ID A0A139AAN2_GONPJ Unreviewed; 685 AA.
AC A0A139AAN2;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Ras GEF {ECO:0000313|EMBL:KXS13881.1};
GN ORFNames=M427DRAFT_33543 {ECO:0000313|EMBL:KXS13881.1};
OS Gonapodya prolifera (strain JEL478) (Monoblepharis prolifera).
OC Eukaryota; Fungi; Fungi incertae sedis; Chytridiomycota;
OC Chytridiomycota incertae sedis; Monoblepharidomycetes; Monoblepharidales;
OC Gonapodyaceae; Gonapodya.
OX NCBI_TaxID=1344416 {ECO:0000313|EMBL:KXS13881.1, ECO:0000313|Proteomes:UP000070544};
RN [1] {ECO:0000313|EMBL:KXS13881.1, ECO:0000313|Proteomes:UP000070544}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JEL478 {ECO:0000313|EMBL:KXS13881.1,
RC ECO:0000313|Proteomes:UP000070544};
RX PubMed=25977457; DOI=10.1093/gbe/evv090;
RA Chang Y., Wang S., Sekimoto S., Aerts A.L., Choi C., Clum A., LaButti K.M.,
RA Lindquist E.A., Yee Ngan C., Ohm R.A., Salamov A.A., Grigoriev I.V.,
RA Spatafora J.W., Berbee M.L.;
RT "Phylogenomic Analyses Indicate that Early Fungi Evolved Digesting Cell
RT Walls of Algal Ancestors of Land Plants.";
RL Genome Biol. Evol. 7:1590-1601(2015).
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DR EMBL; KQ965773; KXS13881.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139AAN2; -.
DR STRING; 1344416.A0A139AAN2; -.
DR OrthoDB; 68574at2759; -.
DR Proteomes; UP000070544; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR SMART; SM00147; RasGEF; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
PE 4: Predicted;
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000070544}.
FT DOMAIN 452..685
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 128..156
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 168..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 168..206
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 685 AA; 77354 MW; A9EA60B5028B4E9C CRC64;
MQNVPSSHPE LGSSHSREAL KAYGDYRLPK SKVSLKKFRG LMKSVKDIAP RFGISQTMED
VADSLASSWG NAFKPIDQGR SSPRSHNVNV NKPLPLTPLP NIMTSSHFSL AFIDRVFQEA
EQADLLQGAR PDMDDSRDSG DSENPGAFPH FTGSSNALID GALTSSPIEE SDESMVTSTA
HSAASLEVES PGHSQELSSS SESEFPSFAR PRKLTTANHP LRRNQYRQAR RISDVAHVRE
CDATDEADHR DAVIQVEIQP NEQDIEGSSM YVRVARTTEL DAILSSICEA RSMPNEEYTF
VIPGIPVAEL DRNIQYVLER CGGTTFIVTK GTRSYSTRIV CEEGEDVMIV REEGEHEVVM
AGTVPKLVEQ ITPEDEDKTD PPLLRLVGEF LDALQEYRGS PHLPLDFTEE CTRLRAIMEE
QIKLYTKHEL NRSLDHKVKV LPGLREFFLG ISPEDLAKQL CLFNHRLFRN VNPTEYLDFI
WKLNVPEDSP TGMSPILSVF VERFNRESLW VATVICSVAE ERTRRRMLKK FVWTAKCCAE
LNNFFSAFAI LGGLNHAAVR RLKRTRDIGD KYVQAVAELD MLCDPSRNMK RYRERLAACT
PPAIPFIALF FKDLTFLNDG NKSHVDSMVN FDKLRMMAAW VNEVRRFAES EYSYDEVVEV
RNYIACLPVV DDPKKLMQMS SALER
//
