ID   A0A139CI79_9EURY        Unreviewed;       256 AA.
AC   A0A139CI79;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   24-JAN-2024, entry version 19.
DE   SubName: Full=Thymidylate synthase {ECO:0000313|EMBL:KXS40910.1};
GN   ORFNames=AWU59_2333 {ECO:0000313|EMBL:KXS40910.1};
OS   Methanolobus sp. T82-4.
OC   Archaea; Euryarchaeota; Stenosarchaea group; Methanomicrobia;
OC   Methanosarcinales; Methanosarcinaceae; Methanolobus.
OX   NCBI_TaxID=1794908 {ECO:0000313|EMBL:KXS40910.1, ECO:0000313|Proteomes:UP000074030};
RN   [1] {ECO:0000313|EMBL:KXS40910.1, ECO:0000313|Proteomes:UP000074030}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T82-4 {ECO:0000313|EMBL:KXS40910.1};
RA   Wolfe R., Daly R., Wrighton K.;
RT   "Methanolobus T82 Annotated.";
RL   Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KXS40910.1}.
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DR   EMBL; LSRV01000100; KXS40910.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A139CI79; -.
DR   STRING; 1794908.AWU59_2333; -.
DR   Proteomes; UP000074030; Unassembled WGS sequence.
DR   GO; GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.572.10; Thymidylate synthase/dCMP hydroxymethylase domain; 1.
DR   InterPro; IPR023451; Thymidate_synth/dCMP_Mease_dom.
DR   InterPro; IPR036926; Thymidate_synth/dCMP_Mease_sf.
DR   Pfam; PF00303; Thymidylat_synt; 1.
DR   SUPFAM; SSF55831; Thymidylate synthase/dCMP hydroxymethylase; 1.
PE   4: Predicted;
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          78..230
FT                   /note="Thymidylate synthase/dCMP hydroxymethylase"
FT                   /evidence="ECO:0000259|Pfam:PF00303"
SQ   SEQUENCE   256 AA;  29932 MW;  068943DE8689F213 CRC64;
     MEMEAVLIKA KNISSAWSQL IYEIYKKGEE HKPDYNTMTK RVHATIQIED VNTNQVNPAV
     PFGENLIKKY KEELTEEYAD WYISLPEDDK RKFDYCYAKQ LFRYGETAYN NLKENVVNLR
     PGSRRHVGVL WENEVHIPKF EDQPCWIAYK IELINDTQTR VYILYRSWDA FGGFPANIPA
     IVEGIKKVFR EQDLPYEIES LIATGWDTHI YDADLQAVEK IFKSNELCPL CKCIMPKHSF
     IPTTKGRACP ECKKSM
//