ID   A0A140DXE8_9FIRM        Unreviewed;       754 AA.
AC   A0A140DXE8;
DT   11-MAY-2016, integrated into UniProtKB/TrEMBL.
DT   11-MAY-2016, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   RecName: Full=Pyruvate formate-lyase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=AALO17_21910 {ECO:0000313|EMBL:AMK55325.1};
OS   Faecalibaculum rodentium.
OC   Bacteria; Bacillota; Erysipelotrichia; Erysipelotrichales;
OC   Erysipelotrichaceae; Faecalibaculum.
OX   NCBI_TaxID=1702221 {ECO:0000313|EMBL:AMK55325.1, ECO:0000313|Proteomes:UP000069771};
RN   [1] {ECO:0000313|EMBL:AMK55325.1, ECO:0000313|Proteomes:UP000069771}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Alo17 {ECO:0000313|EMBL:AMK55325.1,
RC   ECO:0000313|Proteomes:UP000069771};
RX   PubMed=26877770; DOI=10.1186/s13099-016-0087-3;
RA   Lim S., Chang D.H., Ahn S., Kim B.C.;
RT   "Whole genome sequencing of "Faecalibaculum rodentium" ALO17, isolated from
RT   C57BL/6J laboratory mouse feces.";
RL   Gut Pathog. 8:3-3(2016).
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DR   EMBL; CP011391; AMK55325.1; -; Genomic_DNA.
DR   RefSeq; WP_067560231.1; NZ_CP011391.1.
DR   AlphaFoldDB; A0A140DXE8; -.
DR   STRING; 1702221.AALO17_21910; -.
DR   GeneID; 78478766; -.
DR   KEGG; fro:AALO17_21910; -.
DR   PATRIC; fig|1702221.3.peg.2131; -.
DR   OrthoDB; 9803969at2; -.
DR   Proteomes; UP000069771; Chromosome.
DR   GO; GO:0016829; F:lyase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.20.70.20; -; 1.
DR   InterPro; IPR019777; Form_AcTrfase_GR_CS.
DR   InterPro; IPR001150; Gly_radical.
DR   InterPro; IPR004184; PFL_dom.
DR   PANTHER; PTHR43641:SF2; DEHYDRATASE YBIW-RELATED; 1.
DR   PANTHER; PTHR43641; FORMATE ACETYLTRANSFERASE 3-RELATED; 1.
DR   Pfam; PF01228; Gly_radical; 1.
DR   Pfam; PF02901; PFL-like; 1.
DR   SUPFAM; SSF51998; PFL-like glycyl radical enzymes; 1.
DR   PROSITE; PS00850; GLY_RADICAL_1; 1.
DR   PROSITE; PS51149; GLY_RADICAL_2; 1.
DR   PROSITE; PS51554; PFL; 1.
PE   4: Predicted;
KW   Lyase {ECO:0000256|ARBA:ARBA00023239};
KW   Organic radical {ECO:0000256|ARBA:ARBA00022818, ECO:0000256|PROSITE-
KW   ProRule:PRU00493}; Reference proteome {ECO:0000313|Proteomes:UP000069771}.
FT   DOMAIN          2..631
FT                   /note="PFL"
FT                   /evidence="ECO:0000259|PROSITE:PS51554"
FT   DOMAIN          638..754
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000259|PROSITE:PS51149"
FT   MOD_RES         731
FT                   /note="Glycine radical"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00493"
SQ   SEQUENCE   754 AA;  84867 MW;  D27489279D1078C7 CRC64;
     MKHINIDGAQ NVEVSRKLPS EKTPARQLDM MERYTEVYRS HLNDDKSLRE VKCLEVIYPG
     LFRHLQKGDL IAGRLDFLPI GFGCVTSVGG VGHYCVFHKL RGLKDQLPES DWPRIDALYD
     FWQDHDLKTL YCQDVLDETT TGRFIDCAYP YMATARLSGM MLDYTKLMRL GVPGLKREIA
     ERLAADQGNG YLQASLEMMD LFVKVIRAQK DLVADSGDVP MEAKQRMIGD LTAIEDNPPQ
     TFRQALQLFW LYALCAGCIN YGRLDIVLGP FLKADIEAGI ETEDSAQAVL ESLWMLIENR
     RTTVNGRIIV GGRGRPDPEA ADLFAKICLR VVKKLRCVEP QFTFRFDAET DPALKDMAYE
     CIAAGATYPT LYNDDVNIPA VQYAMRVDRK TAEQYLPFGC GEFVIQGQSL GTPNTLLNMV
     KVLQIAMNEG VDPMDGKQKN GPVQLKPLVD LTTFEAFYDQ YKKMLDWYFE KCARDQLYSY
     EVMNREVSFL FASALMDDCL ARGKALLDGG VKILGGTLET YGNINASDAL TAIRRLVFEE
     KKYTLEEMNA AANRDFQGDA VMLRDILAVP KYGNDEQEAD DMADDLYEFT AKSVRQKGID
     LGMDYFLIVI SNNQTNTDWG LQTAASLDGR RRGVYMNPAN NPQGGAATSG PTAVLNSLSR
     FDAKYHGGSV QNIKFTPRMM HEDKEKVKIL FDTYFRKGGC QLMVTVVDKG QLEDAQKHPE
     KYPDLIVRVA GYSAVFVDLD KTVQDELLSR ALWD
//