ID A0A139NEH6_9STRE Unreviewed; 504 AA.
AC A0A139NEH6;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zn-dependent hydrolase, RNA-metabolising {ECO:0000313|EMBL:KXT74171.1};
GN ORFNames=STRDD10_01155 {ECO:0000313|EMBL:KXT74171.1};
OS Streptococcus sp. DD10.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1777878 {ECO:0000313|EMBL:KXT74171.1, ECO:0000313|Proteomes:UP000072050};
RN [1] {ECO:0000313|EMBL:KXT74171.1, ECO:0000313|Proteomes:UP000072050}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DD10 {ECO:0000313|EMBL:KXT74171.1,
RC ECO:0000313|Proteomes:UP000072050};
RA Denapaite D., Rieger M., Koendgen S., Brueckner R., Ochigava I.,
RA Kappeler P., Maetz-Rensing K., Leendertz F., Hakenbeck R.;
RT "Highly variable Streptococcus oralis are common among viridans
RT streptococci isolated from primates.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXT74171.1}.
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DR EMBL; LQRE01000091; KXT74171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A139NEH6; -.
DR STRING; 1777878.STRDD10_01155; -.
DR PATRIC; fig|1777878.3.peg.1269; -.
DR Proteomes; UP000072050; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR CDD; cd07714; RNaseJ_MBL-fold; 1.
DR Gene3D; 3.10.20.580; -; 1.
DR Gene3D; 3.40.50.10710; Metallo-hydrolase/oxidoreductase; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR InterPro; IPR011108; RMMBL.
DR InterPro; IPR004613; RNase_J.
DR InterPro; IPR042173; RNase_J_2.
DR InterPro; IPR041636; RNase_J_C.
DR NCBIfam; TIGR00649; MG423; 1.
DR PANTHER; PTHR43694; RIBONUCLEASE J; 1.
DR PANTHER; PTHR43694:SF4; RIBONUCLEASE J 2; 1.
DR Pfam; PF12706; Lactamase_B_2; 1.
DR Pfam; PF07521; RMMBL; 1.
DR Pfam; PF17770; RNase_J_C; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Endonuclease {ECO:0000256|ARBA:ARBA00022759};
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KXT74171.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nuclease {ECO:0000256|ARBA:ARBA00022722};
KW Reference proteome {ECO:0000313|Proteomes:UP000072050};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 16..217
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 504 AA; 55708 MW; 316BF178A42AF29C CRC64;
MTSIKLFSLG GIRENGKNLY VAEINDSIFV LDTGLKYPEN EQLGVDVVIP NMDYLIENRD
RIAGIFLTHG HADAIGALPY LIAGAKKTPV FGSELTIELA KLFVKNNDVV KKFNDFHVID
HNTEIEFGDA IVSFFKTTHS IPESLGIVLK TSEGSIVYTG DFKFDQAATE SYATDFGRLA
EIGREGVLAL LSDSANADSN IQVASESEVA DEILNTIGDC EGRVIVAAVA SNLSRIQQVF
DAAAATGRRV VLTGYDIENI VRTAIRLKKL SLVDERLLIK PKDMNKYEDH ELIILETGRM
GEPINGLRKM SIGRHRYVEI KEGDLIYIVT TPSIAKEAVV ARVENMIYQA GGTVKLITQN
LRVSGHGNAR DLQLMINLIK PKFLFPIQGE YRELDAHAKA AMEVGLLPEK IFIPKRGDIM
VYEKGDFVHS GSIPAGDVMI DGNAMGDVGH IVLRDRKVLS EDGIFIVAIT VNRKKKKLFR
RQKSILVVLS MSRKVGIFYE KVQS
//
