ID A0A139WP38_TRICA Unreviewed; 1283 AA.
AC A0A139WP38;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Cullin-associated NEDD8-dissociated protein 1-like Protein {ECO:0000313|EMBL:KYB29760.1};
GN Name=AUGUSTUS-3.0.2_10870 {ECO:0000313|EMBL:KYB29760.1};
GN ORFNames=TcasGA2_TC010870 {ECO:0000313|EMBL:KYB29760.1};
OS Tribolium castaneum (Red flour beetle).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;
OC Tenebrionidae; Tenebrionidae incertae sedis; Tribolium.
OX NCBI_TaxID=7070 {ECO:0000313|EMBL:KYB29760.1, ECO:0000313|Proteomes:UP000007266};
RN [1] {ECO:0000313|EMBL:KYB29760.1, ECO:0000313|Proteomes:UP000007266}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB29760.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=18362917; DOI=10.1038/nature06784;
RG Tribolium Genome Sequencing Consortium;
RA Richards S., Gibbs R.A., Weinstock G.M., Brown S.J., Denell R.,
RA Beeman R.W., Gibbs R., Beeman R.W., Brown S.J., Bucher G., Friedrich M.,
RA Grimmelikhuijzen C.J., Klingler M., Lorenzen M., Richards S., Roth S.,
RA Schroder R., Tautz D., Zdobnov E.M., Muzny D., Gibbs R.A., Weinstock G.M.,
RA Attaway T., Bell S., Buhay C.J., Chandrabose M.N., Chavez D.,
RA Clerk-Blankenburg K.P., Cree A., Dao M., Davis C., Chacko J., Dinh H.,
RA Dugan-Rocha S., Fowler G., Garner T.T., Garnes J., Gnirke A., Hawes A.,
RA Hernandez J., Hines S., Holder M., Hume J., Jhangiani S.N., Joshi V.,
RA Khan Z.M., Jackson L., Kovar C., Kowis A., Lee S., Lewis L.R., Margolis J.,
RA Morgan M., Nazareth L.V., Nguyen N., Okwuonu G., Parker D., Richards S.,
RA Ruiz S.J., Santibanez J., Savard J., Scherer S.E., Schneider B.,
RA Sodergren E., Tautz D., Vattahil S., Villasana D., White C.S., Wright R.,
RA Park Y., Beeman R.W., Lord J., Oppert B., Lorenzen M., Brown S., Wang L.,
RA Savard J., Tautz D., Richards S., Weinstock G., Gibbs R.A., Liu Y.,
RA Worley K., Weinstock G., Elsik C.G., Reese J.T., Elhaik E., Landan G.,
RA Graur D., Arensburger P., Atkinson P., Beeman R.W., Beidler J., Brown S.J.,
RA Demuth J.P., Drury D.W., Du Y.Z., Fujiwara H., Lorenzen M., Maselli V.,
RA Osanai M., Park Y., Robertson H.M., Tu Z., Wang J.J., Wang S., Richards S.,
RA Song H., Zhang L., Sodergren E., Werner D., Stanke M., Morgenstern B.,
RA Solovyev V., Kosarev P., Brown G., Chen H.C., Ermolaeva O., Hlavina W.,
RA Kapustin Y., Kiryutin B., Kitts P., Maglott D., Pruitt K., Sapojnikov V.,
RA Souvorov A., Mackey A.J., Waterhouse R.M., Wyder S., Zdobnov E.M.,
RA Zdobnov E.M., Wyder S., Kriventseva E.V., Kadowaki T., Bork P., Aranda M.,
RA Bao R., Beermann A., Berns N., Bolognesi R., Bonneton F., Bopp D.,
RA Brown S.J., Bucher G., Butts T., Chaumot A., Denell R.E., Ferrier D.E.,
RA Friedrich M., Gordon C.M., Jindra M., Klingler M., Lan Q., Lattorff H.M.,
RA Laudet V., von Levetsow C., Liu Z., Lutz R., Lynch J.A., da Fonseca R.N.,
RA Posnien N., Reuter R., Roth S., Savard J., Schinko J.B., Schmitt C.,
RA Schoppmeier M., Schroder R., Shippy T.D., Simonnet F., Marques-Souza H.,
RA Tautz D., Tomoyasu Y., Trauner J., Van der Zee M., Vervoort M.,
RA Wittkopp N., Wimmer E.A., Yang X., Jones A.K., Sattelle D.B., Ebert P.R.,
RA Nelson D., Scott J.G., Beeman R.W., Muthukrishnan S., Kramer K.J.,
RA Arakane Y., Beeman R.W., Zhu Q., Hogenkamp D., Dixit R., Oppert B.,
RA Jiang H., Zou Z., Marshall J., Elpidina E., Vinokurov K., Oppert C.,
RA Zou Z., Evans J., Lu Z., Zhao P., Sumathipala N., Altincicek B.,
RA Vilcinskas A., Williams M., Hultmark D., Hetru C., Jiang H.,
RA Grimmelikhuijzen C.J., Hauser F., Cazzamali G., Williamson M., Park Y.,
RA Li B., Tanaka Y., Predel R., Neupert S., Schachtner J., Verleyen P.,
RA Raible F., Bork P., Friedrich M., Walden K.K., Robertson H.M., Angeli S.,
RA Foret S., Bucher G., Schuetz S., Maleszka R., Wimmer E.A., Beeman R.W.,
RA Lorenzen M., Tomoyasu Y., Miller S.C., Grossmann D., Bucher G.;
RT "The genome of the model beetle and pest Tribolium castaneum.";
RL Nature 452:949-955(2008).
RN [2] {ECO:0000313|EMBL:KYB29760.1, ECO:0000313|Proteomes:UP000007266}
RP GENOME REANNOTATION.
RC STRAIN=Georgia GA2 {ECO:0000313|EMBL:KYB29760.1,
RC ECO:0000313|Proteomes:UP000007266};
RX PubMed=19820115; DOI=10.1093/nar/gkp807;
RA Kim H.S., Murphy T., Xia J., Caragea D., Park Y., Beeman R.W.,
RA Lorenzen M.D., Butcher S., Manak J.R., Brown S.J.;
RT "BeetleBase in 2010: revisions to provide comprehensive genomic information
RT for Tribolium castaneum.";
RL Nucleic Acids Res. 38:D437-D442(2010).
CC -!- SIMILARITY: Belongs to the CAND family.
CC {ECO:0000256|ARBA:ARBA00007657}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; KQ971307; KYB29760.1; -; Genomic_DNA.
DR RefSeq; XP_015840644.1; XM_015985158.1.
DR RefSeq; XP_973171.3; XM_968078.4.
DR STRING; 7070.A0A139WP38; -.
DR EnsemblMetazoa; TC010870_002; TC010870_002; TC010870.
DR GeneID; 661948; -.
DR KEGG; tca:661948; -.
DR eggNOG; KOG1824; Eukaryota.
DR InParanoid; A0A139WP38; -.
DR OMA; AYIPHFQ; -.
DR OrthoDB; 68829at2759; -.
DR PhylomeDB; A0A139WP38; -.
DR Proteomes; UP000007266; Linkage group 1.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0016567; P:protein ubiquitination; IBA:GO_Central.
DR GO; GO:0010265; P:SCF complex assembly; IBA:GO_Central.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR039852; CAND1/CAND2.
DR InterPro; IPR013932; TATA-bd_TIP120.
DR PANTHER; PTHR12696:SF0; CULLIN-ASSOCIATED NEDD8-DISSOCIATED PROTEIN 1; 1.
DR PANTHER; PTHR12696; TIP120; 1.
DR Pfam; PF08623; TIP120; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000007266};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 1091..1254
FT /note="TATA-binding protein interacting (TIP20)"
FT /evidence="ECO:0000259|Pfam:PF08623"
FT REGION 359..386
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 366..385
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1283 AA; 144815 MW; B7832B687AAB5912 CRC64;
MAEEQQQGDE SNPYEQGDHA FELDDLERAL VTCELRSYVD QVVEDAAEMA SVSYQIANLL
EKMQSSDKDF RFMATNDLMA ELQKDSIKLD DDSERKVVRM LLKLLEDKNG EVQNLAVKCL
GPLVNKVKEF QVETIVEALC TNMVSDKEQL RDISSIGLKT VIAELPQAPG GLSGNICKRI
TGRLTTAIER QDDVSVQLEA LDIVTDLLYR FGNVLQSYHA SILNALLPQL CSQRQAVRKR
TIAACSNLVL SCNNALYDKL IEHLYNGMRT DNKNSQIRTY VQCIAAVCRQ SGHKFGEHIE
KFVPLIQMWS AVEDDETREF CLQAFESFIN RCPKEITPKI SAITDLCLNY MTHDPNYNYD
EDGDDRAMGA YDDEEEEEND EYSDDDDMSW KVRRAAAKCL ESIICTRHEL LSEFYKVLSP
VLISRFKERE ENVKSDIFRA YIALLRQTKS TVNVNIDPNS MEQEEMPIYL LQQQVPMIVK
GVQSQMKEKS TKTRQDCFQL LKELCNVLPG ALTHHIGDLI PGILFSLSEK NGSSNMKIDG
LSFLLCLLAS HPPEVFHPHI NILLPHIIAN VGDNFYKITA EALNVLKELV KVIRPLDRDS
NFDFTPFVKE IYLCTLSRLK TSDLDQEVKE KAISTMGQII CNLGDHLGSE LSCCLPLFLD
RLRNEITRLT TVKALTKIAG SPLGIELPIL DEAVPVLGLF LRKNQRALKL STLQLIDCLI
KNYHVYMYVE LLQHVIVEVP PLLDESDLHI AQYTLVILKS IAEYHPLALQ DLPTNIFPQI
LVLVKSPLLQ GSALNSMLEF FKTLVQCNLP GLSYNDLLQF LVHPISISQG SGAGDAVIHK
QAYYSLAKCV AAITVTMQHQ ALQIVPQFIN EIRSSRHDAQ KIFTLLVVGE IGREIDLTGF
ANLEQIISEA FFAVSEEVKS AASYALGSIA IGNLQQYLPF ILTEDENEPR RQYLLLHSLK
EVIACLSSTP EGIQQLLPFV PAIWDTLYRH CESEEEGTRN VVSECLGKLT LIDPNHLLPK
LKESLGSESS LMRTTIVTAI KFTISDQPAS IDALLRQCIG EFLNTLEDPD LNVRRVALVA
FNSAAHNKPS LIRDLLDTIL PRLYHETNIK RELIREVEMG PFKHTVDDGL DLRKAAFECM
YTLLDSCLDR IDIFEFINHV ELGLKDHYDI KMLTYLMVSR LAQICPGAVL QSLDRLVEPL
KATCTMKVKA NSVKQEYEKQ DELKRSALRA VVSLLSIPDA DKNQHLNEFV TQIKTSPDLA
QIFDSIQKDS ANNINDFFLM DQS
//
