ID A0A139WIW4_TRICA Unreviewed; 2043 AA.
AC A0A139WIW4;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Neurobeachin-like Protein {ECO:0000313|EMBL:KYB27869.1};
GN Name=AUGUSTUS-3.0.2_07591 {ECO:0000313|EMBL:KYB27869.1};
GN ORFNames=TcasGA2_TC007591 {ECO:0000313|EMBL:KYB27869.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB27869.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB27869.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB27869.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB27869.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB27869.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ971338; KYB27869.1; -; Genomic_DNA.
DR EnsemblMetazoa; TC007591_002; TC007591_002; TC007591.
DR Proteomes; UP000007266; Linkage group 4.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR010508; NBEA-like_DUF1088.
DR InterPro; IPR031570; NBEA/BDCP_DUF4704.
DR InterPro; IPR023362; PH-BEACH_dom.
DR InterPro; IPR011993; PH-like_dom_sf.
DR PANTHER; PTHR13743; BEIGE/BEACH-RELATED; 1.
DR PANTHER; PTHR13743:SF160; NEUROBEACHIN; 1.
DR Pfam; PF06469; DUF1088; 1.
DR Pfam; PF15787; DUF4704; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51783; PH_BEACH; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574}.
FT DOMAIN 1989..2043
FT /note="BEACH-type PH"
FT /evidence="ECO:0000259|PROSITE:PS51783"
FT REGION 937..1014
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1070..1270
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1538..1567
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1586..1619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 974..1014
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1071..1123
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1143..1163
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1171..1197
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1198..1212
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1217..1264
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1541..1567
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2043 AA; 230305 MW; 8D0EC5C7C0E7A507 CRC64;
MELNFVIQDA QNIRHMLELL DHCPPNLQAE IWSVFIAILR KSVRNLQACT DVGLIEHVLK
RLRNADVVVA DLLIEMLGVL ASYSITVKEL KLLFGAMKAI NGKWPRHSAK LLNVLRQMPQ
RTGPDVFFSF PGRKGSAIVL PPLAKWPYES GFTFTTWFRL DPINSVNIER EKPYLYCFKT
SKGVGYTAHF VGNCLVLTSM KIKGKGFQHC VKYEFQPRKW YMLAVVYIYN RWTKSEIKCL
VNGQLASSTE MAWFVSTNDP FDKCYIGATP ELDEERVFCG QMSAIYLFSE ALTTHQICAM
HRLGPGYKSQ FRFDNECNIN LPDNHKRVLY DGKLSSAIVF MYNPVATDSQ LCLQSAPKGN
ISYFVHTPHA LMLQDVKAVI THSIHSTLNS IGGIQVLFPL FSQLDLPYET NGSSDSKRDP
TLCSKLLGFI CELVETSQTV QQHMIQNRGF LVISFMLQRS SREHLTLDVL GSFLSLTKYL
VTCLSANSEL LLKQLLDHVL FNPALWVHTN PMVQARLYSY LSSEFLSDTQ IYSNVRRVST
VLQTIHTLKY YYWVVNPRAK SGITPKGLDG PRPDNKEIHS IRQFILLFLK QLIMIGNGVK
DDELQSILNY LTTMHENENL HDVLQMLIGL MSEHPSSMVP AFDAKHGVRT IFKLLASESQ
LIRLQALKLL GFFLSRSTHK RKYDVMSPHN LYTLLSERLL LNEDVLTIPT YNVLYEIMTE
HISQQILYTR HPEPESHFRL ENPMILKVVA TLIRQSKQTE HLLEVKKMFL SDMTLLCNNN
RENRRTVLQM SVWQEWLIAM AYIHPKNAEE QKLSDMVYSL FRMLLHHAIK YEYGGWRVWV
DTLAIVHSKV SYEEFKLQFA QMYEHYERHR ADNITDPLVR QQHPISTISG WDQQTQVSNG
CHSEEWHNSH PLQEIEAETD KSEPVCSCDY NSTMSEGSPA SYLAKHEDSE GVSLDSRTSD
LYSDVKIGKE SPFSQDSPIK SQVAEDTPES EATEGSPVCN GIHNESSPSF GSPTRISEEA
AKNEIIEEIV QEILSNSEKL LEERDVGSLS PVVQDEEIIQ AVNEVVEVTK DIPTSPEKEV
QDSESERYLT PTEETEKVCE ETDNKAKSDN ENSKLDSVSD KPTDNKISEA VPIVEISAVS
VELEPSNVES SLEANIPEPS CNDDSKNEGT ETSEVPAVEN IPTISQICDP SHYTSSEETQ
ENAHEEAKRR GSLPNGQQDG GKENQAQNSP QKRPRSASTS TQVDPNHFDN KRSKSGSSST
RPMFSPGPTR PPFRIPEFKW SYIHQRLLSD VLFSLETDIQ VWRSHSTKTV LDFVNSSENA
IFVVNTVHLI SQLADNLIIA CGGLLPLLAS ATSPNSELDV IEPTQGMPIE VAVSFLQRLV
NMADVLIFAS SLNFGELEAE KNMSSGGILR QCLRLVCTCA VRNCLECKER SRPHHTIAPT
SHNATHKAAH LQSFIRGGQN SPKTVADNLS QSTPVKDPEK LLQDMDVNRL RAVIYRDVEE
TKQAQFLSLA IVYFISVLMV SKYRDILEPP VSIRAPSPVP AIRNNGTSHS GSPQASRSVH
NQTTQEDSDY DVITEYVMED NNSVVQENDL HSGPPSIKST DSVEDINSVN SSETNNVGSN
SEITIEDNKV NNDENWTDIN LNEDGESKED TRNLQNMTEM IDIEGNIAPD RGEKHHPEIS
VVRVPDNVIQ TPAQIRPDDL PVSNLVDHIS VPTPSREASL TQKLEMALGS VCPLLREIMV
DFAPFLSKTL VGSHGQELLM EGKGLTTFKN SNSVVELVML LCSQEWQNSL QKHAGLAFIE
LINEGRLLSH AMKDHIVRVA NEAEFILNRM RADDVLKHAD FESQCAQTLM ERKEEERMCD
HLITAARRRD NVIASRLLEK IRNILSNKHG AWGYMDPAAA KLSEFWKLDA WEDDARRRKR
FVHNPLGTTH PEASLKAAIE HGAPEDAILQ AREEFHAHLA ATRNQQPIQP NDLMDDSELL
TDDRELDNDL TGPVNISTKA KLIAPGVVAP GMVSITSTEL YFEVDEEDVE FKKIDTEVSP
RDV
//
