ID A0A139WL55_TRICA Unreviewed; 2001 AA.
AC A0A139WL55;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=RZ-type domain-containing protein {ECO:0000259|PROSITE:PS51981};
GN Name=AUGUSTUS-3.0.2_34585 {ECO:0000313|EMBL:KYB28662.1};
GN ORFNames=TcasGA2_TC034585 {ECO:0000313|EMBL:KYB28662.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB28662.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB28662.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB28662.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB28662.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB28662.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
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DR EMBL; KQ971321; KYB28662.1; -; Genomic_DNA.
DR STRING; 7070.A0A139WL55; -.
DR EnsemblMetazoa; TC034585_001; TC034585_001; TC034585.
DR eggNOG; KOG1807; Eukaryota.
DR InParanoid; A0A139WL55; -.
DR OMA; ASTAPMW; -.
DR Proteomes; UP000007266; Linkage group 3.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0031380; C:nuclear RNA-directed RNA polymerase complex; IBA:GO_Central.
DR GO; GO:0004386; F:helicase activity; IEA:InterPro.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0031048; P:regulatory ncRNA-mediated heterochromatin formation; IBA:GO_Central.
DR CDD; cd06008; NF-X1-zinc-finger; 2.
DR CDD; cd18808; SF1_C_Upf1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR InterPro; IPR045055; DNA2/NAM7-like.
DR InterPro; IPR041679; DNA2/NAM7-like_C.
DR InterPro; IPR041677; DNA2/NAM7_AAA_11.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR047187; SF1_C_Upf1.
DR InterPro; IPR046439; ZF_RZ_dom.
DR InterPro; IPR000967; Znf_NFX1.
DR PANTHER; PTHR10887; DNA2/NAM7 HELICASE FAMILY; 1.
DR PANTHER; PTHR10887:SF341; NFX1-TYPE ZINC FINGER-CONTAINING PROTEIN 1; 1.
DR Pfam; PF13086; AAA_11; 1.
DR Pfam; PF13087; AAA_12; 1.
DR Pfam; PF20173; ZnF_RZ-type; 1.
DR SMART; SM00438; ZnF_NFX; 9.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51981; ZF_RZ; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 1911..1980
FT /note="RZ-type"
FT /evidence="ECO:0000259|PROSITE:PS51981"
FT REGION 20..67
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 224..259
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 743..770
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 1707..1741
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 20..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2001 AA; 229971 MW; C36FEB4450C71141 CRC64;
MYGSFNELYS GREIWNSNNW RNRNSRSGVR RNRSPSTSSE RSFPGRNRSG FVPGQQDQRG
GRRPNQNARK MGFKALQDLL NKDSEDLILE LSNIKRGIQD YIKTSLSDDG IVLFVKVLKK
VSDSAFVENK YKVLQLYLDE VFVDKLVKYV ALLPMQSDLD RTRNQFFWEN TDEFWNNVIG
ICQDIYNAIP TFGFKVLPNI LKSLLVCFPA FQDQHKQHIS DGIRDSVNKL NESLQIMIAE
EEEKKKASIQ KKVSTLIEEE PPDDFHQISV YPNSLELLGG TRVFLRKNIV EGPYKDVHHY
LDVQFRLLRE DFVGPLRNGI ATYRTESTQK QRIENVNIYK KVQFLNQETI NEQYCIRLRF
DFSRKTKKFR FEDSKKFMFG SLLCFTCDNF KSLLFGKIAQ RDVKDLEKGE LIVGFDQNVL
VDYKANYLMI ECGIYFEPYF HVLNVLKNIN TDEFPMEKYI IRVDPTPQPP EYLNDPTPRK
ISIRGHDFFP LLNWPNTNFY TFNQSQLRAF RAALTQEFSV IQGPPGTGKT FLGLKIAHTL
LQNQAIWFKK TPMLVICYTN HALDQFLEGL ALATDRIIRI GGQSRNQNVA KFNLRNIKFR
TNPAVLQQRH GVKVLLLQIQ NITENLKEID FYHSIRDFKV FIDVIPNFIT TWFHRATIDE
LLDWLLPEYE NEDLDSTNEV KSPRSVAEVQ DKVANLQIED EMFDENLSDY EIEEDENMKI
ELDDLFDEVN AMAVQCSIPL ITLSSLQQRI SALERTFQQL KQKEEITMED IFEEDRIVFE
LYKLKFRYDS LNFRLTEGKQ MRFMKRRVPD WSEFTNPHKL SPDDRWNLYF FCLNLYRQKL
NEKLSVLNEQ FREQHKIYEE MRDIENTKAM KNVLVVGMTT TGAARLRSSL QTLKSPIVIV
EEAAEILEAH IVSSLTKHCK HLILIGDHQQ LKPSTASYNI EKFYNLGISL FERMVVNRIQ
LNTLNVQHRM RPEIASLVSP TIYPTLQDHP SVNDRPDIKG VDNCLFFIDH KHPEANCEGK
SKKNYHEVDF LIYFARHLIL NGYEPGNITI LAAYLGQMFE LQKERRKHNE LLANVRIAVL
DNYQGEECDI ILLSLVRNNE ENKIGFLSIE NRVCVALSRA RNGFYLMGNM DQLCAASQLW
REIYKTFERQ NAIGPHLALR CQVHPDKVTY VASGKDFLNI SEGGCNQKCG ADLNCGHQCT
SLCHVLNRDH ASYRCLETCG KKLCDKNELH LCQRRCYQEC GPCTYKVSRT LKCGHVVNLE
CHLDPATYSC EELVPTQLPC GHNADKPCHC NPETFPCPFP CEKQVEPCGH ACTRNCHVRQ
DPDHLEYKCK KRCAKNQKNC KAEPEKHKCK KLCFEDCDAC MVRVRKQRTI CPHFYDVPCS
SNVDDISCEK PCTKILPCNH KCKNKCNQPC GNCKEKVEKQ IPVCAHTIKV KCSEEPLRKF
CTKKCPLTLP CGHPCTKKCN ESCTPTCTVL ATCALKAPCG HTVTKLPCHL AHGALDPKTL
LQHCNHPCGG QLLCEHTCSG TCGECSQGRI HKRCDAKCGN PLVCNHICEF PCRQACRPCV
RPCPYKCKHS ACGKRCGDIC VPCKESCPRR CKHRRCSKYC GEICDVPPCQ EPCSKLLACG
HQCIGFCGDP CPQKCRICDE DEVTEVFFGF EAEDDARFVL LEDCGHIFEN TGLETWLGQD
DGEVIKFKEC PRCKTAIKTT ARFSDYVKKA KADVAKVKKN LHGTENELNM KRQELARLLL
KVRTNAQDVK CSNFFKDILG AMETRLRISL MGKRQRINKF ELNAIESKLQ IIEHIVDIGI
NCPTALSKNR CSSQVKFILK ILEREDNYVT DQEIDDIPYE LNRLSRIAEL EEIESSPNFL
QRYSNSSTVR RVTEQIEGFL FGFGKFYDQD EQTVKELLQE LSRLVASGIG ISEQEKREIV
KAMGFRQGHW FKCPNGHPYC IADCGGAMVE SKCPECACKI GGGSHTLRAD NALASEMDGA
QFPAWSETAN NMGNFLLDFD D
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