRAKMLRSL LSGISPNISA GLQDERVGVV
     LRREQVRLVL FEGKSGVVED KSSRVEEDAL LGCLSPVLGK PMQMDSLLPD WLEKGVESTL
     RESEDDRLVV PVPTAISSSS IGQRKTMTSP VILTPATTSR PGSRQENIKG TFAQDLDSFY
     ADATSEGESE EGEDSEDDED ENDDSDVKAE DAEDRSEARK NVEDDDSTTE GGYRPRS
//