ID A0A138AXJ2_9ACTN Unreviewed; 271 AA.
AC A0A138AXJ2;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=16S/23S rRNA (Cytidine-2'-O)-methyltransferase {ECO:0000313|EMBL:KXP15160.1};
GN ORFNames=AXK60_04740 {ECO:0000313|EMBL:KXP15160.1};
OS Tsukamurella pseudospumae.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Tsukamurellaceae;
OC Tsukamurella.
OX NCBI_TaxID=239498 {ECO:0000313|EMBL:KXP15160.1, ECO:0000313|Proteomes:UP000070258};
RN [1] {ECO:0000313|Proteomes:UP000070258}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JCM 15929 {ECO:0000313|Proteomes:UP000070258};
RA Wen L., He K., Yang H.;
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TlyA family.
CC {ECO:0000256|ARBA:ARBA00029460}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXP15160.1}.
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DR EMBL; LSRF01000001; KXP15160.1; -; Genomic_DNA.
DR RefSeq; WP_068569849.1; NZ_LSRF01000001.1.
DR AlphaFoldDB; A0A138AXJ2; -.
DR STRING; 239498.AXK60_04740; -.
DR OrthoDB; 9784736at2; -.
DR Proteomes; UP000070258; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd00165; S4; 1.
DR Gene3D; 3.10.290.10; RNA-binding S4 domain; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR004538; Hemolysin_A/TlyA.
DR InterPro; IPR002877; RNA_MeTrfase_FtsJ_dom.
DR InterPro; IPR002942; S4_RNA-bd.
DR InterPro; IPR036986; S4_RNA-bd_sf.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR047048; TlyA.
DR NCBIfam; TIGR00478; tly; 1.
DR PANTHER; PTHR32319; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR PANTHER; PTHR32319:SF0; BACTERIAL HEMOLYSIN-LIKE PROTEIN; 1.
DR Pfam; PF01728; FtsJ; 1.
DR Pfam; PF01479; S4; 1.
DR PIRSF; PIRSF005578; TlyA; 1.
DR SMART; SM00363; S4; 1.
DR SUPFAM; SSF55174; Alpha-L RNA-binding motif; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50889; S4; 1.
PE 3: Inferred from homology;
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00182}.
FT DOMAIN 5..69
FT /note="RNA-binding S4"
FT /evidence="ECO:0000259|SMART:SM00363"
SQ SEQUENCE 271 AA; 28747 MW; E54B9C0B364B6C52 CRC64;
MARRVRLDAE LVRRGMARSR EHARELIEAG RVTVNKQVAR KAANQIDPAD PVHVTAVAGE
IEWASRGAHK LLGALAAFPD VPVESRRCLD AGASTGGFTD VLLHRGAERV YAVDVGYGEL
VWRLRDDARV TVLDRTNVRF LEPEQVGGPV DLVVGDLSFI SLGLVLPALA RCTAVGGDLL
PMVKPQFEVG KGNLGTGGVV RDPQLRASAV RGVAEAAAAS GLATRGVAFS PLPGPSGNVE
YFLHLRREEG PVGLPGDVDE MIMTAVTEGP Q
//
