ID A0A139JQV1_9MOLU Unreviewed; 454 AA.
AC A0A139JQV1;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Replicative DNA helicase {ECO:0000256|ARBA:ARBA00021957, ECO:0000256|RuleBase:RU362085};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551, ECO:0000256|RuleBase:RU362085};
GN ORFNames=AXA84_0259 {ECO:0000313|EMBL:KXT29230.1}, DH96_02040
GN {ECO:0000313|EMBL:RAM57703.1};
OS Candidatus Phytoplasma oryzae.
OC Bacteria; Mycoplasmatota; Mollicutes; Acholeplasmatales;
OC Acholeplasmataceae; Phytoplasma; 16SrXI (Rice yellow dwarf group).
OX NCBI_TaxID=203274 {ECO:0000313|EMBL:KXT29230.1, ECO:0000313|Proteomes:UP000070069};
RN [1] {ECO:0000313|EMBL:RAM57703.1, ECO:0000313|Proteomes:UP000249343}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NGS-S10 {ECO:0000313|EMBL:RAM57703.1,
RC ECO:0000313|Proteomes:UP000249343};
RA Kawicha P., Dickinson M., Hodgetts J.;
RT "Genome study of Napier grass stunt phytoplasma.";
RL Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:KXT29230.1, ECO:0000313|Proteomes:UP000070069}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Mbita1 {ECO:0000313|EMBL:KXT29230.1};
RA Fischer A., Santa-Cruz I., Wambua L., Olds C., Midega C., Dickinson M.,
RA Kawicha P., Khan Z., Masiga D., Jores J., Bernd S.;
RT "A draft genome sequence of Candidatus Phytoplasma oryzae strain Mbita1,
RT the causative agent of Napier Grass stunt disease in Kenya.";
RL Submitted (FEB-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in initiation and elongation during chromosome
CC replication; it exhibits DNA-dependent ATPase activity.
CC {ECO:0000256|RuleBase:RU362085}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665,
CC ECO:0000256|RuleBase:RU362085};
CC -!- SIMILARITY: Belongs to the helicase family. DnaB subfamily.
CC {ECO:0000256|ARBA:ARBA00008428, ECO:0000256|RuleBase:RU362085}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXT29230.1}.
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DR EMBL; LTBM01000006; KXT29230.1; -; Genomic_DNA.
DR EMBL; JHUK01000004; RAM57703.1; -; Genomic_DNA.
DR RefSeq; WP_066540351.1; NZ_LTBM01000006.1.
DR AlphaFoldDB; A0A139JQV1; -.
DR PATRIC; fig|203274.3.peg.414; -.
DR OrthoDB; 9773982at2; -.
DR Proteomes; UP000070069; Unassembled WGS sequence.
DR Proteomes; UP000249343; Unassembled WGS sequence.
DR GO; GO:1990077; C:primosome complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0003678; F:DNA helicase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0006269; P:DNA replication, synthesis of RNA primer; IEA:UniProtKB-UniRule.
DR CDD; cd00984; DnaB_C; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007692; DNA_helicase_DnaB.
DR InterPro; IPR007694; DNA_helicase_DnaB-like_C.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR NCBIfam; TIGR00665; DnaB; 1.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF03796; DnaB_C; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51199; SF4_HELICASE; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|RuleBase:RU362085};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705,
KW ECO:0000256|RuleBase:RU362085};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU362085};
KW Helicase {ECO:0000256|RuleBase:RU362085, ECO:0000313|EMBL:KXT29230.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU362085};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741,
KW ECO:0000256|RuleBase:RU362085}; Primosome {ECO:0000256|RuleBase:RU362085};
KW Reference proteome {ECO:0000313|Proteomes:UP000249343}.
FT DOMAIN 183..454
FT /note="SF4 helicase"
FT /evidence="ECO:0000259|PROSITE:PS51199"
SQ SEQUENCE 454 AA; 53496 MW; 60E10FE51F4D4758 CRC64;
MLKNKNQLNY FKNLPLPYYL DAEQAVLGIL FFDEKQIVHV LNQLKNEDFF HPDHQKIYQA
MYHLHQNHKI IDYFSVDLWL KKQCITITGG TDYLMKLGSS FPSLYHLDNY IEFLKEATIK
RKMLQLMNRM VHETLNYENE GHFHQLMEES QAEIKALINS PQKAFLTAKT LFQQIQQQMQ
KRKKESFLGW FTGFAALDEM TGGWQPEQLV ILAARPGMGK TTFMLNLMLK AFANNEHLKV
AVFSLEMNSI QLGLRCLSMM THIPFRQLQT YSFQAFSTQE QKLIETKTEE INYYQLFLDD
EGLNTMTHIK EKCRWLKQTK GLNLVFIDYL QLLKAFESDK ALKSYETVSQ ISRELKLLAK
ELKMTIICLS QLSREIEKRE KKRPQLSDLR DSGSIEQDAD IVIFLARFQP ENIDFHREIV
ETEVIIAKNR NGQIGQCPFL FHLKIQKFEE KKLY
//
