ID A0A139GUR4_9PEZI Unreviewed; 663 AA.
AC A0A139GUR4;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 13-SEP-2023, entry version 26.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AC578_7079 {ECO:0000313|EMBL:KXS93935.1};
OS Pseudocercospora eumusae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=321146 {ECO:0000313|EMBL:KXS93935.1, ECO:0000313|Proteomes:UP000070133};
RN [1] {ECO:0000313|EMBL:KXS93935.1, ECO:0000313|Proteomes:UP000070133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114824 {ECO:0000313|EMBL:KXS93935.1,
RC ECO:0000313|Proteomes:UP000070133};
RA Chang T.-C., Salvucci A., Crous P.W., Stergiopoulos I.;
RT "Comparative genomics of the Sigatoka disease complex on banana suggests a
RT link between parallel evolutionary changes in Pseudocercospora fijiensis
RT and Pseudocercospora eumusae and increased virulence on the banana host.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Component of the ESCRT-0 complex composed of HSE1 and VPS27.
CC {ECO:0000256|ARBA:ARBA00011446}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXS93935.1}.
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DR EMBL; LFZN01000358; KXS93935.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139GUR4; -.
DR STRING; 321146.A0A139GUR4; -.
DR OrthoDB; 460229at2759; -.
DR Proteomes; UP000070133; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0016482; P:cytosolic transport; IEA:UniProt.
DR GO; GO:0016197; P:endosomal transport; IEA:UniProt.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProt.
DR CDD; cd14235; GAT_GGA_fungi; 1.
DR CDD; cd16998; VHS_GGA_fungi; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR Gene3D; 2.60.40.1230; -; 1.
DR InterPro; IPR008152; Clathrin_a/b/g-adaptin_app_Ig.
DR InterPro; IPR013041; Clathrin_app_Ig-like_sf.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR008153; GAE_dom.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR47180; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR PANTHER; PTHR47180:SF1; ADP-RIBOSYLATION FACTOR-BINDING PROTEIN GGA1-RELATED; 1.
DR Pfam; PF02883; Alpha_adaptinC2; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00809; Alpha_adaptinC2; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF49348; Clathrin adaptor appendage domain; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50180; GAE; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 4: Predicted;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000070133};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 32..168
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 195..322
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT DOMAIN 545..661
FT /note="GAE"
FT /evidence="ECO:0000259|PROSITE:PS50180"
FT REGION 365..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 456..554
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 456..477
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 663 AA; 71605 MW; 0C47D677BDA72515 CRC64;
MEAASARYAA RDRFAYPAEP AATPLQRYIQ QACSPENFEP NLALCLEVAD LINAKKAGAP
REAAITIVQY INHRNPNVSL LALSLLDICV KNCGYPFHLQ ISTKEFLNEL VRRFPERPPI
RTTRVQNRIL ELIEEWRRTI CETSKYKEDL GFIRDMHRLL HYKGYQFPQI SREDAAVLNP
SDNLKSAEEM EAEERAAQSA KLQELIRRGT PHDLQEANKL MKVMAGYDTR HKTDYRAKAA
EEVGRIQQKA KLLEEMMSEY KPGDKIKDGD VFEELAAALA SAHPKIQKMC EEESEDHEAV
SKLFEINDSI HRTIERYKLM KKGDIEAANA IPKGTLGVSG AGVKQGANNE LSLIDFGGPE
EAGAQHLTAD ATSSSSAPAA PKPAGNALED DLLGLNMGDG NYGQGGGISL GTSDIMAQFN
QPAANSIFNT QPRAAPPAAS QAAPANYSNL FAAGSQPASK AATPNPSSLQ QATHQVKKSD
PFAALNTPPR QGSPASFQQA PPRSPAPPTS SAPVDLLGIG NGTSAPAPAP TAGGDDEWEF
SSALPDGPTS ITVTNSGIHT VFDVSRANDS ELLIKSRISN ASHQPVSDLT FQLAVTKGYT
LKLEPQSGRS LGPKQQNGVT QTIHLQGVER GKGTTVKMRW RASYSVGGAQ QNEQGEINGL
CVP
//
