ID A0A139X083_9CYAN Unreviewed; 402 AA.
AC A0A139X083;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=Nucleoside permease {ECO:0000256|RuleBase:RU362018};
GN ORFNames=WA1_37840 {ECO:0000313|EMBL:KYC38115.1};
OS Scytonema hofmannii PCC 7110.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Scytonemataceae;
OC Scytonema.
OX NCBI_TaxID=128403 {ECO:0000313|EMBL:KYC38115.1, ECO:0000313|Proteomes:UP000076925};
RN [1] {ECO:0000313|EMBL:KYC38115.1, ECO:0000313|Proteomes:UP000076925}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7110 {ECO:0000313|EMBL:KYC38115.1,
RC ECO:0000313|Proteomes:UP000076925};
RX PubMed=23221676; DOI=10.1093/gbe/evs117;
RA Dagan T., Roettger M., Stucken K., Landan G., Koch R., Major P.,
RA Gould S.B., Goremykin V.V., Rippka R., Tandeau de Marsac N., Gugger M.,
RA Lockhart P.J., Allen J.F., Brune I., Maus I., Puhler A., Martin W.F.;
RT "Genomes of Stigonematalean cyanobacteria (subsection V) and the evolution
RT of oxygenic photosynthesis from prokaryotes to plastids.";
RL Genome Biol. Evol. 5:31-44(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the concentrative nucleoside transporter (CNT)
CC (TC 2.A.41) family. {ECO:0000256|ARBA:ARBA00009033,
CC ECO:0000256|RuleBase:RU362018}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362018}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYC38115.1}.
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DR EMBL; ANNX02000042; KYC38115.1; -; Genomic_DNA.
DR RefSeq; WP_066613156.1; NZ_KQ976354.1.
DR AlphaFoldDB; A0A139X083; -.
DR STRING; 128403.WA1_37840; -.
DR OrthoDB; 9766455at2; -.
DR Proteomes; UP000076925; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005337; F:nucleoside transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR008276; C_nuclsd_transpt.
DR InterPro; IPR018270; C_nuclsd_transpt_met_bac.
DR InterPro; IPR011657; CNT_C_dom.
DR InterPro; IPR002668; CNT_N_dom.
DR InterPro; IPR011642; Gate_dom.
DR NCBIfam; TIGR00804; nupC; 1.
DR PANTHER; PTHR10590; SODIUM/NUCLEOSIDE COTRANSPORTER; 1.
DR PANTHER; PTHR10590:SF4; SOLUTE CARRIER FAMILY 28 MEMBER 3; 1.
DR Pfam; PF07670; Gate; 1.
DR Pfam; PF07662; Nucleos_tra2_C; 1.
DR Pfam; PF01773; Nucleos_tra2_N; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362018};
KW Reference proteome {ECO:0000313|Proteomes:UP000076925};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362018};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362018}; Transport {ECO:0000256|RuleBase:RU362018}.
FT TRANSMEM 31..47
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 86..108
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 163..185
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 286..304
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 341..369
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362018"
FT DOMAIN 8..80
FT /note="Concentrative nucleoside transporter N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01773"
FT DOMAIN 88..186
FT /note="Nucleoside transporter/FeoB GTPase Gate"
FT /evidence="ECO:0000259|Pfam:PF07670"
FT DOMAIN 191..399
FT /note="Concentrative nucleoside transporter C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07662"
SQ SEQUENCE 402 AA; 42880 MW; C4C05E7A2D2AE63B CRC64;
MERTISALGL FVFIGISYIF SVNRRAVRWR TVAWGLGLEF LFALLILKTP SGLTAFKSLG
DVVTSFLGFS DVGAKFVFGE SYKDHLFAFQ VLPTIIFFSA FISVLYHYGI LQWTVTGIAW
VMMKTMKTSG SESLSCAGNI FLGPTESPLI VKPYVPTMTQ SELFAVMTGG FATVAGGTLG
AYLSFGLPTE HLIAAFFMTA PTSLVVAKLL YPETEVSDTA GQVRVKVKTN FVNVIDAAAS
GALDGARLAV NVGVMIIAFL GLLAVVNALL GWLGTLFGLP QLSLEWILSF IMAPVALFMG
VPLADCGQVG VLLGKKTILN EFIAYLDLKT LIEKGQISQR AIVIATYALC NFANVGSIAI
TIGGITGMAP TRQHDLARMG VRSMIGGLLA GFMTACIAGM LV
//
