ID A0A138AV44_9ACTN Unreviewed; 357 AA.
AC A0A138AV44;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Aryl-alcohol dehydrogenase {ECO:0000313|EMBL:KXP14294.1};
GN ORFNames=AXK60_20570 {ECO:0000313|EMBL:KXP14294.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP14294.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947,
CC ECO:0000256|RuleBase:RU361277};
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. {ECO:0000256|RuleBase:RU361277}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP14294.1}.
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DR EMBL; LSRF01000003; KXP14294.1; -; Genomic_DNA.
DR RefSeq; WP_068569985.1; NZ_LSRF01000003.1.
DR AlphaFoldDB; A0A138AV44; -.
DR STRING; 239498.AXK60_20570; -.
DR OrthoDB; 334894at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08278; benzyl_alcohol_DH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR002328; ADH_Zn_CS.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43350; NAD-DEPENDENT ALCOHOL DEHYDROGENASE; 1.
DR PANTHER; PTHR43350:SF19; RIBULOSE-5-PHOSPHATE REDUCTASE; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS00059; ADH_ZINC; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|RuleBase:RU361277};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Zinc {ECO:0000256|RuleBase:RU361277}.
FT DOMAIN 14..349
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 357 AA; 36019 MW; A03BB28E2FB770C9 CRC64;
MNRTVARVVA EPGAAPSDLE VEVPDPTGHQ VLVRIHAVGV CHTDLTLAAN WPEQGMPVIL
GHEGAGVVEA VGPDVTTVRA GDRVSLTFDS CGACEFCAAG TPGYCEQSIV LNYLGLPGIR
SGGTAVTGGF FGQSSFAGLA LATDRNTVPI GDLPLELAAP LGCSIQTGVG TVTRALKVQP
GESVVVFGTG AVGLAAVMGA KLAGAGTIVA VDPRADRRAL ALELGATHAV EAGPQAAQQV
IDATGGGAHA AVDTTARPDA LTQAVLALRP RGTVAVVGLG EASAELPVLL IMSRGLRVIG
VIEGDSEPSE FLPELAAAVA EGRLPVDRLV TAFTDFDEAW AAAREGTAVK PVWLPAG
//
