ID   A0A137R1K6_9AGAR        Unreviewed;      1388 AA.
AC   A0A137R1K6;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=Helicase SEN1 {ECO:0008006|Google:ProtNLM};
DE   Flags: Fragment;
GN   ORFNames=AN958_00334 {ECO:0000313|EMBL:KXN93410.1};
OS   Leucoagaricus sp. SymC.cos.
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Agaricomycetidae; Agaricales; Agaricineae; Agaricaceae; Leucoagaricus.
OX   NCBI_TaxID=1714833 {ECO:0000313|EMBL:KXN93410.1, ECO:0000313|Proteomes:UP000070249};
RN   [1] {ECO:0000313|EMBL:KXN93410.1, ECO:0000313|Proteomes:UP000070249}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SymC.cos {ECO:0000313|EMBL:KXN93410.1,
RC   ECO:0000313|Proteomes:UP000070249};
RA   Hu H.;
RT   "Leucoagaricus sp. SymC.cos WGS genome.";
RL   Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXN93410.1}.
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DR   EMBL; LSHD01033952; KXN93410.1; -; Genomic_DNA.
DR   STRING; 1714833.A0A137R1K6; -.
DR   OrthoDB; 170190at2759; -.
DR   Proteomes; UP000070249; Unassembled WGS sequence.
DR   CDD; cd18808; SF1_C_Upf1; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR045055; DNA2/NAM7-like.
DR   InterPro; IPR041679; DNA2/NAM7-like_C.
DR   InterPro; IPR024481; Helicase_Sen1_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR047187; SF1_C_Upf1.
DR   PANTHER; PTHR10887:SF545; -; 1.
DR   PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR   Pfam; PF13087; AAA_12; 1.
DR   Pfam; PF12726; SEN1_N; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000070249}.
FT   DOMAIN          23..592
FT                   /note="Helicase Sen1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF12726"
FT   DOMAIN          1072..1247
FT                   /note="DNA2/NAM7 helicase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF13087"
FT   REGION          717..804
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1325..1388
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1325..1367
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:KXN93410.1"
SQ   SEQUENCE   1388 AA;  157434 MW;  9F683AF51364D307 CRC64;
     SRDSSGARSI PTPRYQFTTD TFNLWAGFST ALRFIPVEFL KANSRSQVDV RKVVTGHLGD
     TDIHFVEVLR CFNFLLKRLD SSFWVNEPPE YPLMVFDAVK NNTAFAKLIQ STQNNKDEKP
     WHLAWVHEYF RCVQKMEQIY SAVVAKISDF LLEELQHERF GDARPYVLNS ATRLFSSIFS
     RARSEPESLP LKALLSAVDI HANILTRVAL HRDYDKPKWA KARADLRQFL QDILFLDVQQ
     TSAVITETCR LMGHAALKKP LGKIPGLFPR TSLWSKTYQS IHHQDPDGFC TILQLASEAS
     HIDTLNKSTF SPILSLVDVG EAYANGGAVI TAVNTCLTLM RTGFLDGVQN VVDYSTSQLS
     DVLKRPKIGK AVMLLLLSPV DDFHTTAKTL IGQAFDVDGR LECIRTLLET LPDPAIEGLL
     DFLNKFCAYA PSVPEACSLS KSLVRCFTDV IDALCSKPNG LLRNPQFLRC NDSHGPASRM
     MELWMLMSQS IAVIFKRTPS WSIYFDSIEM IEWMRDALIF GRDMLAQWQV VEGAAITFYQ
     QQRKQNPEKS NASLKSLSEI RQKMISCFQD VLTELTRWLR LTDEELLHQS FSLLQSLLGL
     FRKAEIRPCD TALQKLTRYV DSARKDVDQT RSRLDSSRIS SLEDALSIFN DDDDEIQIIS
     EKTTSKAPAI IKKEKKTIDK ATTSRHQLLI TEKSQQDARL GSLDRAEVKS TTSNFFTEKD
     QEKLQKDVAP VPTFKKQEKL APGYRSTLKP KPKEGYKNEA ASSVQPDHSS DSDSDSSESE
     TEAPTGGLTS LAKKFAKSPK IKKPVERRQI KTMEMSSAEK VVMARIHQRE EAHKARMRMR
     PDVSGLHRVL LSWNYDHDDS MPPGFDSKIL RQVPNDFKHH NDFHQVFEPL LLLECWTQIV
     QAKDEIPEVC ECKLSGKQYV DDWLEIDITF ETTLRKDFYL AETDIVLLRQ PQTSKSILAK
     TRGFTTNYQG AQASLRCYLG NGVEDPGLHI GTSWKMSKVF SLSTLHREYA ALKSLPYYDY
     GETILRPKLR RVAPPERSEV QKTMSDFKIN EPQAVAILSG MKTEGFTLIQ GIQYRMHPDI
     SQLPSSVFYQ GRLKDGPRMD EKTIQPWHQN PRFGTYRFFN VHKGLEESSG RSIRNDSECH
     VAVALYNRLK VEYSKVNLDF RVGVVSMYRA QITELKRQFE QRFGKAILGR VDFNTVDGFQ
     GQEKDVIILS CVRSGPGLTQ IGFLSDIRRM NVALTRAKSS LFILGNSATL ERSDNYWAAI
     IDDARSRSCL VDVDHTYFTK PFPAPELNRK LPKTASKVAT KLLPNPPVPD DLFQPQNFKQ
     NQSISLTKPT TSNTPVNGQT DPPQPQVISV KRPAEDSSNS RNTDKQPLQP PVKRPKKAPT
     LFIPKKKT
//