ID A0A139W8G9_TRICA Unreviewed; 1330 AA.
AC A0A139W8G9;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Reverse transcriptase domain-containing protein {ECO:0000259|PROSITE:PS50878};
DE Flags: Fragment;
GN Name=AUGUSTUS-3.0.2_31886 {ECO:0000313|EMBL:KXZ75569.1};
GN ORFNames=TcasGA2_TC031886 {ECO:0000313|EMBL:KXZ75569.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KXZ75569.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KXZ75569.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KXZ75569.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KXZ75569.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KXZ75569.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ973342; KXZ75569.1; -; Genomic_DNA.
DR STRING; 7070.A0A139W8G9; -.
DR EnsemblMetazoa; TC031886_001; TC031886_001; TC031886.
DR eggNOG; KOG1075; Eukaryota.
DR InParanoid; A0A139W8G9; -.
DR OMA; VECIENW; -.
DR Proteomes; UP000007266; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0071897; P:DNA biosynthetic process; IEA:UniProt.
DR CDD; cd01650; RT_nLTR_like; 1.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR043502; DNA/RNA_pol_sf.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR005135; Endo/exonuclease/phosphatase.
DR InterPro; IPR006579; Pre_C2HC_dom.
DR InterPro; IPR000477; RT_dom.
DR PANTHER; PTHR33273; DOMAIN-CONTAINING PROTEIN, PUTATIVE-RELATED; 1.
DR PANTHER; PTHR33273:SF2; PRE_C2HC DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF14529; Exo_endo_phos_2; 1.
DR Pfam; PF07530; PRE_C2HC; 1.
DR Pfam; PF00078; RVT_1; 1.
DR SMART; SM00596; PRE_C2HC; 1.
DR SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
DR PROSITE; PS50878; RT_POL; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Transposable element {ECO:0000256|ARBA:ARBA00022464}.
FT DOMAIN 951..1219
FT /note="Reverse transcriptase"
FT /evidence="ECO:0000259|PROSITE:PS50878"
FT REGION 32..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 157..182
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..449
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..61
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..102
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:KXZ75569.1"
FT NON_TER 1330
FT /evidence="ECO:0000313|EMBL:KXZ75569.1"
SQ SEQUENCE 1330 AA; 148914 MW; 0442256BA3F56B44 CRC64;
PPLTLEAIMG AMKTLLAPLS ERLQRLEEAV FSDKASEAGS TSTFTGFSAH SLKSGESQDF
METEGFSPVK TGKKRGAPSP SPVDNEIDTG NRFSSLSNED DFEPTPSDVE NGEESEMEER
RKKKKPSSPK PSPRIATWAS VAAAPKCSTS AAPRISIPAA PRVSPPTAPQ GSTPTAPISK
APRIPPIFLR DAGKWQRVSS VANERKYGFT KARSVSDQIR IQPTTVADFR SFTKFMDEEK
IPYHTFTLPE EKNTRVVLRG IPVQVSMEAV LQDLKLQGFN PVCVHRMHAG KRQLPLVLVE
APLSQTKDVW QIKTVCSLMV KVEKPRKSGK AAQCHRCQRF FHAQRNCTAE HRCVKCGEAH
DTKVCTKESK EPPKCANFPQ AAENRHPQDN RPRQDKAAPA KAAPAKAVTP KAAAPKKAAA
PKPTAAPKVV APKANPTATK GKGGAKKTAQ QRQTVTFGLQ RNQIATAVAM AKSPEELAEK
LSAFVAFWNA NGLRAARDEL EEFVDRLQLD IVLVCETKLQ PQTTDPKIRG FTLHRADRGI
GPGGGTAIFV SNRIKHSVLA TPDLRNMEAV GINVATANGP LRLFACYNRP QIPILEEDLQ
TLFDGNTPTI AAGDFNAKHI NWGSRRSNRN GNFLNGFTDQ NLDISVMAPV EPTFYRNSDG
AADILDVAIV KNVVHQVRLT AINDLSSDHN PVLMQIGNEA NDPIVCRYTS VDWRKFTKHL
VNNFGTIPPI RSKEEIDEAV QTFETKIRDA IASATRERRT PAPRLEISWE IRDLIRAKRR
ARRIAQRTGF PVDRAEANRL RWEVRKALSD FRNERWEAKL QSLTTEDNSV WRMSRVLRSD
RKPLPPIHSE NGIVFTDEEK AEAFALSMSR QCSLNLTNAD LDHVEEIEDH VESIATEDPD
EPLTPTTPEE VSGVIRKLKK RKASGPDEIS NRALKNLPLK VIVELTGILN AMFSFRYFPQ
RWKMATVIFI PKPGKDPKFP QNHRPISLLS AVGKVAERLI RTRLLQLTQE RHIVPDEQFG
FRSNHSTTDQ LLRVVEHASI SIERKQVTGA VFLDVAKAFD AVWHDGLIHK LHQTGIPLAM
VQMIRSFLVG RRFQVRINNS VSDPQDLEAG VPQGSVLSPL LYSIFTHDIP KTDRTTLAIY
ADDTAILTRS KQPYMATRYL QESVECIENW CRRWLINVNP DKSRALLLAR RRVSPDGFVR
MFNADIPWSD QVKYLGVILD KKLSFGPHLD YALAKGKMAT GMLRSLVCRR SALSIDNKLL
LYKSVIRPTM TYASVAWAFA PCKTRMHKLQ TFQNKFLRQA FNAPWFVRNN QLHREVKMPT
MEEFFRETAS
//
