ID A0A137ZZW8_9ACTN Unreviewed; 487 AA.
AC A0A137ZZW8;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=NAD-dependent succinate-semialdehyde dehydrogenase {ECO:0000313|EMBL:KXP03689.1};
GN ORFNames=AXK60_17975 {ECO:0000313|EMBL:KXP03689.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP03689.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP03689.1}.
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DR EMBL; LSRF01000058; KXP03689.1; -; Genomic_DNA.
DR RefSeq; WP_068574718.1; NZ_LSRF01000058.1.
DR AlphaFoldDB; A0A137ZZW8; -.
DR STRING; 239498.AXK60_17975; -.
DR OrthoDB; 6882680at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0016620; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd07103; ALDH_F5_SSADH_GabD; 1.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR016160; Ald_DH_CS_CYS.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR PANTHER; PTHR43353; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43353:SF5; SUCCINATE-SEMIALDEHYDE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345}.
FT DOMAIN 25..483
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 261
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 487 AA; 51036 MW; 910E1085459D8CD2 CRC64;
MATEQRIRDL LDRVPTGIFV NGAFRDSSSG ATFPVHDPAT EEVLIEVADA TAEDGAAALD
AAVAAGPAWA ATPARERAEI LRAAYEGLVA RTDDFALLMT LEMGKALPES ANEVRYGAEF
FRWFSEEAVR IAGRYTPAPA GTGRILVSKA PVGPCLAITP WNFPLAMGTR KLGPALAAGA
TMLVKPAGLT PLTMLLLAEV LKEAGVPDGV VSVLPTSKSS ALTGPLFADP RLRKLTFTGS
TEVGRKLIEQ SAPGVLRTSM ELGGNAPFVV FDDADIDHAV AQALLAKLRN GGEACTAANR
FHVHESVIGE FTDKLVAAME KYVLGPGVQD GVTIGPLISA DQQDIVSELV QDAVAKGATL
RLGGVAPEGP GHFFPPTVLA DVPADARILS EEVFGPVAPI VPFSDEDEAV TAANATEYGL
VSYVFTRDLD RALRVSDRLE SGMVGVNRGV ISDPAGPFGG VKASGFGREG GSEGIEEYLE
TRYIALQ
//
