ID A0A139HGF7_9PEZI Unreviewed; 1737 AA.
AC A0A139HGF7;
DT 06-JUL-2016, integrated into UniProtKB/TrEMBL.
DT 06-JUL-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=FH2 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=AC578_6327 {ECO:0000313|EMBL:KXT01564.1};
OS Pseudocercospora eumusae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Dothideomycetidae; Mycosphaerellales; Mycosphaerellaceae; Pseudocercospora.
OX NCBI_TaxID=321146 {ECO:0000313|EMBL:KXT01564.1, ECO:0000313|Proteomes:UP000070133};
RN [1] {ECO:0000313|EMBL:KXT01564.1, ECO:0000313|Proteomes:UP000070133}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS 114824 {ECO:0000313|EMBL:KXT01564.1,
RC ECO:0000313|Proteomes:UP000070133};
RA Chang T.-C., Salvucci A., Crous P.W., Stergiopoulos I.;
RT "Comparative genomics of the Sigatoka disease complex on banana suggests a
RT link between parallel evolutionary changes in Pseudocercospora fijiensis
RT and Pseudocercospora eumusae and increased virulence on the banana host.";
RL Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the formin homology family. BNI1 subfamily.
CC {ECO:0000256|ARBA:ARBA00037935}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXT01564.1}.
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DR EMBL; LFZN01000053; KXT01564.1; -; Genomic_DNA.
DR STRING; 321146.A0A139HGF7; -.
DR OrthoDB; 1118745at2759; -.
DR Proteomes; UP000070133; Unassembled WGS sequence.
DR GO; GO:0015629; C:actin cytoskeleton; IEA:UniProt.
DR GO; GO:0005938; C:cell cortex; IEA:UniProt.
DR GO; GO:0032153; C:cell division site; IEA:UniProt.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0030036; P:actin cytoskeleton organization; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProt.
DR Gene3D; 6.10.30.50; -; 1.
DR Gene3D; 1.20.58.2220; Formin, FH2 domain; 1.
DR Gene3D; 1.10.238.150; Formin, FH3 diaphanous domain; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR014767; DAD_dom.
DR InterPro; IPR015425; FH2_Formin.
DR InterPro; IPR042201; FH2_Formin_sf.
DR InterPro; IPR010472; FH3_dom.
DR InterPro; IPR014768; GBD/FH3_dom.
DR InterPro; IPR010473; GTPase-bd.
DR PANTHER; PTHR47102; PROTEIN BNI1; 1.
DR PANTHER; PTHR47102:SF2; PROTEIN BNI1; 1.
DR Pfam; PF06367; Drf_FH3; 1.
DR Pfam; PF06371; Drf_GBD; 1.
DR Pfam; PF02181; FH2; 1.
DR SMART; SM01139; Drf_FH3; 1.
DR SMART; SM01140; Drf_GBD; 1.
DR SMART; SM00498; FH2; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF101447; Formin homology 2 domain (FH2 domain); 1.
DR PROSITE; PS51231; DAD; 1.
DR PROSITE; PS51444; FH2; 1.
DR PROSITE; PS51232; GBD_FH3; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000070133}.
FT DOMAIN 236..665
FT /note="GBD/FH3"
FT /evidence="ECO:0000259|PROSITE:PS51232"
FT DOMAIN 1090..1512
FT /note="FH2"
FT /evidence="ECO:0000259|PROSITE:PS51444"
FT DOMAIN 1529..1561
FT /note="DAD"
FT /evidence="ECO:0000259|PROSITE:PS51231"
FT REGION 1..61
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 95..208
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 934..1093
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1505..1533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1545..1737
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 689..716
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..18
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..61
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 145..208
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 953..969
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 979..1069
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1512..1529
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1578..1604
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1635..1664
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1679..1706
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1737 AA; 193220 MW; A4504249B960BF4B CRC64;
MFSSSDKSAR QSSGGKSFFS RNKKDKGSEH GPSHGHAQAT SHESTARHSH SHRSSTSTID
QEEYMKNGHD PLAMQAGVIT SIPYDAMAKD TRPPVLVDSA DRPASKREPL PHHLNKGGGD
FHQYPAFDAS SLPPRPPTHG SSYRGRLDSD ATTLNAYPAS RSSSDHGSIR SNWSGDRRQY
YNGNTSQASL GVGMTGYAPE QSSASQRDRN NQYLNAHNPS AFSSAASFSP EGLLQHRPAD
DKVIEKEFLE LMLKRGWKSL PEQARRQMEA YPISKKWTLV YQDRLAEWQG EQKRRNMARN
TMQSVHGAFD IGRMEEEGSP EWYVKKILDN SITAKQLQSL AVSLRTQPIA WVKAFVEAQG
QIALTNLLGK LNRRQASGPV SVEGSKQEKD LDREYDIVKC LKALMNNKYG ADNALQHDSI
VMALASSLTT PRLHTRKLVS ELLTFLCHWA DGQGHVKVLQ AMDHLKAQQS ENGRFDAWLR
IVEVTIDGRG KMGSLVGASD EVRSGGVGME NLLMEYAVAS LFLVNSIVDA PERDLQLRCH
IRAQFVACGL KRIFTKMEDF QYEVIDKQIE RYRNNEAIDY EDLLERENSS MHESMEGEGR
DLNDPVQIVE AIQQRVAGSR EGDYFLSALQ HLLLIRDNEG EDRVKLFQLV ENMLSYVAMD
RRLPDMDLKQ SLNFSVQSLL DKLYTDSEAR QAREAANEAK LVADAAIAER DEMKSQVEMG
AEGLVAKLQK QIDEQAAVID LQSRQTEAMK SELGELQRVR AQDLQRQELE TRELYLMLRD
AQNIAESNSK KGGKNGETTD PARLQGILDR ERLMDRLEMQ LERAKTQAKL EGKVWQQFNP
SDKLRELREK MEGAGMEPDG LEAQMSYLGQ TAPRRGTGIA RKPVRKAADG DNVDDTIMED
DAVFEKPRLV EYTRPKVPSS VANAQRGMLA ELQSRAPRVD GSDDEGDGVT TGPSHPSLES
ESPKTPTSTD LPEPAKEKFD GPAAPPPPPM PEFDGAAPPP PPPPPGFSND APPPPPPPMP
GFGSSAPPPP PMPGFNGAAP PPPPPPPEMG FKGGAPPPPP PPPGAPPLPG KLHGGFLPKQ
MHTSPNGGIG AVAPRPKKKL KALHWEKVDS PEVTLWSLHT PTFEQKEEKY QELSRKGILD
EIEKLFMAKE IKQIGKGGAK VKTDKKQVIS RDLMHMMQIS LAKFSNVEAD DIVRMVIHCD
REILENSTVM DFLQHEHLCT IPDNVAKLMA PYSKDWTGPD AIKSTREQDP SELTREDQIY
LYTAYELHHY WKARMRALAL TKNFEPEYDE ISGKLKQVVQ VSESLRDSVK LMPVFGLILD
IGNYMNDSNK QAVGFKLSSL ARLGMVKDKD NESTLLDYVE RVVRKQYPQY EGFYEDISGV
LTTQKINIEQ LQGDAKKYID NINNVQSSLD SGNLSDPKRF HPEDRVSQVV QRSMKEARRK
AEQMALYLDE MNRVYDDILT YFGDDNKDEN ARREFFSKLA NFLQEYKKSH EKNLVLEEAW
RRNEENMRRK QMKSGQGSSS ASVSDAPASP VSTGAMDDLL QKLRAAAPVA KDTRERRRRA
RLKDRHQVRV ASGQKIPETG ENMVTDESGL LSPAKTNDSA DSNEPVEGGV SEGEDIADRA
ASMLQGLRGD AEPAESGSES IRVRRRRESA DDERARRRAR RRAAGGSTDT TAATITEEGD
EAAVDKPGEA RIVEEDEEKS GGSDGKRDSG ESPLPTPTTV VVPPSPTASE HSPEKAE
//
