ID A0A139XDB5_9CYAN Unreviewed; 5742 AA.
AC A0A139XDB5;
DT 11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT 11-MAY-2016, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Carrier domain-containing protein {ECO:0000259|PROSITE:PS50075};
DE Flags: Fragment;
GN ORFNames=WA1_15575 {ECO:0000313|EMBL:KYC42612.1};
OS Scytonema hofmannii PCC 7110.
OC Bacteria; Cyanobacteriota; Cyanophyceae; Nostocales; Scytonemataceae;
OC Scytonema.
OX NCBI_TaxID=128403 {ECO:0000313|EMBL:KYC42612.1, ECO:0000313|Proteomes:UP000076925};
RN [1] {ECO:0000313|EMBL:KYC42612.1, ECO:0000313|Proteomes:UP000076925}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=PCC 7110 {ECO:0000313|EMBL:KYC42612.1,
RC ECO:0000313|Proteomes:UP000076925};
RX PubMed=23221676; DOI=10.1093/gbe/evs117;
RA Dagan T., Roettger M., Stucken K., Landan G., Koch R., Major P.,
RA Gould S.B., Goremykin V.V., Rippka R., Tandeau de Marsac N., Gugger M.,
RA Lockhart P.J., Allen J.F., Brune I., Maus I., Puhler A., Martin W.F.;
RT "Genomes of Stigonematalean cyanobacteria (subsection V) and the evolution
RT of oxygenic photosynthesis from prokaryotes to plastids.";
RL Genome Biol. Evol. 5:31-44(2013).
CC -!- COFACTOR:
CC Name=pantetheine 4'-phosphate; Xref=ChEBI:CHEBI:47942;
CC Evidence={ECO:0000256|ARBA:ARBA00001957};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:KYC42612.1}.
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DR EMBL; ANNX02000019; KYC42612.1; -; Genomic_DNA.
DR RefSeq; WP_066612897.1; NZ_KQ976354.1.
DR STRING; 128403.WA1_15575; -.
DR OrthoDB; 9757538at2; -.
DR Proteomes; UP000076925; Unassembled WGS sequence.
DR GO; GO:0016874; F:ligase activity; IEA:UniProtKB-KW.
DR GO; GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
DR CDD; cd05930; A_NRPS; 1.
DR CDD; cd17643; A_NRPS_Cytc1-like; 1.
DR CDD; cd17651; A_NRPS_VisG_like; 1.
DR CDD; cd19543; DCL_NRPS; 2.
DR CDD; cd19534; E_NRPS; 2.
DR CDD; cd19531; LCL_NRPS-like; 3.
DR Gene3D; 3.30.300.30; -; 4.
DR Gene3D; 3.40.50.980; -; 8.
DR Gene3D; 1.10.1200.10; ACP-like; 4.
DR Gene3D; 3.30.559.10; Chloramphenicol acetyltransferase-like domain; 7.
DR Gene3D; 1.10.10.1830; Non-ribosomal peptide synthase, adenylation domain; 1.
DR Gene3D; 3.30.559.30; Nonribosomal peptide synthetase, condensation domain; 7.
DR InterPro; IPR010071; AA_adenyl_domain.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR023213; CAT-like_dom_sf.
DR InterPro; IPR001242; Condensatn.
DR InterPro; IPR010060; NRPS_synth.
DR InterPro; IPR020806; PKS_PP-bd.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR006162; Ppantetheine_attach_site.
DR InterPro; IPR041464; TubC_N.
DR InterPro; IPR044894; TubC_N_sf.
DR NCBIfam; TIGR01733; AA-adenyl-dom; 4.
DR NCBIfam; TIGR01720; NRPS-para261; 2.
DR PANTHER; PTHR45398; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR PANTHER; PTHR45398:SF1; ENZYME, PUTATIVE (JCVI)-RELATED; 1.
DR Pfam; PF00501; AMP-binding; 4.
DR Pfam; PF13193; AMP-binding_C; 4.
DR Pfam; PF00668; Condensation; 7.
DR Pfam; PF00550; PP-binding; 4.
DR Pfam; PF18563; TubC_N; 1.
DR SMART; SM00823; PKS_PP; 4.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 4.
DR SUPFAM; SSF47336; ACP-like; 4.
DR SUPFAM; SSF52777; CoA-dependent acyltransferases; 14.
DR PROSITE; PS00455; AMP_BINDING; 3.
DR PROSITE; PS50075; CARRIER; 4.
DR PROSITE; PS00012; PHOSPHOPANTETHEINE; 4.
PE 4: Predicted;
KW Phosphopantetheine {ECO:0000256|ARBA:ARBA00022450};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000076925}.
FT DOMAIN 1069..1143
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 2610..2685
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 3701..3776
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT DOMAIN 4776..4850
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT NON_TER 5742
FT /evidence="ECO:0000313|EMBL:KYC42612.1"
SQ SEQUENCE 5742 AA; 644607 MW; 36D445917AE77C08 CRC64;
MSNSTFEFLY QLRNLGINLE TDGSRLRCHA PEGVLTPTLS QEIARRKTEI ILLLQEAKQV
QEAKQVKASD NFSIQRVPRD GQLPLSFSQQ RLWFVQQMSP DSTAYNMVEA LRLQGSLNIV
ALEQSLSELI RRHEVLRTTF PTVEGNPTQL IAPPTALTLP IHNLQGLSTQ EQTAQIRQMT
QSLASKPFDL AVESSIQFTL LQLSEQEYVL LLKMHHIIYD GWSLNIFFSE LCQLYEAFTQ
GLPNPLAPSH IQYADFAVWQ RKWLTGVVLD RQLNYWQQQL AGIPSILELP ADRQRSPVQT
FRGGVERFQL DRDLTQRLKE LSQESDATLF ITLLAAFLVL ISRYTGQSDL VVGSPIANRN
KLEFEQLVGF FANTLVLRGN LSGNPTFRDF HAQVRQTTLS AYAHQDLPFE MLVEKLQPVR
DLSRNPLVQV VFALQNTPQS SSNLPGLTIQ NMPLSLDITA NFDLEVNYLE NSEGLEGIWR
YSSDLFDATT ITRIAQHFEN LLRAIVANPE ARISELPLLS QAERDRLLVE WNNTEVDYPR
DKCIHQLFEE QVERTPNAVA VVCDNKQLTY NELNSRANQL AHYLQSLGVG ADVLVGICVE
RSIEMVVGLL SILKAGGAYV PIDPDYPSER KNFILADTQT AILLTQQHLA QNLPTDGIQV
ICLDRDWKAN IQQPICNPVS ETNALHLAYV IYTSGSTGKP KGTLITHQGL VNYLSWCTQA
YGVKQGGGTI VHSPLGFDLT VTSLFSPLLV GNQVEILSQD QAVETLSHAL RHHSHLSLVK
ITPAHLELLN QQISPKEAAN RTRAFIIGGE NLLAENIAFW QEFAPETKLV NEYGPTETVV
GCCIYEVPTG QHRSGSIPIG RPIANTQLYI LDEYLQPVPI GVPGELHIGG MGLARGYLNR
PELTEEKFIP NPFRRSRGAQ EHRSWVLKED QSCSERLYKT GDLARYLPDG NIEYLGRIDN
QVKIRGFRIE LGEIEAVLSQ HEHVQSTVVI AREDIPSNKR LVAYIVPQKQ VTPTLNELRS
FLKEKLPDYM VPSVLVLLES LPLTPNGKVD QRALPIPESR TGIEDKFVAP RTPVEAKLAE
IWAQVLRVEA VGIHDNFFSL GGDSILSIQI IAKAKLAEIE LSLKQLFANQ TIAELATVAL
TTKALFIEQG LVTGASLLTP IQQWFFEQQL PQAHHYNQSF LLTVPDDIKI EFLERVWKEL
LTHHDALRLR FTQTESNWQQ VHAENCDRNV ISCFDLSTLP DSEQQRAIEN TANSLQASLN
LSENLVQVAL FRLGVDKKSR LLIIIHHLVV DGVSWRILLE DLVTGYSQLC EGKAIQLPAK
TTSFKDWAQH LREYAQSHHL KSELDYWLNV SNTAVTPLPV DHADGANTVA STCTVSVSLN
SSETQALLKD VPKAYKTQIN DVLLTALVLV VSRWADSKSV LFNLEGHGRE EIIDGIDLSR
TVGWFTTIFP VVLKLTDTEN LGKVLKSVKE QLRAVPNKGI GYGVLRYLNQ DIVQSAQLAT
IPNAQISFNY LGQFTQVLNT ESLISLAVES SGQNQSLQGQ RSTSLDINAI IADQQLQIHW
TYSRNLHEQT TIEHLASEFV CELQNLIAHC LEPDNVGYTP TDFPLIRLNQ SELDLVLARL
ASQSQLSQIH WQNLEDMYPL SPMQAGMLFE SLYAPDTGVY FEQIACTFAG NLNVRAFEQA
WQMVVARHSI FRTAFEWESL STPVQVVYRQ LDVKVNTLDW RALSTIEQKE RLETFLLDER
KQGFQLHQAP LMRLHLLRLD ENTYQFVWCH HHILLDGWSL PLVFQDLFAF YQAICDGENV
SLPPTVNYRN YIAWLQQQDL NSAKEFWQQK LLGFSTPTPL RVDKPLSQRQ QHSRYDEQHI
YLSALATSQA VDFVKQHQLT LNNLVQVTWG LLLSRYSGET DVVFGATLSG RPPALLGVES
MVGIFINTVP VRWQISPQTD LLSLLKDLQT QQVESEQFSY CSLVEIQSLS DIPRGTSLFE
SIVVFENYPV DADTLQDDGG LTVADFRGIE HANYPLTVVA GPGEQLWLKV SYDTNQFEHG
TINRMLGHFV TLLSAIVANP HQPIEQLPLL TASEQQQLLL AWNDTQLDSA VDKCIHQLFE
AQVALTPNAV AVVFEDQQLT YNELNSRANQ LAHELRSLGV GADVLVGICV ERSLSAIVGL
LAILKAGGAY VPLDPESPTE RMSFVLQDTQ LSVLVTQQHL VAKFPSIQAR VLCLDSDWHH
IARNSAANPL NGTTPTHLAY VIYTSGSTGL PKGVLVNHNC VTRLFAATQP WYDFNSQDVW
TLFHSIAFDF SVWEIWGALL YGGRLVVVPY LVTRSPESFY QLLSQQKVTI LNQTPSAFRQ
LMQAEQSMAT VTNLSLRLVI FGGESLEINS LHPWFERHGD RHPQLVNMYG ITETTVHVTY
RPLSKDDFHS TLSLIGRPIP DLQVYVLDEH QRLVPIGVPG EMYVGGAGVS RGYLNRPELT
AQRFISHPFH NSTGGDRLYK TGDLARYLPN GELEYLGRID NQVKIRGFRI ELGEIEALLS
QHHHVQANCV IVREDTPGDL RLVAYIVPHI DHAPTPNSLR SFLKQKLPDY MVPNAIVLLE
SLPLTNNGKV DRRALKAPEP SHELSDKFVA PRTPTEEMLA QLWAQVLKVK AVGRYDNFFE
LGGHSLLATQ LVSRIRNVFK VELPLRSLFA TPTVAGLAQE IQQLQQENVE LTYTPVLPRA
ENAELPLSFA QQRLWFLDRL EPLSASYNIP MALRLQGTLC VAALEQSLVE IIHRHESLRT
NFITVDGQAT QLIHTDLNWT VSVVDLQHLS PTEQEIAAQQ LAQQQALEPF DLSNATLLRA
TLVVLSQTEH VLLVCMHHIV SDGWSIGVFV EELAALYNAY CEGKPSPLAP LPIQYADFAI
WQRQWLQGDI LQNQLNYWLQ QLEYAPTFLP LPTDRPRDAV QTFAGAYLEF ALSLELTQKL
THLSQEQGCT LFMTLLAAFD TLLYRYTGQS DILVGSPIAN RHRSEIEGLI GFFVNTLVLR
ADLSSNPSFN ELLTRIRSMA MSAYAHQDLP FEMLVEALQP ERDLSHTPLF QVMFVLQNAP
TSVVELTGLT VSSLPVETTT AKFDLTLSMK NTPTGLVSGW EYNTDLFDGS TIERMIEHFV
TLLEAIVANP SERIDQLPLL TPTEQQRLLV EWNNTQVDYP VDKCIHQLFE EQVARTPDAV
AVEFGNQQLT YYELNCRANQ LAHYLRSAKL SRSDSLGVGA DVLVGICVER SLSMVVGLLG
ILKAGGAYVP LDPEYPTERL SFMVEDARVQ VLLTQRSLSE RLPQHTAQLV YLDAEAELVS
QFSQNNVISG VQANHLGYVI YTSGSTGQPK GVAMSQRALC NLIFWQVKNL KLSRGAKTLQ
FAPIGFDVSF QEMFSTWYSG GTLLLISEEL RRDAVALLAL IEDKAIERLF IPFVGLQQLA
EVAVGGKLFT SHLREIMTAG EQLQMTPAIC NWLSQLTDCT LHNHYGPSES HVVTTFTLSD
SANSWSLLPP IGRPIANTQI YILDRYLQPV PIGVPGELHI GGASLARGYF NRPELTQEKF
IPNPFRRSRG AGEHRSWGVK EDQSCSERLY KTGDLARYLP DGNIEYLGRV DNQVKIRGFR
IELGEIEAAL SQHEDVQANC AIAREDTPGD LRLVAYIVPQ TQVTPTISQL RQFLKEKLPE
YMVPNAFVFL ETLPLTPNGK VNRRALPTPD KHSELQEKYV APCTPTEEML AQLWAQVLKV
EAVGRYDNFF ELGGHSLLAT QLVSRIRNVF KVELPLRSLF VTPTVAELAQ EIQQLQQENV
KLVYTPILPR SENAELPLSF AQQRLWFLDR LEPLSASYNI SAALRLQGTL YVAALEQSLV
EIIHRHEALR TNFITVDGKA TQLIHTDLNW TVSVVDLQQL CPSEQEIAAQ QLAQQQALEP
FDISNAILLK ATLVVLSQTE HVLLVCMHHI VSDGWSIGVF VEELATLYNA YCEGKPSPLA
PLPIQYADFA IWQRQWLQGD ILQNQLSYWL QQLEYAPTFL PLPTDRPRGA VQTFNGAYLE
FALSVELTQK LTRLSQEQGC TLFMTLLAAF DTLLYRYTGV ADILVGSPIA NRHRSEIESL
IGFFVNTLVL RADLSGNPSF NELLTRIRSM AMSAYAHQDL PFEMLVEAVQ PERDLSHTPL
FQVMFVLQNA PTSVVELSGL TVSSLPIETA TTKFDLTLSM ENTPIGLVGG WEYNTDLFDG
STIERMIGHF VTLLEAIVAN PNEQISQLPL LTLTEQQQLL VEWNDTRVDY PVDKCIHELF
EEQVARTPNA VAIVFENQQL TYSELNSRAN QLAHYLRSRG VGANVLVGIC VERSLSMVVG
LLAILKAGGA YVPLDPEYPQ DRLSFMLEDA QVSVLLTQQH LVEKFPSHPA QVVCLDTHWQ
LVSQFSGENP ATVVRATDLA YTIYTSGSTG TPKGVPIAYE GLLNLVFWHQ RTFDLASSDR
ATQLAGTGFD AAVWEIWPYL TRGATLYLVK SELVTEPENL QQWLIDNKIT ITFVPTPVAI
ELLSLEWKTQ SSALRYLLTG GDRLQQYPSA SVPFSVVNNY GPTENTVVTT SGLVVAREQL
QISPPIGRPI ANTQVYILDK YLQPVPIGVP GELHIGGASL ARGYLNRPEL TQEKFIPNPL
RRSRGAQEHR SSVLKEDQSC SERLYKTGDV ARFLSDGNIE YLGRIDNQVK IRGFRIELGE
IEAVLRQYPQ VRSSCVIARV DIPGNKRLVA YIVPQKQVTP TLNELRSFLK EKLPDYMVPN
AIVLLESLPL TPNGKVDRRA LPIPESRTGI EDKFVAPRTP VEAKLAEIWA QVLRVEAVGI
HDNFFELGGD SILSIQIIAK AKLAGIELSL KQLFANQTIA ELATVALTTK ALFIEQGLVT
RASPLTPIQQ WFFEQQLPQS HHFNQSFLLT VPTDINIKFL EVVWKELLKH HDALRLRFTQ
TESNWLAIHA APTDSMGICC YDLSTLPESE QQRAMESTAN LLQASLNLSE NLVQVALFRL
GVDKKARLLI IIHHLVVDGV SWRILLEDLV TGYCQLCEGK AIQLPAKTTS FKDWAQHLRE
YAQSNHLKSE LDYWLNVSNT AVTPLPVDYA DGANTVASTC TVSVSLNSSE TQALLQDVPK
AYKTQINDVL LTALLLVVSR WTDSNSVLFN LEGHGREDII EGVDLSRTVG WFTTMFPVVL
KLSDTNNLGK VLKSVKEQLR AIPNKGIGYG LLRYLNEDVV RSAQLAKVPK AQISFNYLGQ
FTQVLNTESL ISLASESSGQ FQSLQGQRST SLDINAIIAD QQLQIHWTYS CNLHAQTTIE
HLASEFVCEL QNLIAHCLEP DNVGYTPTDF PLIRLNQSEL DLVLAKVASN AQLSQIHWQN
LEDIYPLSPM QAGMLFESLY APNTGVYFEQ IACTFAGNLN VRAFEQAWQM VVARHSIFRT
AFEWESLSTP VQVVYRQLDV KVNTLDWRGL TKTEQQEQLE TFLDEEQKQG FQLHQAPLMR
LHLLRLDENT YQFVWCHHHI LLDGWSLPLV FQDLFAFYQA ICDGENVSLP PTVNYRNYIA
WLQQQDLNSA KEFWQQKLLG FSTPTPLRVD KPLSQRQQHS RYDEQHIYLS ALATSQAVDF
VKQHQLTLNN LVQVTWGLLL SRYSGETDVV FGATLSGRPP ALLGVESMVG IFINTVPVRW
QISPQTDLLS LLKDLQTQQV ESEQFSYCSL VEIQSLSDIP RGTSLFESIV VFENYPVDAD
TLQDDGGLTV ADFRGIEHAN YPLTVVAGPG EQLWLKVSYD TN
//
