ID A0A139WFJ1_TRICA Unreviewed; 1209 AA.
AC A0A139WFJ1;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Helicase SKI2W-like Protein {ECO:0000313|EMBL:KYB26733.1};
GN Name=AUGUSTUS-3.0.2_33645 {ECO:0000313|EMBL:KYB26733.1};
GN ORFNames=TcasGA2_TC033645 {ECO:0000313|EMBL:KYB26733.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB26733.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB26733.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB26733.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB26733.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB26733.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ971352; KYB26733.1; -; Genomic_DNA.
DR RefSeq; XP_008195520.1; XM_008197298.2.
DR AlphaFoldDB; A0A139WFJ1; -.
DR STRING; 7070.A0A139WFJ1; -.
DR EnsemblMetazoa; TC033645_001; TC033645_001; TC033645.
DR GeneID; 659256; -.
DR KEGG; tca:659256; -.
DR eggNOG; KOG0947; Eukaryota.
DR InParanoid; A0A139WFJ1; -.
DR OMA; CGSDITR; -.
DR OrthoDB; 1352at2759; -.
DR Proteomes; UP000007266; Linkage group 7.
DR GO; GO:0055087; C:Ski complex; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IBA:GO_Central.
DR GO; GO:0070478; P:nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay; IBA:GO_Central.
DR CDD; cd18795; SF2_C_Ski2; 1.
DR Gene3D; 1.10.3380.30; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR025696; MTR4_beta-barrel.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016438; SKI2-like.
DR InterPro; IPR012961; Ski2/MTR4_C.
DR InterPro; IPR040801; Ski2_N.
DR PANTHER; PTHR12131; ATP-DEPENDENT RNA AND DNA HELICASE; 1.
DR PANTHER; PTHR12131:SF8; HELICASE SKI2W; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF08148; DSHCT; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF13234; MTR4_beta-barrel; 1.
DR Pfam; PF17911; Ski2_N; 1.
DR PIRSF; PIRSF005198; Antiviral_helicase_SKI2; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM01142; DSHCT; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:KYB26733.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 279..435
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 543..716
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT COILED 730..757
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1094..1121
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1209 AA; 138215 MW; C95535D85B3EA5C3 CRC64;
MSDVNIDIEP PPILPDITDE LRDYLICPER LPIHRYETNQ EFWPRTPDLK ELLFFEESPL
CTTLKVQRDP NTGEIIEFRE IPIQSAGANA TNSMSLTRQP APPSEATRGN ASFIPFWPAS
FPDPVSQLPK QELLDTELLT VPPGFTRGIV FASDGRTVLS KETPREKESV EVPANVVNLF
EIIQEDPNFF GTLENANIKK PDDISEHKQR ETLPEEEEVL PNDPPILKIS TVPPPTEFKS
TEWAILLDTS KPVKDFKERI PEMAYEFPFE LDTFQKLAIL QLEQHNHVFV AAHTSAGKTV
VAEYAIALSQ KHMTRTIYTS PIKALSNQKY RDFKKEFKDV GLITGDFQIN QTASCLIMTT
EILRSMLYCG SDITRDLEYV IFDEVHYIND RERGHVWEQV LILLPAHVCV VLLSATVPNT
IEFADWLGRT HQRKVYVITT YKRPVPLLHF LYTGTGGASR DNRYLVLNSE GWKMGGYAAA
VASLPKVDPK SAYPQAKSQY YNFTPKQEKV LWNGLVDHLN RKNLLPIVAF TFSRAKCDQN
AENLMSLDLT TQKEKAQIHM FFEKCVRSLK EPDRNIPQIL RMRNILHKGI GVHHSGVLPI
IKEIVEMLFQ KGLIKLLFAT ETFAMGVNMP ARTVVFDSIT KHDGQERRNL KPAEYIQMAG
RAGRRGLDSE GTVIILCKNK IPKVEELQAM MLGTPNVLQS QFRLTYGMVL SLLRVESLSV
EGMMSRSFRE ADHQKKMVDK QNELLEVEKE IRDLCTQELS SYLQPLVKFY NCASSYLEAR
KKCLDNVMSS PKLIKVLTPG RIILITHKSH VNKLALLLSI VRGKKPTYKV LVLTDSKPEI
KEEKNDLWYK MIGLASDNIY APGSSPGHAI LTIPTEDIFE ITHKTVKVDT DLVIKDWEKR
QIERFRNDPV GQTCQQAIQE LHKFTISVNE AKNQEKLSYL HLIQDLKVNE HQIHDDLQVV
YKFKDILIDH LPSTQIPNFE QQFASVFTRT FLERKRDDLK HYLSSASLSL YPDYENRIEL
LRTLKYVDLQ NRVQLKGRVA CEMGMNELLI TELVLRNILT KLQPAEVAAL LSALVFSPKK
DNREEETVHI TDDLTKAMKE MQNIHQEIAK LEMNLDIKTD EFQNDLNFAL IEIVYEWASA
KPFADIMCLT DIQEGIIVRC IQQLNDTICD VRNAARIIGD PELQNKMEEA SAAIKRDIVF
AASLYTNDL
//
