ID A0A138AUX1_9ACTN Unreviewed; 542 AA.
AC A0A138AUX1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE RecName: Full=Choline dehydrogenase {ECO:0008006|Google:ProtNLM};
GN ORFNames=AXK60_21025 {ECO:0000313|EMBL:KXP14248.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP14248.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP14248.1}.
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DR EMBL; LSRF01000005; KXP14248.1; -; Genomic_DNA.
DR RefSeq; WP_068570068.1; NZ_LSRF01000005.1.
DR AlphaFoldDB; A0A138AUX1; -.
DR STRING; 239498.AXK60_21025; -.
DR OrthoDB; 9785276at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR Gene3D; 3.30.560.10; Glucose Oxidase, domain 3; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR11552:SF147; CHOLINE DEHYDROGENASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR11552; GLUCOSE-METHANOL-CHOLINE GMC OXIDOREDUCTASE; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 1.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827, ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630}.
FT DOMAIN 2..291
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00732"
FT DOMAIN 387..522
FT /note="Glucose-methanol-choline oxidoreductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF05199"
FT BINDING 215
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
SQ SEQUENCE 542 AA; 57868 MW; C6765F57E5CA4208 CRC64;
MYDYIVAGAG SAGCLVANRL SEKHRVLLIE AGGPDDNQWV EIPLGMQRLV GDPEAVWPDR
TKPAEEIAGR SIPLVQGRIM GGSSSVNGMM YVRGQREDYN GWAEAAGDSS WTWDEVLPYF
RKQTAYVDGD PTYFGTDGEL KLTSLTTMHP TTGAYIEAAQ EAGFPLNKNQ NSGDQVGVAV
VMGNIYNGRR QSSAVAFIDP IRDRDSLNVL TNVTVSRVII EDGIAVGVEV IEDGAKREIR
AAKEVVLSAG AIGSATILQL SGIGDAEHLG SLGIPVVADV PGVGKNLQDH LFGHVKFKLR
NDDDSINETL GDAARLAVAL EEWREHGTGA LSSTSSQSLI FFAADPDQTN PDVQLAMRPY
SFGISKEGVL GIDPYPGMMI SSIAARPFSR GVTRIVSTDP TVRPLIDPGY LTDERDIDLL
SAGIAKVRSI AAQPALAGHI DTELEPGPDV ATREQMTDYL RRTVSTVYHP VGTCRMGTGD
DAVVDAQLRV RGVRGLRVID ASIMPTITSG NTNAPTYLIA EKGAAMLLDG QHDPRSAEAA
GA
//
