ID A0A138AWL4_9ACTN Unreviewed; 494 AA.
AC A0A138AWL4;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=MFS transporter {ECO:0000313|EMBL:KXP14833.1};
GN ORFNames=AXK60_02880 {ECO:0000313|EMBL:KXP14833.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP14833.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. Azg-like subfamily. {ECO:0000256|ARBA:ARBA00005697}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP14833.1}.
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DR EMBL; LSRF01000001; KXP14833.1; -; Genomic_DNA.
DR RefSeq; WP_068569445.1; NZ_LSRF01000001.1.
DR AlphaFoldDB; A0A138AWL4; -.
DR STRING; 239498.AXK60_02880; -.
DR OrthoDB; 9808458at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro.
DR GO; GO:1904823; P:purine nucleobase transmembrane transport; IEA:UniProt.
DR InterPro; IPR045018; Azg-like.
DR InterPro; IPR006043; NCS2.
DR PANTHER; PTHR43337; XANTHINE/URACIL PERMEASE C887.17-RELATED; 1.
DR PANTHER; PTHR43337:SF1; XANTHINE_URACIL PERMEASE C887.17-RELATED; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 43..64
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..151
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 163..181
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 201..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 226..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 292..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..391
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..458
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 470..492
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..24
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 494 AA; 50939 MW; 8538E415D587CA5A CRC64;
MTSSQKDAAD ERVEPPTTGS PGTGVLDRFF EITRRGSTVP REIRGGLVTF VAMAYIVVLN
PLILSSSADA AQGTLGFVQV TAVTGLTAGV ITILFGLVAR LPFALAAGLG MNSFLAVAVV
KDVTWPEAMG LVIINGVIIV VLGATGIRTA IFRAVPAELK TAITVGIGLF IAFIGFVNSG
FVTRTPAGPP VQLGHDGSID ALPTAVFIFA LLLIAVLVAR RIPGAILIGM IVATLVAIVV
QHFAKLGTVG DPHHPDPKGW NLSAPELPSH VVALPDFGLI GQFDLVGAFE RIGALSATML
VFTLVFTNFF DAMGSMTGLA RQAGLGQPDG TFPRIRSAFV VEGLGAVAGG ASSGSSNTVF
VDSAAGIAEG ARTGLAACVT GALFLASMFF APVIGVIPME VGAAALVVVG SMMVAQIREI
DFTHFSVALP AFLTIVTMPL TYSIANGIGV GFITWALLSV LSGRGQKAHW LLWAVSVGFI
LYFVRGPITA LIGG
//
