ID   A0A140DWV4_9FIRM        Unreviewed;       704 AA.
AC   A0A140DWV4;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Membrane transport protein MMPL domain-containing protein {ECO:0000259|Pfam:PF03176};
GN   ORFNames=AALO17_19970 {ECO:0000313|EMBL:AMK55131.1};
OS   Faecalibaculum rodentium.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Erysipelotrichaceae; Faecalibaculum.
OX   NCBI_TaxID=1702221 {ECO:0000313|EMBL:AMK55131.1, ECO:0000313|Proteomes:UP000069771};
RN   [1] {ECO:0000313|EMBL:AMK55131.1, ECO:0000313|Proteomes:UP000069771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Alo17 {ECO:0000313|EMBL:AMK55131.1,
RC   ECO:0000313|Proteomes:UP000069771};
RX   PubMed=26877770; DOI=10.1186/s13099-016-0087-3;
RA   Lim S., Chang D.H., Ahn S., Kim B.C.;
RT   "Whole genome sequencing of "Faecalibaculum rodentium" ALO17, isolated from
RT   C57BL/6J laboratory mouse feces.";
RL   Gut Pathog. 8:3-3(2016).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
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DR   EMBL; CP011391; AMK55131.1; -; Genomic_DNA.
DR   RefSeq; WP_067558419.1; NZ_CP011391.1.
DR   AlphaFoldDB; A0A140DWV4; -.
DR   STRING; 1702221.AALO17_19970; -.
DR   GeneID; 78478602; -.
DR   KEGG; fro:AALO17_19970; -.
DR   PATRIC; fig|1702221.3.peg.1944; -.
DR   OrthoDB; 9782006at2; -.
DR   Proteomes; UP000069771; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR004869; MMPL_dom.
DR   PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR   PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR   Pfam; PF03176; MMPL; 2.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000069771};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        176..193
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        226..247
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        268..295
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        301..327
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        354..373
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        520..539
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        546..566
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        572..592
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        622..640
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        652..679
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          42..331
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
FT   DOMAIN          386..689
FT                   /note="Membrane transport protein MMPL"
FT                   /evidence="ECO:0000259|Pfam:PF03176"
SQ   SEQUENCE   704 AA;  77121 MW;  DBCE4CA6AD65996D CRC64;
     MEQLSRFIVK HRNAILLVAV LLLIPSIFGY LNTRVNYDLL SYLPKDTESM KAQDVLGDDF
     NLSSVDMLVV NGMPEKDVAK LKTQIEGIDG VDKVIWRDSV LDLSVPREAI PESIQDMLYS
     GDSTMLIITF REPTASDRTM NAIAQIKQYS QMDCWLAGFS AITEDTRDLV TTETPIYSAI
     AVALCLVVLC LGLESWVAPF VFLLGIAFPI IYNMGTNIFL GEISYITKAL ALILQLAVTM
     DYSIFLLHRY QEEKAKPGVT NEEAMASAIQ ATFVSITSSS ITTIAGFLAL CFMSLTLGKD
     IGLVMAKGVV LGVICTVLVL PSLIMFFDKW IEKWKHPVLI RPVKKAPVFV TKHYKAIIAV
     FVLLFIPAIY AQANVAQYYD LTATLPEDMA SVQGTTQMKE KFNMNTTHFV LVDDKVSARD
     MQDMISQMEE VKGVSNVLAY EKYIGPGVPS TFEPAQLEDI LHNGGRRLVV VNSEYRGATD
     EENKQLDTLR EILHKYDKNG LIGGEGALDE DLIKVTNVDF QMVNIVSIVA ILAIIAVTFK
     SLSLPFILVL AIEFAISVNM GIPFFTHTTL PFIASIVIGT IQLGACIDYA ILITSRFREE
     LQNGQTPVRA IQISVEKSST SIITSGLSFF AACTGVAMIA KMDMIASLCT LLGRGALISV
     LVILFILPAL LLACSGLIAK TTKGWPKASA RAASSKSGKE AARA
//