ID A0A139NPV3_9STRE Unreviewed; 1543 AA.
AC A0A139NPV3;
DT 08-JUN-2016, integrated into UniProtKB/TrEMBL.
DT 08-JUN-2016, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Cell wall-associated murein hydrolase LytC {ECO:0000313|EMBL:KXT77893.1};
GN ORFNames=STRDD13_01156 {ECO:0000313|EMBL:KXT77893.1};
OS Streptococcus sp. DD13.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1777881 {ECO:0000313|EMBL:KXT77893.1, ECO:0000313|Proteomes:UP000070387};
RN [1] {ECO:0000313|EMBL:KXT77893.1, ECO:0000313|Proteomes:UP000070387}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DD13 {ECO:0000313|EMBL:KXT77893.1,
RC ECO:0000313|Proteomes:UP000070387};
RA Denapaite D., Rieger M., Koendgen S., Brueckner R., Ochigava I.,
RA Kappeler P., Maetz-Rensing K., Leendertz F., Hakenbeck R.;
RT "Highly variable Streptococcus oralis are common among viridans
RT streptococci isolated from primates.";
RL Submitted (JAN-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytosol
CC {ECO:0000256|ARBA:ARBA00004514}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KXT77893.1}.
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DR EMBL; LQRH01000046; KXT77893.1; -; Genomic_DNA.
DR RefSeq; WP_067102860.1; NZ_KQ969506.1.
DR STRING; 1777881.STRDD13_01156; -.
DR PATRIC; fig|1777881.3.peg.1225; -.
DR OrthoDB; 1089471at2; -.
DR Proteomes; UP000070387; Unassembled WGS sequence.
DR GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR GO; GO:0033925; F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; IEA:UniProtKB-EC.
DR GO; GO:0008152; P:metabolic process; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.3630; -; 2.
DR Gene3D; 1.20.120.1850; Ebh helix bundles repeating unit (S and A modules); 1.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 2.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR032979; ENGase.
DR InterPro; IPR005201; Glyco_hydro_85.
DR InterPro; IPR022038; Ig-like_bact.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR019931; LPXTG_anchor.
DR InterPro; IPR005877; YSIRK_signal_dom.
DR NCBIfam; TIGR01167; LPXTG_anchor; 1.
DR NCBIfam; TIGR01168; YSIRK_signal; 1.
DR PANTHER; PTHR13246:SF1; CYTOSOLIC ENDO-BETA-N-ACETYLGLUCOSAMINIDASE; 1.
DR PANTHER; PTHR13246; ENDO BETA N-ACETYLGLUCOSAMINIDASE; 1.
DR Pfam; PF07523; Big_3; 2.
DR Pfam; PF07554; FIVAR; 2.
DR Pfam; PF03644; Glyco_hydro_85; 1.
DR Pfam; PF00746; Gram_pos_anchor; 1.
DR Pfam; PF04650; YSIRK_signal; 1.
DR PROSITE; PS50847; GRAM_POS_ANCHORING; 1.
PE 4: Predicted;
KW Cell wall {ECO:0000256|ARBA:ARBA00022512};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:KXT77893.1};
KW Peptidoglycan-anchor {ECO:0000256|ARBA:ARBA00023088};
KW Reference proteome {ECO:0000313|Proteomes:UP000070387};
KW Secreted {ECO:0000256|ARBA:ARBA00022512};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1510..1543
FT /note="Gram-positive cocci surface proteins LPxTG"
FT /evidence="ECO:0000259|PROSITE:PS50847"
FT REGION 53..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1463..1517
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 53..93
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..142
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1465..1480
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1491..1505
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1543 AA; 170570 MW; DF7045095F701037 CRC64;
MKGQLFEKRS RFSIRKYTVG VCSVLIGAFL LGAPLVSADD AVASEVSSTV VEGDLGSTNI
DEVSAQDGEE TPLTPQAESS TTIENGTSTS ASTDEELVDK EVVTAPSTIE GTGETGAQTG
PAAEEPRAVE EKAVADSPVE EEKSIRPKEV KFETWTDLLN WQPGAREDDA INRASVALAE
RYRGTLVNQQ ANPDAKVQAL SNMNSKAKDH ASVGGEEFKA YAFDYWQYLD SMVFWEGLVP
SPDVIDAAHR NGVPIYGTLF YNWSDSLKDQ ERFVESLKED SEGSKTFPIA RKLVDLAKYY
GFDGYFINQE TTGRLVKPLG PKMRDFMLYT KEYARSVGYP IQYSWYDAMT YEYGRYHENA
LGEYNYQFME KNEKGDKPVD TFFANFNWNK ADVDYSINTA DYVKRSQYDV LAGLELQRGG
SYLTNVDWDA ILDANGKLRL SLGLYAPDTI TGLGKTGDGY HKHEDIFWTG YQGDPTKGKP
GDKSWYGLAN LIADRTVIIS PNFSTSFNTG HGKKWFVDGV VSKDGEWNYR SVSGILPTWR
WWIQHAEGTQ ALKGGYDFDQ AYNGGNSIAF SGKLEANSNQ HVMLYSTKIA VQDTSRLSLV
HKGGLQSEAY VTITTDPEYK TVRRYKLSPS DDWQAQTFDL SDLKGQTIYS IGLHFNSDQT
VDDFQFHLGQ LSVYSQTEKP AAPSQVSVKA KRLQNAQEAE AIIHFQGSEG ADYYEVYEQD
GDGWRIVTGS SGTTVYLAKL SRSAQAQGTK QTLKVVAVGK NGLRSDAGLV DFDWGMTTGD
TTLPRALAPN VVLGAKVIDS SFPKSEGSEG MEGMLNGTIT SLSDKWSSAQ LSGTVDIRLT
QPRTIVRWAM DHAGAGGESV DDGKMNTRDF DLYYKDADNQ WKLAKAIRGN RAHVTDVTLD
KPITAQEWRL HVITADNGTP WQAIRIYNWR MYESLDTETV NVPMKHAAVR DLGDGYLQVG
FKDVAAKTTV FVYDAPTATK AIGQGSVDEA GDLVLAPIHF DKKPNLLYYR AQTEGKELSN
ILAISVPEQE KTIASVSLEQ APTKTSYTQG EDLQLEGGLL RVRYQNGLPD ELIQLTNTAV
VVTGYKANDL GEQNLTVSYL GKTLDKGFTV QVEAKPDEEE KTVQAIGIAS LPKTEYTVGE
NLDLSEGRLK VTFEDGSSEE LSMEDQEVYV FGYDKSKEGR QTVTLLYRDQ LASFEVLVSP
KAALNDEYLK QKLAEAEKVM EKPIYSFASH ENKLALEEAV TEAQLVLEEH ETSTQAQVNE
RLNILTEALD NLDGEERFKE AVLEMTSLTA QAQEKQAHLP NHPAREGLEK AIAQVKTLLE
KDSVTPEELA DAKTSLEKAI AALDEEKRII FKDDKTGIEV HFSAKEPIAI KGLKVDVLSS
ETTKNGRLFD IEAVDADGQD IDLQYASLVR IPIEEGREVE KVLFLPENQP IQELSFEVVE
GYVVFTAPHF THYTVVYKAL DSTTDKPQDP ADKEISEPNE IQSPKKIVPL STKPLEEKKA
TKETASEQTL PETGEKASSH ALALAALGLL SASLLLVSTK KEG
//
